Ibrahim Ibrahim

Ibrahim Mahmoud Sayed Ibrahim, Ph.D.

Research Assistant Professor

Zuckerberg College of Health Sciences
Biomedical & Nutritional Sciences
Saab Emerging Technologies & Innovation Center, Rooms 203 & 204


Stem Cell, 2D Organoids, Host Pathogen Interaction, Viral Hepatitis, HEV


Postdoctoral Research: University of California San Diego, La Jolla, California, 2018-2022
Ph.D.: University of University of Ghent, Ghent, Belgium, 2013-2017
M.S.: University of Assiut, Assiut, Egypt, 2011
B.S.: University of Assiut, Assiut, Egypt, 2007

Selected Publications

  • Sayed IM, Ibeawuchi SR, Lie D, Anandachar MA, Pranadinata R, Raffatellu M, Das S. The interaction of enteric bacterial effectors with the host engulfment pathway control innate immune response. Gut microbes, 2021 Jan-Dec;13(1):1991776. doi: 10.1080/19490976.2021.1991776
  • Sayed IM*, Suarez K*, Lim E*, Singh S*, Pereira M, Ibeawuchi SR, Katkar G, Dunkel Y, Mittal Y, Chattopadhyay R, Guma M, Boland BS, Dulai PS, Sandborn WJ, Ghosh P, and Das S. Host engulfment pathway controls inflammation in Inflammatory Bowel Disease. FEBS J. 2020 Sep;287(18):3967-3988. doi: 10.1111/febs.15236. (* equally contributed).
  • Sayed IM, Verhoye L, Cocquerel L, Abbravanel F, Foquet L, Montpellier C, Debing Y, Farhoudi A, Wychowski C, Dubuisson J, Leroux-Roels G, Neyts J, Izopet J, Michiels T, Meuleman P. Study of hepatitis E virus infection of genotype 1 and 3 in mice with humanized liver. Gut, 2017; 66(5): 920–929.
  • Sayed IM, Verhoye L, Montpellier C, Abravanel F, Izopet J, Cocquerel L, Meuleman P. Study of hepatitis E virus ORF2 antigen kinetics in human-liver chimeric mice and its impact on HEV diagnosis. J Infect Dis. 2019 Jul 31;220(5):811-819. doi: 10.1093/infdis/jiz171.
  • Montpellier C, Wychowski C, Sayed IM, Meunier JC, Saliou JM, Ankavay M, Bull A, Pillez A, Abravanel F, Helle F, Brochot E, Drobecq H, Farhat R, Aliouat-Denis CM, Haddad JG, Izopet J, Meuleman P, Goffard A, Dubuisson J, Cocquerel L.Hepatitis E Virus Lifecycle and Identification of 3 Forms of the ORF2 Capsid Protein. Gastroenterology.  2018 Jan;154(1):211-223.
  • Sayed IM, Foquet L, Verhoye L, Abbravanel F, Farhoudi A, Leroux-Roels G, Izopet J, Meuleman P., Transmission of Hepatitis E virus infection into human liver chimeric FRG mice using patient plasma. Antiviral Research 141 (2017) 150-154.
  • Sayed IM, Chakraborty A, Abd El-Hafeez AA, Sharma A, Sahan AZ, Huang WJM, Sahoo D, Ghosh P, Hazra TK, Das S. The DNA Glycosylase NEIL2 Suppresses Fusobacterium-Infection-Induced Inflammation and DNA Damage in Colonic Epithelial Cells. Cells. 2020 Aug 28;9(9): E1980. doi: 10.3390/cells9091980. PMID: 32872214.
  • Sayed IM$, Sahan AZ$, Venkova T, Chakraborty A, Mukhopadhyay D, Bimczok D, Beswick EJ,  Reyes VE, Pinchuk I, Sahoo D, Ghosh P, Hazra TK*, Das S*. Helicobacter pylori infection down-regulates the DNA glycosylase NEIL2, resulting in increased genome damage and inflammation in gastric epithelial cells. Journal of Biological Chemistry, 2020. Jun 9: jbc.RA119.009981. doi: 10.1074/jbc.RA119.009981. PMID: 32518160
Complete list of published work in My Bibliography.