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Mahdi Garelnabi

Mahdi Garelnabi
Dr. Mahdi O. GarelnabiAssociate Professor

Research Interests

Atherosclerosis, Lipoprotein, Inflammation, antioxidants, oxidative stress, cardiovascular diseases, reproductive medicine, fertility, In vitro fertilization, laboratory medicine method validation

Atherosclerosis, Lipoprotein, Inflammation, antioxidants, oxidative stress, cardiovascular diseases, reproductive medicine, fertility, In vitro fertilization, laboratory medicine method validation

Education

  • Other: Basic of Mass Spectrometry Theory, (2011), AACC, USA - USA
  • Other: Clinical Laboratory Leadership & Management, (2010), AACC, USA - USA
  • Other: Point of Care Testing, (2009), AACC, USA - USA
  • Ph D: Clinical Biochemistry, (2001), Medical College & G.B. Pant Hospital, University of Delhi, India - Delhi, India
  • MS: Clinical Biochemistry, (1994), Grant Medical College & J.J. Group of Hospitals, University of Bombay - Bombay, India
  • Other: Nutrition & Dietetics DND, (1993), Institute of Health Care Administration - Madras , India
  • Other: Medical Laboratory Technology (MLT)., (1990), The Bombay School of Medical Laboratory Technology - Bombay (India)
  • BS: Biology, (1987), Faculty of Education -

Biography

Dr. Mahdi Garelnabi earned a bachelor's degree in Biology from the University of Khartoum in Sudan, a Master of Science in Clinical Biochemistry from Bombay University in India and a PhD in Clinical Biochemistry from the MA Medical College at Delhi University. Dr. Garelnabi is an active member of several American and International professional organizations; he also serves in different capacity in these organizations. He is reviewer and an editorial board member for several scientific journals. He is currently an Assistant Professor in the Department of Clinical Laboratory and Nutritional Sciences at the University of Massachusetts in Lowell where he teach lipids biochemistry and physiological chemistry. Dr. Garelnabi mentored many undergraduate and graduate students through his research which focuses on the impact of inflammatory and oxidative stress processes on atherosclerosis. He has unique expertise in lipoprotein pathophysiology and molecular

Awards and Honors

  • Fellow (2014) - American Heart Association
  • Junior Investigator Travel Award (2005) - NAVBO, USA.
  • Senior Research Fellowship Award (2000), Scholarship/Research - UGC, India
  • Junior Research Fellowship Award (1998), Scholarship/Research - UGC, India

Publications

  • Garelnabi, M.O., Ainsworth, G. (2016) "Dietary Oxidized Linoleic Acid Ameliorate Plasma ApoA5 levels in C57BL mice," Journal of Clinical Lipidology 10:3 pp. 705
  • Garelnabi, M.O., Ainsworth, G. (2016) "Lipoprotein Metabolism: Dietary Oxidized Linoleic Acid Ameliorate Plasma ApoA5 levels in C57BL mice.," Journal of Clinical Lipidology 10: pp. 705
  • Wu, T., Mazhar, Z., Alsayrafi, D., Ainsworth, G., Garelnabi, M.O. (2015) "117 - p-Cymene Modulate Oxidative Stress and Inflammation Genes in Murine Macrophage," Free radical biology & medicine 87: pp. S59-S60
  • Ainsworth, G., Mahini, H., Alaimo, H., Jamil, N., Garelnabi, M.O. (2015) "Effect of oxidized linoleic acid on plasma apoC 3 levels in C57BL mice," The FASEB Journal 29:1 Supplement pp. 568.31
  • Ainsworth, G., Mahini, H., Garelnabi, M.O. (2015) "Oxidized Linoleic Acid Modulates Plasma Lipids and Associated Apolipoproteins in C57bl Mice," Arteriosclerosis, Thrombosis, and Vascular Biology 35:Suppl 1 pp. A539-A539
  • Mahini, H., Ainsworth, G., Garelnabi, M.O. (2015) "Strenuous exercise and quercetin intake stimulates aortic NFkB signaling," The FASEB Journal 29:1 Supplement pp. 568.10
  • Stella, A., Hsieh, S., Garelnabi, M.O., Horta, J., Rogers, E.J. (2015) "Adsorption of Homocysteine to Various Polymorphs of Titanium (IV) Oxide," Adsorption Science & Technology
  • Garelnabi, M.O., Younis, A. (2015) "Paraoxonase-1 enzyme activity assay for clinical samples: validation and correlation studies," Medical science monitor : international medical journal of experimental and clinical research 21: pp. 902-908
  • Stella, A., Hsieh, S., Garelnabi, M.O., Horta, J.E., Rogers, E. (2014) "Determination of Aminothiol Adsorption Properties of Nano-Sized Titanium (IV) Oxide by HPLC-FLD," Clinical Chemistry 60:10 (Suppl) pp. B-433
  • Mahini, H., Ainsworth, G., Garelnabi, M.O. (2014) "Exercise and quercetin intake reduces body weight in c57bl6 mice," Atherosclerosis 235:2 pp. e109-e110
  • Garelnabi, M.O., Mahini, H., Ainsworth, G. (2014) "Flavonoids and exercise but not the combination enhances plasma catalase levels in C57BL mice," Atherosclerosis 235:2 pp. e248
  • Garelnabi, M.O., Younis, A. (2014) "Paraoxonase-1 Enzyme Activity Assay for Clinical Samples: Validation and Correlation Studies," Clinical Chemistry 60:10 (Suppl) pp. B-318
  • Mahini, H., Ainsworth, G., Garelnabi, M.O. (2014) "Rigorous Exercise and Quercetin Intake Modulate Adiponectin and Reduce Body Weight in Normal C57BL6 Mice," Arteriosclerosis, Thrombosis, & Vascular Biology pp. P615 (Suppl)
  • Younis, A., Hawkins, K., Mahini, H., Butler, W., Garelnabi, M.O. (2014) "Serum tumor necrosis factor-a, interleukin-6, monocyte chemotactic protein-1 and paraoxonase-1 profiles in women with endometriosis, pcos, or unexplained infertility," Journal of Assisted Reproduction and Genetics 31:11 pp. 1445-1451
  • Garelnabi, M.O., Younis, A. (2014) "Paraoxonase-1 Enzyme Activity Assay for Clinical Samples: Validation and Correlation Studies," Medical Science Monitor
  • Abdelmoneim, Y.S., Clower, C., Nelsen, D., Butler, W., Mahini, H., Garelnabi, M.O. (2014) "Associations of necrosis factor-a, interluekin-6, monocyte chemotactic protein-1 and Paraoxonase-1 with endometriosis, PCOS, or unexplained Infertility during ovarian simulation," Journal of Assisted Reproduction and Genetics
  • Stella, A., Hsieh, S., Garelnabi, M.O., Horta, J.E., Rogers, E.J. (2014) "Determination of Aminothiol Adsorption Properties of Titanium(IV) Oxide Nanoparticles Using High-Performance Liquid Chromatography Fluorescence Detection," Adsorption Science & Technology 32:7 pp. 591
  • Garelnabi, M.O., Mahini, H. (2014) "Modulation of microRNA 21, 125 b and 451 expression by quercetin intake and exercise in mice fed atherogenic diet," Biomedicine and Preventive Nutrition 4:3 pp. 359-363
  • Garelnabi, M.O., Mahini, H. (2014) "Beneficial effects of flavonoids on the pathogenesis of atherosclerosis," 8th World Congress on Polyphenols Applications
  • Garelnabi, M.O. (2014) "Effects of quercetin on microRNA signaling associated with atherosclerosis," 8th World Congress on Polyphenols Applications
  • Mahini, H., Ainsworth, G., Garelnabi, M.O. (2014) "Exercise and quercetin intake reduces body weight in C57BL mice," Atherosclerosis 235:2 pp. e109-e110
  • Garelnabi, M.O., Mahini, H., Ainsworth, G. (2014) "Flavonoids and Exercise but not the combination enhances plasma catalase levels in C57BL6 mice," Atherosclerosis 235:2 pp. e248
  • Garelnabi, M.O., Mahini, H., Wilson, T.A. (2014) "Quercetin intake with exercise modulates lipoprotein metabolism and reduces atherosclerosis plaque formation," Journal of the International Society of Sports Nutrition 11:1
  • Garelnabi, M.O., Mahini, H. (2013) "Quercetin Intake Differentially Affects the Plasma Lipid Levels and Lipoproteins Associated Gene Expression in Normal C57b1 Female Mice," Circulation 127: pp. AP426
  • Garelnabi, M.O., Mahini, H., Massie, M., Cook, C., Santanam, N. (2013) "Quercetin Intake with Exercise Modulate Adipose Response in Mice Fed Atherogenic Diet," Arteriosclerosis, Thrombosis, & Vascular Biology pp. P136 (Suppl)
  • Younis, A., Hawkins, K., Dizer, S., Hughes, A., Butler, W., Garelnabi, M.O. (2013) "Ovarian stimulation for IUI-IVF alter cytokine, chemokine, and antioxidant levels in women with endometriosis, PCOS, or unexplained infertility," Fertility and Sterility 100:3 pp. S425 (Suppl)
  • Uzoigwe, J., Prum, T., Bresnahan, E., Garelnabi, M.O. (2013) "The Emerging Role of Outdoor and Indoor Air Pollution in Cardiovascular Disease," North American Journal of Medical Sciences 5:8 pp. 445-453
  • Garelnabi, M.O., Mahini, H. (2013) "Effect of Myricetin treatment on lipoprotein metabolism in 13-HODE exposed HepG2 cells," A-547-0009-00535, 81st European Atherosclerosis Society Congress
  • Garelnabi, M.O., Mahini, H. (2013) "Exercise mediates selected microRNA expression and promosotes plaque regression," A-547-0013-00913, 81st European Atherosclerosis Society Congress
  • Garelnabi, M.O., Lor, K., Jin, J., Chai, F., Santanam, N. (2013) "The paradox of ApoA5 modulation of triglycerides: Evidence from clinical and basic research," Clinical Biochemistry 46:1-2 pp. 12-19
  • Garelnabi, M.O., Horta, J.E., Veledar, E. (2012) "Platelet Activation in Ischemic Heart Disease: Role of Modulators and New Therapies,"
  • Garelnabi, M.O., Kakumanu, S., Litvinov, D. (2012) "Role of Oxidized Lipids in Atherosclerosis,"
  • Younis, A., Clower, C., Nelsen, D., Butler, W., Carvalho, A., Hok, E., Garelnabi, M.O. (2012) "The relationship between pregnancy and oxidative stress markers on patients undergoing ovarian stimulations," Journal of assisted reproduction and genetics pp. 1-7
  • Garelnabi, M.O., Veledar, E., White-Welkley, J., Santanam, N., Abramson, J., Weintraub, W., Parthasarathy, S. (2012) "Vitamin E differentially affects short term exercise induced changes in oxidative stress, lipids, and inflammatory markers," Nutrition, Metabolism & Cardiovascular Diseases 22:10 pp. 907-913
  • Younis, A., Clower, C., Nelsen, D., Butler, W., Garelnabi, M.O. (2011) "The Relationship between Pregnancy and Oxidative Stress Markers on Patients Undergoing Ivf/iui," Fertility and sterility 96:3
  • Garelnabi, M.O., Veledar, E., White-Welkley, J., Santanam, N., Abramson, J., Weintraub, W., Parthasarathy, S. (2011) "Vitamin E differentially affects short term exercise induced changes in oxidative stress, lipids, and inflammatory markers," Nutrition, Metabolism and Cardiovascular Diseases
  • Garelnabi, M.O. (2010) "Emerging evidences from the contribution of the traditional and new risk factors to the atherosclerosis pathogenesis," Journal of Medical Sciences 10:6 pp. 153-161
  • Garelnabi, M.O., Litvinov, D., Parthasarathy, S. (2010) "Evaluation of a gas chromatography method for azelaic acid determination in selected biological samples," North American Journal of Medical Sciences 2:9
  • Garelnabi, M.O., Veledar, E., Abramson, J., White-Welkley, J., Santanam, N., Weintraub, W., Parthasarathy, S. (2010) "Physical inactivity and cardiovascular risk: Baseline observations from men and premenopausal women," Journal of clinical laboratory analysis 24:2 pp. 100-105
  • Garelnabi, M.O., Gupta, V., Mallika, V., Bhattacharjee, J. (2010) "Platelets oxidative stress in Indian patients with ischemic heart disease," Journal of clinical laboratory analysis 24:1 pp. 49-54
  • Parthasarathy, S., Raghavamenon, A., Garelnabi, M.O., Santanam, N. (2010) "Oxidized low-density lipoprotein.," Methods in molecular biology (Clifton, N.J.) 610: pp. 403-17
  • Jaichander, P., Selvarajan, K., Garelnabi, M.O., Parthasarathy, S. (2008) "Induction of paraoxonase 1 and apolipoprotein A1 gene expression by aspirin," Journal of lipid research 49: pp. 2142-2148
  • Garelnabi, M.O., Brown, W.V., Le , N.A. (2008) "Evaluation of a novel colorimetric assay for free oxygen radicals as marker of oxidative stress.," Clinical biochemistry 41:14-15 pp. 1250-4
  • Wei, C., Penumetcha, M., Santanam, N., Liu, Y., Garelnabi, M.O., Parthasarathy, S. (2005) "Exercise might favor reverse cholesterol transport and lipoprotein clearance: Potential mechanism for its anti-atherosclerotic effects,," Biochimica et Biophysica Acta 1723 pp. 124-127

Presentations

  • Dietary Antioxidants and Exercise: Do They Help to Prevent Arteriosclerosis Pathogenesis?, February 2012 - UMass Lowell
  • Role of oxidized dietary lipids in cardiovascular disease, February 2012
  • Role of Exercise and antioxidants in Cardiovascular Health - Biomedical Engineering and Biotechnology Seminar, November 2011
  • Recent Research in Cardiovascular Disease and Sudden Cardiac Arrest: Causes, Prevention, and Education., October 2011
  • Introduction to Biomedical research, September 2011
  • Atherosclerosis and Cardiovascular disease, novel markers and new fronts, April 2008 - Sudan
  • Dietary oxidized linoleic acid lowers triglycerides via APOA5/APOClll dependent mechanisms, November 2007 - Washington, DC
  • Women Exercise, and cardiovascular diseases - Klassan Research day, April 2007
  • Effect of Oxidation on the Platelet-Activating Properties of Low-Density Lipoprotein, July 2006
  • Formation of High Density Lipoproteins Containing Both Apolipoprotein A-I and A-II in the Rabbit, March 2006
  • Antioxidant Availability and Low Density Lipoprotein Oxidation in Chronic Exercisers, November 2005 - Vanderbilt University School of Medicine
  • Exercise and Oxidative Stress: Any Role for Vitamin E?, July 2005 - Emory University school of Medicine
  • Proteomics science and its application in Cardiovascular disease, June 2005 - North Michigan University
  • Exercise as an Oxidative stress, what are the benefits, April 2005 - Louisville University School of Medicine

Contracts, Fellowships, Grants and Sponsored Research

  • CoPI: Egg Nutrition Center (), Grant - Egg Nutrition Center
  • CoPI: NIH. R01 (), Grant - NIH
  • PI: AHA Scientist Development (), Grant - AHA
  • PI: Cranberry Health Research Center (), Grant - UMass Dartmouth
  • PI: NIH R15 AREA (), Grant - NIH
  • PI: UMass SHE (), Grant - UMASS, Lowell
  • Determining Metabolites of Oxidized Linoleic Aced and the Mechanisms Mediating th (2013), -
    Garelnabi, M.O. (Principal)
  • UML Echo360 Lecture Program (2011), -
    Garelnabi, M.O. (Principal)
  • PI: Advancing Research, Scholarship and Creative Work (2011), Grant - UMASS, Lowell
  • PI: University of Massachusetts Lowell Startup (2009), Grant - UMASS, Lowell
  • PI: ECHO360 lecture capture technology (2011), Grant - UMASS, Lowell