Biomaterials, Tissue Engineering, Personalized Medicine, Hydrogels, Additive Manufacturing, Microfabrication, Cardiovascular Diseases, Biomineralization, Point of Care Diagnostics
Biomaterials, Tissue Engineering, Personalized Medicine, Hydrogels, Additive Manufacturing, Microfabrication, Origami, Cardiovascular Diseases, Biomineralization, Point of Care Diagnostics
My multidisciplinary group uses engineering approaches to solve problems in life sciences and medicine. The goal of our research program is to control and modulate cellular behavior for directing repair and regeneration of tissues. To achieve this goal, we use diverse tools from chemistry, cell biology, materials science, microfabrication, and engineering.We develop functional biomaterials using unconventional approaches to generate tissue-mimetics for clinical applications including regeneration of bone and cardiovascular tissues as well as wound healing. My lab also has expertise on developing point-of-care (POC) diagnostic platforms for detection of pathogenic diseases (both viral and bacterial), health conditions, forensic applications, and testing for environmental reagents. To overcome the limitations with the conventional methods, we develop rapid, portable, and reliable platforms for POC diagnostics. For example, earlier this year, we have developed a rapid and simple test for detection of the Covid-19 virus from bodily fluids in only 5 min. Specific research interests of my lab include developing i) next generation functional biomaterials for regenerative engineering, ii) new tools for origami-inspired tissue engineering, and organ-on-paper models, iii) paper-based biomaterials and medical devices to detect gradients of oxygen, nutrient, and small molecules, iv) in vitro disease models for personalized medicine, and v) low-cost POC diagnostics to solve problems in global health. The ultimate goal of my research is to improve human health and quality of life.
Gulden Camci-Unal's research at the interface of biomaterials, bioengineering, and POC diagnostics has made important contributions in generation of engineered platforms for cardiovascular and bone tissue engineering, wound healing, and disease detection including bacterial and viral conditions. Her current research interests include design and implementation of engineered biomaterials for regeneration of tissues, unconventional materials and medical devices for personalized medicine, and low-cost point of care diagnostics.
Camci-Unal’s research and teaching achievements include various awards such as the University of Massachusetts Lowell Teaching Excellence Award, Iowa State University Teaching Excellence Award, Runner-Up for the Massachusetts Medical Device Development Center (M2D2) $200K Challenge (2019, 2020), Wakonse Fellowship, Chevron-Phillips Award, Procter&Gamble Fellowship, NSF ADVANCE Travel Award, and finalist for BioFlux Innovation Award.
Her research has resulted in 69+ published manuscripts, 74+ conference abstracts, and 10+ patent applications so far. Her work has been published in various high impact journals such as Trends in Biotechnology, Advanced Materials, Nature Asia Materials, JACS, Biomaterials, Lab on a Chip, Soft Matter, and Tissue Engineering. She is an Editorial Board member of Scientific Reports (Nature Publishing Group), PLoS One, Journal of Biomaterials and Tissue Engineering, Regenerative Medicine Research, International Journal of Cardiovascular Research, International Journal of Bioprinting, Journal of Materials Science and Chemical Engineering, and Bioceramics Development and Applications, Gels, Regenerative Engineering and Translational Medicine, Frontiers in Cell and Developmental Biology - Stem Cell Research, Micromachines, and Engineered Regeneration.