Biomaterials, Tissue Engineering, Personalized Medicine, Hydrogels, Additive Manufacturing, Microfabrication, Cardiovascular Diseases, Biomineralization, Point of Care Diagnostics
My multidisciplinary group uses engineering approaches to solve problems in life sciences and medicine. The goal of this research program is to control and modulate cellular behavior for directing repair and regeneration of tissues. To achieve this goal, we use diverse tools from chemistry, cell biology, materials science, microfabrication, and engineering. The research accomplishments from our lab include development of multicellular and compartmentalized tissue mimetics for clinical applications including endothelialization of cardiovascular tissues, regeneration of bone, and invasion of tumors.
My research lab is interested in developing i) next generation functional biomaterials for regenerative engineering, ii) new tools for origami-inspired tissue engineering, and organ-on-paper models, iii) paper-based biomaterials and medical devices to detect gradients of oxygen, nutrient, and small molecules, iv) in vitro disease models for personalized medicine, and v) low-cost point-of-care diagnostics to solve problems in global health. The ultimate goal of my research is to improve human health and quality of life.
Google Scholar page
- Camci-Unal, G., Laromaine, A., Hong, E., Derda, R., Whitesides, G.M., “Biomineralization guided by paper templates”, Scientific Reports, 6, 27693, 2016.
- Camci-Unal, G., Newsome, D., Eustace, B., Whitesides, G.M., “Fibroblasts enhance migration of human lung cancer cells in a paper-based co-culture system”, Advanced Healthcare Materials, 5(6): 641-647, 2016.
- Camci-Unal, G., Annabi, N., Liao, R., Dokmeci, M.R., Khademhosseini, A., "Hydrogels for Cardiac Tissue Engineering”, Nature Asia Materials, 6, e99, DOI:10.1038/am.2014.19, 2014.
- Camci-Unal, G., Cuttica, D., Annabi, N., Demarchi, D., Khademhosseini, A., “Synthesis and Characterization of Hybrid Hyaluronic Acid-Gelatin Hydrogels”, Biomacromolecules, 14(4): 1085-1092, 2013.
- Camci-Unal, G., Nichol, J.W., Bae, H., Tekin, H., Bischoff, J. Khademhosseini, A., “Hydrogel surfaces to promote attachment and spreading of endothelial progenitor cells”, Journal of Tissue Engineering and Regenerative Medicine, 7(5): 337-347, 2012.
- Kaji, H., Camci-Unal, G., Langer, R., Khademhosseini, A., “Engineering systems for the generation of patterned co-cultures for controlling cell-cell interactions”, Biochimica et Biophysica Acta-General Subjects, 1810(3): 239-250, 2011.
Postdoctoral Fellow, Department of Chemistry and Chemical Biology
Ph.D. in Chemistry at Iowa State University (USA)
M.Sc. and B.Sc. in Chemical Engineering at Middle East Technical University (Turkey)
Gulden Camci-Unal received her Ph.D. in Chemistry at Iowa State University (USA) and her M.Sc. and B.Sc. degrees both in Chemical Engineering at Middle East Technical University (Turkey). Camci-Unal’s research at the interface of biomaterials and bioengineering has made important contributions in generation of engineered platforms for cardiac, cardiovascular and bone tissue engineering. Her research interests include design, synthesis, and characterization of functional biomaterials for applications in tissue engineering and regenerative medicine, development of in vitro disease models for personalized medicine, and low-cost point of care diagnostics. The overarching goal of her research is to improve human health and quality of life.
Camci-Unal’s research and teaching achievements include various awards such as the Iowa State University Teaching Excellence Award, Wakonse Fellowship, NSF ADVANCE Travel Award, Chevron-Phillips Award, Procter & Gamble Fellowship, and finalist for BioFlux Innovation Award. Her research has resulted in 51+ published manuscripts, 36+ conference abstracts, and 4+ patent applications so far. Her work has been published in high impact journals such as Advanced Materials, Nature Asia Materials, JACS, Biomaterials, Lab on a Chip, Soft Matter, and Tissue Engineering. She is an Editorial Board member of Scientific Reports (Nature Publishing Group), Journal of Biomaterials and Tissue Engineering, Regenerative Medicine Research, International Journal of Cardiovascular Research, International Journal of Bioprinting, and Journal of Materials Science and Chemical Engineering.