Skip to Main Content

Kenneth Marx


UMass Lowell Image
Kenneth A MarxProfessor Emeritus

Research Interests

Biochemistry, Physical Biochemistry, Data Mining, & Cheminformatics

Informatics based structure and classification studies of DNA and protein sequences from different organisms in the public databases using various computational approaches; Data mining of large biological, biomedical and molecular datasets; biosensor development; simulation and experimental verification of novel chiral metamaterialsÍ properties in the visible to THz

Education

  • Other, (1976), Worcester Foundation for experimental biology - Worcester
  • Other, (1974), University of Edinburgh - Scotland
  • Ph D: Physical Chemistry, (1973), University of California at Berkeley - Berkeley
  • BS: Chemistry, (1968), California State University at San Diego - San Diego

Biography

Prof. Marx got his B.S. in Chemistry from San Diego State University in 1968 and then his Ph.D. in Physical Chemistry in 1973 from the University of California Berkeley with Prof. John Hearst, doing his thesis research on some of the early characterization of the Human Repetitive DNA Sequences. He was then awarded a Muscular Dystrophy Society of America Fellowship to spend 2 years at the University of Edinburgh in the Institute of Animal Genetics from 1974 to 1976. After spending a transitional year as a postdoctoral fellow at the Worcester Foundation for Experimental Biology in Worcester Mass, he was hired in 1977 as an Assistant Professor of Chemistry at Dartmouth College and served as well as an Adjunct Professor in the Dartmouth Medical School in Hanover, NH. Upon coming to the University of Massachusetts Lowell in 1985, he quickly rose to Full Professor in 1989. In 1992, he received university approval to establish the Center for Intelligent Biomaterials, where he has served as Director to the present. Prof. Marx has received significant federal grant funding from a variety of federal sources (NIH, DOE, DOA, ARO, DARPA) as well as numerous industrial sources (many different pharmaceutical and biotech companies). He has: published over 200 papers, proceedings articles and book chapters in his different areas of research interest; has edited a recent MRT journal volume on nanomanufacturing; serves on two journal Editorial Boards (MRT, J. Bionanotech.) as well as review panels (NSF, Science Foundation Ireland). In 2000, he Co-Founded AnVil Informatics, Inc. a university spin-off company that received VC funding. He served on the Scientific Advisory Board of Anvil as well as a number of other companies.

Selected Publications

  • Kononova, O., Snijder, J., Kholodov, Y., Marx, K.A., Wuite, G.J., Roos, W.H., Barsegov, V. (2016). Fluctuating Nonlinear Spring Model of Mechanical Deformation of Biological Particles. Plos Computational Biology, 12(1) e1004729.
  • Alekseenko, A., Kononova, O., Kholodov, Y., Marx, K.A., Barsegov, V. (2016). SOP-GPU: influence of solvent-induced hydrodynamic interactions on dynamic structural transitions in protein assemblies. Journal Of Computational Chemistry, 37(17) 1537 - 1551.
  • Kononova, O., Kholodov, Y., Theisen, K.E., Marx, K.A., Dima, R.I., Ataullakhanov, F.I., Grishchuk, E.L., Barsegov, V. (2015). 52 Tubulin Bond Energies and Microtubule Biomechanics Determined from Nanoindentation in Silico. Journal Of Biomolecular Structure & Dynamics, 33 Suppl 1 35 - 36.
  • Kononova, O., Snijder, J., Marx, K.A., Wuite, G.J., Roos, W.H., Barsegov, V. (2015). Fluctuating Nonlinear Spring Model of Mechanical Deformation of Biological Particles. arXiv.org, e-Print Arch., Phys., 1-25.
  • Kononova, O., Litvinov, R.I., Zhmurov, A., Alekseenko, A., Cheng, C.H., Agarwal, S., Marx, K.A., Weisel, J.W., Barsegov, V. (2015). Molecular Mechanisms, Thermodynamics, and Dissociation Kinetics of Knob-Hole Interactions in Fibrin. arXiv.org, e-Print Arch., Phys., 1-32.
  • Kononova, O., Snijder, J., Brasch, M., Cornelissen, J., Dima, R.I., Marx, K.A., Wuite, G.J., Roos, W.H., Barsegov, V. (2015). Structural Transitions and Energy Landscape for Cowpea Chlorotic Mottle Virus Capsid Mechanics from Nanomanipulation in Vitro and in Silico. arXiv.org, e-Print Arch., Phys., 1-34.
  • Russell, K., Cheng, C., Bizzaro, J.W., Ponts, N., Emes, R.D., Le Roch, K., Marx, K.A., Horrocks, P. (2014). Homopolymer tract organization in the human malarial parasite Plasmodium falciparum and related apicomplexan parasites. BMC Genomics, 15 848.
  • Kononova, O., Kholodov, Y., Theisen Kelly, E., Marx Kenneth, A., Dima Ruxandra, I., Ataullakhanov Fazly, I., Grishchuk Ekaterina, L., Barsegov, V. (2014). Tubulin Bond Energies and Microtubule Biomechanics Determined from Nanoindentation in Silico. J Am Chem Soc, 136(49) 17036-45.
  • Russell, K., Cheng, C.h., Bizzaro, J., Ponts, N., Emes, R.f., Le Roch, K., Marx, K., Horrocks, P. (2014). Homopolymer tract organization in the human malarial parasite Plasmodium falciparum and related Apicomplexan parasites. BMC Genomics, 15(1).
  • Toubar, R., Zhmurov, A., Barsegov, V., Marx, K.A. (2013). Comparative Simulation Studies of Native and single-site mutant human beta-defensin-1 peptides. Journal of Biomolecular and Structural Dynamics, 31(2) 174-194.
  • Cheng, C., Leferovitch, J., Zhang, X., Bedelbaeva, K., Gourevitch, D., Heber-Katz, E., Hatcher, C., Basson, C., Marx, K.A. (2013). Keratin Gene Expression Profiles after Digit Amputation in C57Bl/6 vs Regenerative MRL Mice Imply an Early Regenerative Keratinocyte Activated-Like State. Physiological Genomics, (409-421).
  • Kononova, O., Snijder, J., Brasch, M., Cornelissen, J., Dima, R., Marx, K., Wuite, G., Roos, W., Barsegov, V. (2013). Structural transitions and energy landscape for cowpea chlorotic mottle virus capsid mechanics from nanomanipulation in vitro and in silico. Biophysical Journal, 105(8) 1893-1903.
  • Kononova, O., Litvinov, R., Zhmurov, A., Alekseenko, A., Cheng, C., Agarwal, S., Marx, K., Weisel, J., Barsegov, V. (2013). Molecular mechanisms, thermodynamics, and dissociation kinetics of knob-hole interactions in fibrin. Journal of Biological Chemistry, 288(31) 22681-22692.
  • Dewilde, A., Wang, G., Zhang, J., Marx, K., Therrien, J., Braunhut, S. (2013). Quartz crystal microbalance measurements of mitochondrial depolarization predicting chemically induced toxicity of vascular cells and macrophages. Analytical Biochemistry, 439(1) 50-61.
  • Fang, L., Wei, M., Wongkasem, N., Jaradat, H., Mokhlis, A., Shen, J., Akyurtlu, A., Marx, K.A., Barry, C.M., Mead, J.L. (2013). Tin assisted transfer of electroplated metal nanostructures and its application in flexible chiral metamaterials. Microelectronic Engineering, 107 42-49.
  • Cheng, C., Leferovich, J., Zhang, X., Bedelbaeva, K., Gourevitch, D., Hatcher, C., Basson, C., Heber-Katz, E., Marx, K. (2013). Keratin gene expression profiles after digit amputation in C57BL/6 vs. regenerative MRL mice imply an early regenerative keratinocyte activated-like state. Physiological Genomics, 45(11) 409-421.
  • Toubar, R.A., Zhmurov, A., Barsegov, V., Marx, K.A. (2012). Comparative simulation studies of native and single-site mutant human beta-defensin-1 peptides. Journal of Biomolecular Structure & Dynamics.
  • Zhou, T., Marx, K.A., Dewilde, A.H., McIntosh, D., Braunhut, S.J. (2012). Dynamic cell adhesion and viscoelastic signatures distinguish normal from malignant human mammary cells using quartz crystal microbalance. Analytical Biochemistry, 421(1) 164-171.
  • Wang, G., Zhang, J., Dewilde, A.H., Pal, A.K., Bello, D., Therrien, J.M., Braunhut, S.J., Marx, K.A. (2012). Understanding and correcting for carbon nanotube interferences with a commercial LDH cytotoxicity assay. Toxicology, 299(2-3) 99-111.
  • Dewilde, A.H., Wang, G., , Marx, K.A., Therrien, J.M., Braunhut, S.J. (2012). Use of the Quartz Crystal Microbalance (QCM) to Measure Mitochondrial Depolarization in Real Time and Predict Chemically-Induced Apoptosis of Human Pulmonary Endothelial Cells and Macrophages. Analytical Biochemistry.
  • Zhou, J., Grinstein, G., Marx, K.A. (2011). A heuristic for gene selection and visual prediction of sample type. International Journal of Data Mining and Bioinformatics, 5(4) 428-448.
  • Wang, G., Dewilde, A.H., Zhang, J., Pal, A., Vashist, M., Bello, D., Marx, K.A., Braunhut, S.J., Therrien, J.M. (2011). A living cell quartz crystal microbalance biosensor for continuous monitoring of cytotoxic responses of macrophages to single-walled carbon nanotubes. Particle and Fibre Toxicology, 8.
  • Wongkasem, N., Kamtongdee, C., Akyurtlu, A., Marx, K.A. (2010). Artificial multiple helices: Polarization and em properties. Journal of Optics, 12(7).
  • Marx, K.A., Flickinger, M. (2010). Smart Biomaterials and Biosensors: Intelligent Properties of Biomolecules and Cells in Hybrid Devices,. Encyclopedia of Industrial Biotechnology,, 4448-4483.
  • Marx, K.A., Zhou, T., McIntosh, D., Braunhut, S.J. (2009). Electropolymerized tyrosine-based thin films: Selective cell binding via peptide recognition to novel electropolymerized biomimetic tyrosine RGDY films. Analytical Biochemistry, 384(1) 86-95.
  • Cheng, C., Marx, K.A., Sharko, J., Grinstein, G.G., Odelberg, S., Simon, H. (2009). Evidence for Proximal to Distal Appendage Amputation Site Effects from Global Gene Expression Correlations Found in Newt Microarrays. Journal of Biomolecular Structure & Dynamics, 26(6).
  • Marx, K.A., Oh, S., Angelopoulos, A.P. (2008). Gold surface adsorption properties of the enzymatically polymerized amphiphilic decyl ester of L-Tyrosine. Journal of Macromolecular Science, Part A: Pure and Applied Chemistry, 45(7) 503-510.
  • Sharko, J., Grinstein, G., Marx, K.A. (2008). Vectorized Radviz and Its Application to Multiple Cluster Datasets. IEEE Transactions on Visualization and Computer Graphics, 14(6).
  • Marx, K.A., Zhou, T., Montrone, A., McIntosh, D., Braunhut, S.J. (2007). A comparative study of the cytoskeleton binding drugs nocodazole and taxol with a mammalian cell quartz crystal microbalance biosensor: Different dynamic responses and energy dissipation effects. Analytical Biochemistry, 361(1) 77-92.
  • Wongkasem, N., Akyurtlu, A., Marx, K.A., Dong, Q., Li, J., Goodhue, W.D. (2007). Development of chiral negative refractive index metamaterials for the terahertz frequency regime. IEEE Transactions on Antennas and Propagation, 55(11 I) 3052-3062.
  • Marx, K.A. (2007). Enabling nanomanufacturing using microscopy techniques. Microscopy research and technique, 70(6) 493-6.
  • Wongkasem, N., Akyurtlu, A., Marx, K.A., Goodhue, W.D., Li, J., Dong, Q., Ada, E.T. (2007). Fabrication of a novel micron scale Y-structure-based chiral metamaterial: Simulation and experimental analysis of its chiral and negative index properties in the terahertz and microwave regimes. Microscopy research and technique, 70(6) 497-505.
  • Wongkasem, N., Akyurtlu, A., Marx, K.A. (2007). Identification Classification of Chiral and Bianisotropic Metamaterials by Group Theory,. IEEE AP-S Int’l Symp.And USNC/URSI Nat’l Radio Science Meeting, Ottowa, Canada,.
  • Wassaf, D., Marx, K.A., Dima, R.I. (2007). Identification of functional patterns in protein families using sequence correlation entropy. Journal of Biomolecular Structure & Dynamics, 24(6).
  • Marx, K.A. (2007). Introduction: Enabling nanomanufacturing using microscopy techniques. Microscopy research and technique, 70(6) 493-496.
  • Wongkasem, N., Akyurtlu, A., Marx, K.A. (2007). Strong Negative Refractive Index in Gammadion Structure: Analysis and Experiment,. IEEE AP-S Int’l Symp. And USNC/URSI Nat’l Radio Science Meeting, Ottowa, Canada,.
  • Marx, K.A. (2007). The quartz crystal microbalance and the electrochemical QCM: applications to studies of thin polymer films, electron transfer systems, biological macromolecules, biosensors, and cells. Springer Series on Chemical Sensors and Biosensors, 5 371-424.
  • Marx, K.A. (2007). Toward understanding the intelligent properties of biological macromolecules-implications for their design into biosensors. Optical Science and Engineering, 118 3-81.
  • Hennemuth, B., Marx, K.A. (2006). DNA deformability changes of single base pair mutants within CDE binding sites in S. Cerevisiae centromere DNA correlate with measured chromosomal loss rates and CDE binding site symmetries. BMC Molecular Biology, 7.
  • Marx, K.A., Zhou, Y., Kishawi, I.Q. (2006). Evidence for long poly(dA).poly(dT) tracts in D. discoideum DNA at high frequencies and their preferential avoidance of nucleosomal DNA core regions. Journal of Biomolecular Structure and Dynamics, 23(4) 429-446.
  • Wongkasem, N., Akyurtlu, A., Marx, K.A. (2006). Group theory based design of isotropic negative refractive index metamaterials. Progress in Electromagnetics Research, 63 295-310.
  • Wongkasem, N., Akyurtlu, A., Marx, K.A. (2005). Analysis and Measurements of Chiral Metamaterial Properties,. IEEE AP-S Int’l Symp. And USNC/URSI Nat’l Radio Science Meeting, Washington, DC,, XXX.
  • Braunhut, S.J., McIntosh, D., Vorotnikova, E., Zhou, T., Marx, K.A. (2005). Detection of apoptosis and drug resistance of human breast cancer cells to taxane treatments using quartz crystal microbalance biosensor technology. Assay and Drug Development Technologies, 3(1) 77-88.
  • Marx, K.A., Zhou, T., Long, D. (2005). Electropolymerized films formed from the amphiphilic decyl esters of D- and L-tyrosine compared to L-tyrosine using the electrochemical quartz crystal microbalance. Biomacromolecules, 6(3) 1698-1706.
  • Marx, K.A., Zhou, Y., Kishawi, I.Q. (2005). Evidence for long poly(dA).poly(dT) tracts in D. discoideum DNA at high frequencies and their preferential avoidance of nucleosomal DNA core regions. Journal of Biomolecular Structure & Dynamics, 23(4) 429-446.
  • Marx, K.A., Zhou, T., Montrone, A., McIntosh, D., Braunhut, S.J. (2005). Quartz crystal microbalance biosensor study of endothelial cells and their extracellular matrix following cell removal: Evidence for transient cellular stress and viscoelastic changes during detachment and the elastic behavior of the pure matrix. Analytical Biochemistry, 343(1) 23-34.
  • Marx, K.A., McCarthy, J.F., Hoffman, P.E., Gee, A.G., O’Neil, P., Ujwal, M.L., Hotchkiss, J., Umar, A., Kapetanovic, I., Khan, J. (2004). Applications of Machine Learning and High-Dimensional Visualization in Cancer Detection, Diagnosis and Management, in Annals of New York Academy of Sciences,. Annals of New York Academy of Sciences, 1020 239-262.
  • Long, D.D., Grosse, I., Marx, K.A. (2004). Coding and non-coding DNA thermal stability differences in eukaryotes studied by melting simulation, base shuffling and DNA nearest neighbor frequency analysis. Biophysical chemistry, 110(1-2) 25-38.
  • Marx, K.A., Zhou, T., McIntosh, D., Braunhut, S.J., Vorotnikova, E. (2004). Development of a Smart Bandage: Applying Electrical Potential to Selectively Release Wound Healing Growth Factors from Cell Free Extracellular Matrices, Proceedings MRS: "Architecture and Applications of Biomaterials and Biomolecular Materials" Vol. EXS-1,. Materials Research Society, Pittsburgh, PA.,, 403-405.
  • Marx, K.A., Zhou, T., McIntosh, D., Braunhut, S.J. (2004). Electropolymerization of Biomimetic Peptide-Tyrosineamide Polymer Films for Specific Cell Attachment, Proceedings MRS: Architecture and Applications of Biomaterials and Biomolecular Materials" Vol. EXS-1,. Materials Research Society, Pittsburgh, PA.,, 169-171.
  • Marx, K.A., Lee, J.S., Sung, C. (2004). Enzymatic copolymerization alters the structure of unpolymerized mixtures of the biomimetic monomers: The amphiphilic decyl ester of L-tyrosine and L-tyrosineamide - An AFM investigation of nano- to micrometer-scale structure differences. Biomacromolecules, 5(5) 1869-1876.
  • Marx, K.A., Zhou, T., Warren, M., Braunhut, S.J. (2004). Evidence for Cell-Cell Cooperativity in Initial Adhesion and Spreading: A Quartz Crystal Microbalance Study, Proceedings MRS: " Architecture and Applications of Biomaterials and Biomolecular Materials " Vol. EXS-1,. Materials Research Society, Pittsburgh, PA.,, 173-175.
  • Marx, K.A., Zhou, T., McIntosh, D., Braunhut, S.J. (2004). Extracellular Matrix Studied in situ with the Quartz Crystal Microbalance: Documenting Cellular Stress During Removal and the Elastic Behavior of the Matrix, Proceedings MRS: Architecture and Applications of Biomaterials and Biomolecular Materials" Vol. EXS-1,. Materials Research Society, Pittsburgh, PA.,, 111-113.
  • Lee, J.S., Marx, K.A., Sung, C. (2004). High-resolution AFM images of nano-scale structures formed on the surface of self-assembled copolymers of the amphiphilic decyl ester of L-tyrosine and tyrosineamide formed on gold deposited on Mica. Microscopy and Microanalysis, 10(SUPPL. 2) 560-561.
  • Zhou, Y., Bizzaro, J.W., Marx, K.A. (2004). Homopolymer tract length dependent enrichments in functional regions of 27 eukaryotes and their novel dependence on the organism DNA (G+C)% composition. BMC Genomics, 5.
  • Marx, K.A., Zhou, T., Schulze, H., Braunhut, S.J., Warren, M. (2003). Crystal Quartz Microbalance Study of Endothelial Cell Number Dependent Differences in Initial Adhesion and Steady-State Behavior: Evidence for Cell-Cell Cooperativity in Initial Adhesion and Spreading,. Biotechnology progress, 19 987-999.
  • Marx, K.A., O'Neil, P., Hoffman, P., Ujwal, M.L. (2003). Data Mining the NCI Cancer Cell Line Compound GI50 Values: Identifying Quinone Subtypes Effective Against Melanoma and Leukemia Cell Classes. Journal of chemical information and computer sciences, 43(5) 1652-1667.
  • Bizzaro, J.W., Marx, K.A. (2003). Poly: A quantitative analysis tool for simple sequence repeat (SRR) tracts in DNA. BMC Bioinformatics, 4.
  • Marx, K.A. (2003). Quartz crystal microbalance: A useful tool for studying thin polymer films and complex biomolecular systems at the solution - Surface interface. Biomacromolecules, 4(5) 1099-1120.
  • Marx, K.A., Zhou, T., Montrone, A., Braunhut, S.J. (2002). A Quartz Crystal Microbalance Cell Biosensor: Detecting Nocodazole Dependent Microtubule Disruption Dynamics in Living Cells," Proceedings MRS: Advanced Biomaterials-Characterization, Tissue Engineering and Complexity,. Materials Research Society, Pittsburgh, PA, 711 125-132.
  • Marx, K.A., Zhou, T. (2002). Comparative study of electropolymerization versus adsorption of tyrosine and the decyl ester of tyrosine on platinum electrodes. Journal of Electroanalytical Chemistry, 521(1-2) 53-60.
  • Marx, K.A., Zhou, T., Montrone, A., Schulze, H., Braunhut, S.J. (2001). A quartz crystal microbalance cell biosensor: Detection of microtubule alterations in living cells at nM nocodazole concentrations. Biosensors and Bioelectronics, 16(9-12) 773-782.
  • Long, D.D., Marx, K.A., Zhou, T. (2001). Amperometric hydrogen peroxide sensor electrodes coated with electropolymerized tyrosine derivative and phenolic films. Journal of Electroanalytical Chemistry, 501(1-2) 107-113.
  • Minehan, D.S., Marx, K.A., Tripathy, S.K. (2001). DNA binding to electropolymerized polypyrrole: The dependence on film characteristics. Journal of Macromolecular Science - Pure and Applied Chemistry, 38 A(12) 1245-1258.
  • Da'dara, A., Tsai, M.H., Tao, L.F., Marx, K.A., Shoemaker, C.B., Harn, D.A., Skelly, P.J. (2001). Schistosoma mansoni: Molecular characterization of a tegumental Ca-ATPase (SMA3). Experimental parasitology, 98(4) 215-222.
  • Braunhut, S.J., Marx, K.A., Zhou, T., Schulze, H. (2000). A Quartz Crystal Microbalance cell biosensor: Detection of microtubule alterations in living endothelial cells. Molecular biology of the cell, 11.
  • Marx, K.A., Bizzaro, J.W., Blake, R.D., Hsien Tsai, M., Feng Tao, L. (2000). Experimental DNA melting behavior of the three major Schistosoma species. Molecular and biochemical parasitology, 107(2) 303-307.
  • Tsai, M.H., Marx, K.A., Ismail, M.M., Tao, L.F. (2000). Randomly amplified polymorphic DNA (RAPD) polymerase chain reaction assay for identification of Schistosoma mansoni strains sensitive or tolerant to anti-schistosomal drugs. Journal of Parasitology, 86(1) 146-149.
  • Marx, K.A., Alva, K.S., Sarma, R. (2000). Self-assembled micron-scale fibre structures are formed by amphiphilic decyl ester derivatives of the D- and L-tyrosine amino acids prior to and following enzymatic ring polymerization. Materials Science and Engineering C, 11(2) 155-163.
  • Zhou, T., Marx, K.A., Warren, M., Schulze, H., Braunhut, S.J. (2000). The quartz crystal microbalance as a continuous monitoring tool for the study of endothelial cell surface attachment and growth. Biotechnology progress, 16(2) 268-277.
  • Zhou, T., Braunhut, S.J., Medeiros, D., Marx, K.A. (1999). Cellular adhesion and spreading of endothelial cells monitored in real time using the quartz crystal microbalance. Materials Research Society Symposium - Proceedings, 550 177-182.
  • Braunhut, S.J., Marx, K.A., Zhou, T., Warren, M.C., Schulze, H.M. (1999). Endothelial cell (EC) adhesion and spreading studied with the quartz crystal microbalance (QCM). Molecular biology of the cell, 10.
  • Marx, K.A., Zhou, T., Sarma, R. (1999). Quartz crystal microbalance measurement of self-assembled micellar tubules of the amphiphilic decyl ester of D-tyrosine and their enzymatic polymerization. Biotechnology progress, 15(3) 522-528.
  • Blake, R.D., Bizzaro, J.W., Blake, J.D., Day, G.R., Delcourt, S.G., Knowles, J., Marx, K.A., SantaLucia Jr., J. (1999). Statistical mechanical simulation of polymeric DNA melting with MELTSIM. Bioinformatics, 15(5) 370-375.
  • Li, A.Z., Marx, K.A. (1999). The iso-competition point for counterion competition binding to DNA: Calculated multivalent versus monovalent cation binding equivalence. Biophysical journal, 77(1) 114-122.
  • Li, A.Z., Huang, H., Re, X., Qi, L.J., Marx, K.A. (1998). A gel electrophoresis study of the competitive effects of monovalent counterion on the extent of divalent counterions binding to DNA. Biophysical journal, 74(2 I) 964-973.
  • Alva, K.S., Kumar, J., Marx, K.A., Tripathy, S.K. (1998). Biochemical synthesis of electroactive polymers. Proceedings of SPIE-The International Society for Optical Engineering, 3321 586-597.
  • Marx, K.A., Assil, I.Q., Bizzaro, J.W., Blake, R.D. (1998). Comparison of experimental to MELTSIM calculated DNA melting of the (A+T) rich Dictyostelium discoideum genome: Denaturation maps distinguish exons from introns. Journal of Biomolecular Structure and Dynamics, 16(2) 329-339.
  • Bizzaro, J.W., Marx, K.A., Blake, R.D. (1998). Comparison of experimental with theoretical melting of the yeast genome and individual yeast chromosome denaturation mapping using the program MELTSIM. Materials Research Society Symposium Proceedings, 489 73-77.
  • Pande, R., Ruben, G.C., Lim, J.O., Tripathy, S., Marx, K.A. (1998). DNA bound to polypyrrole films: High-resolution imaging, DNA binding kinetics and internal migration. Biomaterials, 19(18) 1657-1667.
  • Sarma, R., Alva, K.S., Marx, K.A., Akkara, J.A., Kaplan, D.L., Tripathy, S.K. (1998). Horseradish peroxidase catalyzed polymerization of amphiphilic tyrosine derivatives in micelles. Proceedings of SPIE-The International Society for Optical Engineering, 3321 598-608.
  • Zhou, T., Braunhut, S.J., Medeiros, D., Marx, K.A. (1998). Potential dependent endothelial cell adhesion, growth and cytoskeletal rearrangements. Materials Research Society Symposium Proceedings, 489 211-216.
  • Marx, K.A., Bizzaro, J.W., Assil, I., Blake, R.D. (1997). Comparison of experimental and theoretical melting behavior of DNA. Materials Research Society Symposium Proceedings, 463 147-152.
  • Alva, K.S., Kumar, J., Marx, K.A., Tripathy, S.K. (1997). Enzymatic synthesis and characterization of a novel water-soluble polyaniline: Poly(2,5-diaminobenzenesulfonate). Macromolecules, 30(14) 4024-4029.
  • Qi, L.J., Leung, A.T., Xiong, Y., Marx, K.A., Abou-Samra, A.B. (1997). Extracellular cysteines of the corticotropin-releasing factor receptor are critical for ligand interaction. Biochemistry, 36(41) 12442-12448.
  • Li, A.Z., Huang, H.Y., Marx, K.A. (1997). Iso-competition point and divalent counterion binding. Biophysical journal, 72(2).
  • Alva, K.S., Marx, K.A., Kumar, J., Tripathy, S.K. (1997). Mechanistic study of enzyme catalyzed polymerization of 8-hydroxyquinoline-5-sulfonate using nuclear magnetic resonance spectroscopy. Macromolecular Rapid Communications, 18(2) 133-137.
  • Shridhara, K., Marx, K.A., Kumar, J., Tripathy, S.T. (1997). Mechanistic study of enzyme-catalyzed polymerization of 8-hydroxyquinoline-5-sulfonate using nuclear magnetic resonance spectroscopy. Macromolecular Rapid Communications, 18(2) 133-137.
  • Li, A.Z., Marx, K.A., Walker, J., Kaplan, D.L. (1997). Trinitrotoluene and metabolites binding to humic acid. Environmental Science and Technology, 31(2) 584-589.
  • Chen, Z., Kaplan, D.L., Yang, K., Kumar, J., Marx, K.A., Tripathy, S.K. (1997). Two-photon-induced fluorescence from the phycoerythrin protein. Applied Optics, 36(7) 1655-1659.
  • Pande, R., Kamtekar, S., Ayyagari, M.S., Kamath, M., Marx, K.A., Kumar, J., Tripathy, S.K., Kaplan, D.L. (1996). A biotinylated undecylthiophene copolymer bioconjugate for surface immobilization: Creating an alkaline phosphatase chemiluminescence-based biosensor. Bioconjugate chemistry, 7(1) 159-164.
  • Chen, Z., Chittibabu, K.G., Li, L., Marx, K.A., Kumar, J., Tripathy, S.K., Kaplan, D.L. (1996). Bacteriorhodopsin Encapsulated in Conducting Polymer: A Biomaterial for Signal Transduction,. Advanced Materials,.
  • Alva, K.S., Marx, K.A., Kumar, J., Tripathy, S.K. (1996). Biochemical synthesis of water soluble polyanilines: Poly(p-aminobenzoic acid). Macromolecular Rapid Communications, 17(12) 859-863.
  • Sarma, R., Alva, K.S., Marx, K.A., Tripathy, S.K., Akkara, J.A., Kaplan, D.L. (1996). Enzymatic polymerization of amphiphilic alkyl tyrosine derivatives from emulsions. Materials Science and Engineering C, 4(3) 189-192.
  • Shridhara Alva, K., Kumar, J., Marx, K.A., Kaplan, D.L., Tripathy, S.K. (1996). Enzymatic Synthesis of Poly(diaminoazobenzene): Spectral Characterization,. Makromolecular Chemistry Rapid Commun.
  • Chen, Z., Kaplan, D.L., Gao, H., Kumar, J., Marx, K.A., Tripathy, S.K. (1996). Molecular assembly of multilayer enzyme: Toward the development of a chemiluminescence-based fiber optic biosensor. Materials Science and Engineering C, 4(3) 155-159.
  • Chen, Z., Kaplan, D.L., Yang, K., Kumar, J., Marx, K.A., Tripathy, S.K. (1996). Phycobiliproteins encapsulated in sol-gel glass. Journal of Sol-Gel Science and Technology, 7(1-2) 99-108.
  • Samuelson, L.A., Pande, R., Ayyagari, M.S., Kamtekar, S., Chittibabu, K.G., Gao, H., Marx, K.A., Kumar, J., Tripathy, S.K., Kaplan, D.L., Salamone, J.C. (1996). Signal Transduction Composites: Biomaterials with Electroactive Polymers, Polymeric Materials Encyclopedia: Synthesis, Properties and Applications,. Polymer Science and Technology Series,, 10(QS) 7612-7620.
  • Kamtekar, S.D., Pande, R., Ayyagari, M.S., Marx, K.A., Kaplan, D.L., Kumar, J., Tripathy, S. (1996). Trace analysis of Zn(II), Be(II), and Bi(III) by enzyme-catalyzed chemiluminescence. Analytical Chemistry, 68(1) 216-220.
  • Li, A.Z., Lai Jun Qi, ., Shih, H.H., Marx, K.A. (1996). Trivalent counterion condensation on DNA measured by pulse gel electrophoresis. Biopolymers, 38(3) 367-376.
  • Kamtekar, S.D., Pande, R., Ayyagari, M.S., Marx, K.A., Kaplan, D.L., Kumar, J., Tripathy, S.K. (1995). A chemiluminescence-based biosensor for metal ion detection. Materials Science and Engineering C, 3(2) 79-83.
  • Ayyagari, M.S., Kamtekar, S., Pande, R., Marx, K.A., Kumar, J., Tripathy, S.K., Kaplan, D.L. (1995). Biosensors for pesticide detection based on alkaline phosphatase-catalyzed chemiluminescence. Materials Science and Engineering C, 2(4) 191-196.
  • Ayyagari, M.S., Kamtekar, S., Pande, R., Marx, K.A., Kumar, J., Tripathy, S.K., Akkara, J., Kaplan, D.L. (1995). Chemiluminescence-based inhibition kinetics of alkaline phosphatase in the development of a pesticide biosensor. Biotechnology progress, 11(6) 699-703.
  • Ayyagari, M.S., Marx, K.A., Tripathy, S.K., Akkara, J.A., Kaplan, D.L. (1995). Controlled free-radical polymerization of phenol derivatives by enzyme-catalyzed reactions in organic solvents. Macromolecules, 28(15) 5192-5197.
  • Bruno, F.F., Akkara, J.A., Kaplan, D.L., Sekher, P., Marx, K.A., Tripathy, S.K. (1995). Enzyme-mediated two-dimensional polymerization of aromatic derivatives on a Langmuir trough. Industrial and Engineering Chemistry Research, 34(11) 4009-4015.
  • Ayyagari, M.S., Pande, R., Kamtekar, S., Gao, H., Marx, K.A., Kumar, J., Tripathy, S.K., Akkara, J.A., Kaplan, D.L. (1995). Molecular assembly of proteins and conjugated polymers: Toward development of biosensors. Biotechnology and bioengineering, 45(2) 116-121.
  • Chen, Z., Samuelson, L.A., Akkara, J., Kaplan, D.L., Gao, H., Kumar, J., Marx, K.A., Tripathy, S.K. (1995). Sol-gel encapsulated light-transducing protein phycoerythrin: A new biomaterial. Chemistry of Materials, 7(10) 1779-1783.
  • Bruno, F.F., Akkara, J.A., Samuelson, L.A., Kaplan, D.L., Mandal, B.K., Marx, K.A., Tripathy, S.K. (1995). Synthesis and characterization of polyphenols and polyanilines from peroxidase-mediated reactions on a Langmuir trough. Advances in Science and Technology (Faenza, Italy), 10 99-106.
  • Akkara, J.A., Bruno, F., Samuelson, L.A., Salapu, P., Kaplan, D.L., Mandal, B.K., Marx, K.A., Tripathy, S. (1995). Synthesis and Characterization of Polyphenols From Peroxidase Catalyzed Reactions,. J.Enzymatic and Microbial Technology.
  • Tao, L.F., Marx, K.A., Wongwit, W., Jiang, Z.W., Agrawal, S., Coleman, R.M. (1995). Uptake, Intracellular-Distribution, and Stability of Oligodeoxynucleotide Phosphorothioate by Schistosoma-Mansoni. Antisense Research and Development, 5(2).
  • Marx, K.A., Hess, S.T., Blake, R.D. (1994). Alignment of (dA).(dT) homopolymer tracts in gene flanking sequences suggests nucleosomal periodicity in D. discoideum DNA. Journal of Biomolecular Structure and Dynamics, 12(1) 235-246.
  • Akkara, J.A., Ayyagari, M., Bruno, F.F., Samuelson, L., John, V.T., Karayigitoglu, C., Tripathy, S., Marx, K.A., Roa, D.V., Kaplan, D.L. (1994). Biomimetic Membrane and Interface Templates for Enzyme-Based Polymerization Reactions,. Biomimetics,, 2 331-339.
  • Ayyagari, M., Pande, R., Lim, J.O., Kamath, M., Beladakere, N., Gao, H., Marx, K.A., Tripathy, S., Kumar, J., et, a. (1994). Biotinylated polyalkylthiophene thin films and monolayers that specifically incorporate phycobiliproteins: Toward smart materials. Proceedings of SPIE-The International Society for Optical Engineering, 2189 116-25.
  • Tripathy, S.K., Chen, Z.P., Chittibabu, K.G., Marx, K.A., Kumar, J., Samuelson, L.A., Akkara, J., Kaplan, D.L. (1994). Conducting Polymer and Sol-Gel Encapsulated Photodynamic Protein as Biomaterials for Signal-Transduction. Abstracts of Papers of the American Chemical Society, 208.
  • Bruno, F.F., Marx, K.A., Tripathy, S.K., Akkara, J.A., Samuelson, L.A., Kaplan, D.L. (1994). Enzyme catalyzed polymerization of phenol and aniline derivatives on a Langmuir trough to form ordered 2-D polymer films. Journal of Intelligent Material Systems and Structures, 5(5) 631-634.
  • Marx, K.A., Lim, J.O., Minehan, D., Pande, R., Kamath, M., Tripathy, S.K. (1994). Intelligent materials properties of DNA and strategies for its incorporation into electroactive polymeric thin film systems. Journal of Intelligent Material Systems and Structures, 5(4) 447-454.
  • Samuelson, L.A., Wiley, B., Kaplan, D.L., Sengupta, S., Kamath, M., Lim, J.O., Cazeca, M., Kumar, J., Marx, K.A., Tripathy, S.K. (1994). Intelligent Systems Based on Ordered Arrays of Biological Molecules using the Lb Technique. Journal of Intelligent Material Systems and Structures, 5(3).
  • Minehan, D.S., Marx, K.A., Tripathy, S.K. (1994). Kinetics of Dna-Binding to Electrically Conducting Polypyrrole Films. Macromolecules, 27(3).
  • Samuelson, L.A., Kaplan, D.L., Lim, J.O., Kamath, M., Marx, K.A., Tripathy, S.K. (1994). Molecular recognition between a biotinylated polythiophene copolymer and phycoerythrin utilizing the biotin-streptavidin interaction. Thin Solid Films, 242(1-2) 50-55.
  • Ayyagari, M.S., Gao, H.H., Bihari, B., Chittibabu, K.G., Kumar, J., Marx, K.A., Kaplan, D.L., Tripathy, S.K. (1994). Molecular self assembly on optical fiber-based fluorescence sensor. Proceedings of SPIE - The International Society for Optical Engineering, 2068 168-178.
  • Chen, Z., Chittibabu, K.G., Marx, K.A., Kumar, J., Tripathy, S.K., Samuelson, L.A., Akkara, J., Kaplan, D.L. (1994). Photodynamic protein incorporated in conducting polymer and sol-gel matrixes: Toward smart materials for information storage and processing. Proceedings of SPIE-The International Society for Optical Engineering, 2189 105-15.
  • Chen, Z., Lewis, A., Kumar, J., Tripathy, S., Marx, K.A., Akkara, J., Kaplan, D., Navia, M. (1994). Second Harmonic Generation of Bacteriorhodopsin and Its Application for Three-Dimensional Optical Memory,. Proc. MRS.,, 330 263-268.
  • Kamath, M., Lim, J.O., Chittibabu, K.G., Sarma, R., Kumar, J., Marx, K.A., Tripathy, S.K., Samuelson, L.A., Akkara, J.A., Kaplan, D.L. (1993). Biotinylated poly(3-hexylthiophene-co-3-methanolthiophene): A Langmuir monolayer-forming copolymer. Journal of Macromolecular Science - Pure and Applied Chemistry, A30(8) 493-502.
  • Marx, K.A., Hess, S.T., Blake, R.D. (1993). Characteristics of the large (dA).(dT) homopolymer tracts in D. discoideum gene flanking and intron sequences. Journal of Biomolecular Structure and Dynamics, 11(1) 57-66.
  • Akkara, J.A., Bruno, F., Samuelson, L., Ayyagari, M., Tripathy, S., Marx, K.A., John, V.T., Kaplan, D.L. (1993). Synthesis of 2-Dimensional Electrooptic Polymer Networks through Biocatalysis. Abstracts of Papers of the American Chemical Society, 206.
  • Samuelson, L.A., Lim, J.O., Kamath, M., Marx, K.A., Tripathy, S.K., Kaplan, D.L. (1993). The Coupling of a Thiophene Copolymer to a Photoactive Antennae Protein using Biotin Streptavidin Complexation. Abstracts of Papers of the American Chemical Society, 206.
  • Bruno, F.F., Akkara, J.A., Samuelson, L.A., Kaplan, D.L., Marx, K.A., Tripathy, S.K. (1993). The enzymic mediated polymerization of phenol and aniline derivatives on a Langmuir trough. Materials Research Society Symposium Proceedings, 292 147-52.
  • Samuelson, L.A., Marx, K.A., Kumar, J., Tripathy, S.K., Wiley, B., Sengupta, S., Cazeca, M., Kaplan, D.L., Takagi, T., Takahashi, K., Aizawa, M., Miyata, S. (1992). Demonstration of an LB Monolayer Cassette Strategy for Forming Ordered Arrays of Biological Molecules: The Biotinylated B-DPPE-Lipid Monolayer-Streptavidin-Biotinylated Phycoerythrin Film, in Proceedings of First International Conference on Intelligent Materials,. Technomic Publishing Co., Lancaster, PA.,, 65-73.
  • Lim, J.O., Minehan, D.S., Kamath, M., Marx, K.A., Tripathy, S.K. (1992). DNA binding to conducting polymer films. Materials Research Society Symposium Proceedings, 255 195-200.
  • Takagi, T., Takahashi, K., Aizawa, M., Miyata, S., Bruno, F., Akkara, J.A., Samuelson, L.A., Mandal, B.K., Kaplan, D.L., Marx, K.A., Tripathy, S. (1992). Enzyme Catalyzed 2-D Polymerization of Phenol and Aniline Derivatives on a Langmuir-Blodgett Trough, in Proceedings of First International Conference on Intelligent Materials,. Technomic Publishing Co., Lancaster, PA.,, 78-83.
  • Marx, K.A., Denial, T. (1992). High affinity DNA-microtubule interactions: Evidence for a conserved DNA- MAP interaction involving unusual high CsCl density repetitious DNA families. Molecular and cellular biochemistry, 118(1) 39-48.
  • Marx, K.A., Denial, T. (1992). High-Affinity Dna-Microtubule Interactions - Evidence for a Conserved Dna-Map Interaction Involving Unusual High Cscl Density Repetitious Dna Families. Molecular and cellular biochemistry, 118(1).
  • Samuelson, L., Miller, P., Galotti, D., Marx, K.A., Kumar, J., Tripathy, S., Kaplan, D. (1992). Langmuir-Blodgett films of streptavidin-conjugated phycoerythrin bound to biotinylated monolayers. Thin Solid Films, 210-211(PART 2) 796-798.
  • Samuelson, L.A., Yang, Y., Marx, K.A., Kumar, J., Tripathy, S.K., Kaplan, D.L. (1992). Surface Specific Monolayer Attachment of a Photodynamic Protein Through Biotin-Streptavidin Complexation: Demonstration of a Cassette Approach. Biomimetics, 1(1) 51-61.
  • Mello, C.M., Marx, K.A. (1992). The Affinity of Dna-Microtubule Protein Complexes and their Disruption by Tubulin Binding-Drugs. Journal of Biomolecular Structure & Dynamics, 9(4).
  • Samuelson, L.A., Miller, P., Galotti, D.M., Marx, K.A., Kumar, J., Tripathy, S.K., Kaplan, D.L. (1992). The monomolecular organization of a photodynamic protein system through specific surface recognition of streptavidin by biotinylated Langmuir-Blodgett films. Langmuir, 8(2) 604-608.
  • Marx, K.A., Dwyer, K.J. (1991). Comparative Dna Southwestern Blots of Microtubule Proteins and Fitc Labeled Microtubule Proteins Electrophoretically Fractionated in Different Gel Systems. FASEB Journal, 5(4).
  • Mello, C.M., Dwyer, K.D., Marx, K.A. (1991). Gel Mobility Shift Assay on Microtubule Proteins with Centromere Associated Dna. FASEB Journal, 5(4).
  • Samuelson, L.A., Miller, P., Galotti, D.M., Marx, K.A., Kumar, J., Tripathy, S., Kaplan, D.L., Renugopalakrishnan, V., Carey, P.R., Smith, I.C., Huang, S.G., Storer, A.C. (1991). Oriented Fluorescent Streptavidin Conjugated Phycoerythrin Protein on Biotinylated Lipid L-B Monolayer Films, in Proteins Structure, Dynamics and Design. Escom Science Publishers BV, Leiden, Netherlands,, 160-164.
  • Dwyer, K.J., Mello, C.M., Marx, K.A. (1991). Southwestern Blot Binding of Total Genomic Calf Thymus Dna by Calf Brain Microtubule Proteins and Heat-Stable Calf Brain Proteins. FASEB Journal, 5(4).
  • Samuelson, L.A., Kaplan, D.L., Marx, K.A., Miller, P., Galotti, D.M., Kumar, J., Tripathy, S., Alper, M., Rieke, P.C., Frankel, R., Calvert, P.D., Tirrell, D.A. (1991). Streptavidin-Phycoerythrin Conjugated Proteins Bound to Biotin on Langmuir-Blodgett Films of Biotinylated Lipid Monolayers, in Materials Synthesis Based on Biological Processes,. MRS, 218 159-164.
  • Samuelson, L.A., Miller, P., Galotti, D.M., Marx, K.A., Kumar, J., Tripathy, S.K., Kaplan, D.L. (1991). Surface Specific Recognition of Fluorescent Conjugated Streptavidin-Phycoerythrin Proteins Onto Biotin Lipid Lb Monolayer Films. Abstracts of Papers of the American Chemical Society, 201.
  • Mello, C.M., Marx, K.A. (1991). The affinity of DNA-microtubule protein complexes and their disruption by tubulin binding drugs. Journal of Biomolecular Structure and Dynamics, 9(4) 791-805.
  • Dwyer, K.J., Marx, K.A. (1990). Comparative Dna Western Blots of Microtubule Proteins Electrophoretically Fractionated in Different Gel Systems. Abstracts of Papers of the American Chemical Society, 199.
  • Freeman, J.A., Marx, K.A. (1990). Isolation and Characterization of the 1.688 G/ml Satellite Dna of Dictyostelium-Discoideum. Biochemistry, 29(8).
  • Mello, C.M., Jahngen, E.G., Marx, K.A., Thayer, J. (1990). Purification of Plasmid Dna from Escherichia-Coli Alkaline Lysates by Hplc. Abstracts of Papers of the American Chemical Society, 199.
  • Aksiyotebenbasat, J., Ruben, G.C., Marx, K.A. (1990). Solution Structure of Bacteriophage-T4d and Icosahedral Capsid Geometry Visualized in Freeze-Fractured, Deep-Etched Replicas. Journal of Biomolecular Structure & Dynamics, 7(4).
  • Freeman, J.A., Marx, K.A. (1990). The Isolation and Characterization of the 1.688g/ml Satellite Dna of Dictyostelium-Discoideum. Abstracts of Papers of the American Chemical Society, 199.
  • Marx, K.A., Kruger, R., Clarke, M.J. (1989). Binding of the transition metal ion [(H2O)(NH3)5Ru(II)]2+ to nucleosomal core and internucleosomal DNA. Molecular and cellular biochemistry, 86(2) 155-162.
  • Marx, K.A., Reynolds, T.C. (1989). Micrococcal nuclease digestion study of spermidine-condensed DNA. International journal of biological macromolecules, 11(4) 241-248.
  • Marx, K.A., Seery, C., Malloy, P. (1989). Reduced RNA Synthesis Levels in Isolated Nuclei Following Reaction with Aquopentaamineruthenium(II),. Molecular and cellular biochemistry, 90 37-45.
  • Ruben, G.C., Marx, K.A., Benbasat, J., Bailey, G.W. (1988). Direct Stereoscopic Visualization of Icosahedral Capsid Geometry in Bacteriophage T4 Freeze-Fractured, Deep-Etched Replicas, in Proceedings of the 46th Annual Meeting of the Electron Microscopy Society of America,. San Francisco Press, Inc., San Francisco,, 316-317.
  • Marx, K.A., Nicolini, C. (1987). Toroidal DNA Condensates; Aspects of Formation, Structure, Dynamics and Biological Implications," Structure and Dynamics of Biopolymers, NATO ASI Series E 133,. Martinus Nijhoff Pub.,, 137-168.
  • Marx, K.A., Ruben, G.C. (1986). A study of X-174 DNA torus and lambda DNA torus tertiary structure and the implications for DNA self-assembly. Journal of Biomolecular Structure and Dynamics, 4(1) 23-39.
  • Clarke, M.J., Jansen, B., Marx, K.A., Kruger, R. (1986). Biochemical Effects of Binding Aquopentaamineruthenium(II) to DNA and Oxidation to Aquopentaamineruthenium(III)n-DNA,. Inorganica Chimica Acta, 124 13-28.
  • Marx, K.A., Ruben, G.C. (1986). Hydrated Macromolecular Assembly Structure Revealed by Freeze-Etch Stereo-Electron Microscopy,. Biophysical journal, 49 53-55.
  • Marx, K.A., Denial, T. (1985). Chromosome Segregation, Kinetochores and DNA-Microtubule Interaction: A Preferential Satellite DNA-MAP Interaction May Be Conserved in Evolution," in The Molecular Basis of Cancer Progress in Clinical and Biological Research 172B,. Alan R. Liss, Inc., New York,, 65-75.
  • Marx, K.A., Ruben, G.C. (1985). DNA Tertiary Structure of Disk Shaped Toruses: An in Vitro Viral DNA Model System," in The Molecular Basis of Cancer Progress in Clinical and Biological Research 172A. Alan R. Liss, Inc., New York,, 131-140.
  • Ruben, G.C., Marx, K.A. (1985). Torus Circumference and Thickness Parameters From a Linear DNA Size Series Suggest How Toruses Self-Assemble," Proceedings of the 43rd Annual Meeting of the Electron Microscopy Society of America San Francisco Press,. Inc., San Francisco,, 522-523.
  • Ruben, G.C., Marx, K.A., Bailey, G.W. (1984). Discrimination of Monomer From Multimer DNA Disk Shaped Toruses by Freeze-Etch TEM," Proceedings of the 42nd Annual Meeting of the Electron Microscopy Society of America,. San Francisco Press, Inc., San Francisco,, 210-211.
  • Ruben, G.C., Marx, K.A., Bailey, G.W. (1984). Freeze-Etch Toruses of Circular and Linear DNA Topological States Exhibit Characteristic Circumferencing Measurements," Proceedings of the 42nd Annual Meeting of the Electron Microscopy Society of America,. San Francisco Press, Inc., San Francisco,, 212-213.
  • Marx, K.A., Denial, T., Keller, T. (1984). High Affinity Microtubule Protein-Higher Organism DNA Complexes: Many Fold Enrichment in Repetitive Mouse DNA Sequences Comprised of Satellite DNAs,. Biochim. Biophysica Acta., 783 283-292.
  • Ruben, G.C., Marx, K.A. (1984). Parallax Measurements on Stereomicrographs of Hydrated Single Molecules, Their Accuracy and Precision at High Magnification,. Electron Microscopy Technique, 1 373-385.
  • Ruben, G.C., Marx, K.A., Bailey, G.W. (1984). Real Fibre Diameters From Freeze-Etched Pt-C Replicated Fibre Images: A DNA Study, Proceedings of the 42nd Annual Meeting of the Electron Microscopy Society of America,. San Francisco Press, Inc., San Francisco,, 684-685.
  • Ruben, G.C., Marx, K.A. (1984). Studies of DNA Organization in Hydrated Spermidine-condensed DNA Toruses and Spermidine-DNA Fibres. Biomolecular Structure and Dynamics, 1 1109-1132.
  • Ruben, G.C., Marx, K.A., Bailey, G.W. (1983). Deep-Etched, Replicated DNA Toruses Held on Edge in Ice Demonstrate a Complex 3-D Substructure by Extensive Tilting Along Shadowing Direction, Proceedings of the 41st Annual Meeting of the Electron Microscopy Society of America,. San Francisco Press, Inc., San Francisco,, 714-715.
  • Ruben, G.C., Marx, K.A. (1983). Evidence for Hydrated Spermidine-Calf Thymus DNA Toruses Organized by Circumferential DNA Wrapping,. Nucleic acids research, 11 1839-1853.
  • Marx, K.A., Reynolds, T.C. (1983). Ion Competition and Micrococcal Nuclease Digestion Studies of Spermidine-Condensed DNA: Evidence for Torus Organization by Circumferential DNA Wrapping,. Biochim. Biophysica Acta., 741 279-287.
  • Ruben, G.C., Marx, K.A., Bailey, G.W. (1983). Strategies for Error Reduction in High-Magnification Stereoscopic Measurements Based on Error Equation Calculations, Proceedings of the 41st Annual Meeting of the Electron Microscopy Society of America,. San Francisco Press, Inc., San Francisco,, 704-705.
  • Marx, K.A., Reynolds, T.C. (1982). Spermidine-Condensed PhiX-174 DNA Cleavage by Micrococcal Nuclease: Torus Cleavage Model and Evidence for Unidirectional Circumferential DNA Wrapping,. Proceedings of the National Academy of Science, USA, 79 6484-6488.
  • Ruben, G.C., Marx, K.A., Reynolds, T.C. (1981). Freeze-Fracture Electron Microscopy of Spermidine-Single DNA Double Helices, Proceedings of the 39th Annual Meeting of the Electron Microscopy Society of America,. Claitor's Publishing Co., Atlanta, 440-441.
  • Ruben, G.C., Marx, K.A., Reynolds, T.C., Bailey, G.W. (1981). Stereoscopic Visualization of Spermidine-DNA Torus Structure Prepared by the Freeze-Fracture, Deep-Etch Technique, Proceedings of the 39th Annual Meeting of the Electron Microscopy Society of America. Claitor's Publishing Co., Atlanta,, 438-439.
  • Marx, K.A. (1980). Non-Satellite Repetitive Human DNA Families: Sequence Properties and Evidence for Occurrence in Chimpanzee DNA,. Biochim. Biophysica Acta, 608 232-242.
  • Marx, K.A., Purdom, I.F., Jones, K.W. (1979). Primate Repetitive DNAs: Evidence for New Satellite DNAs and Similarities in Non-Satellite Repetitive DNA Sequence Properties. Chromosoma, 73 153-161.
  • Marx, K.A. (1977). Differential Condensation of Mouse DNA Families in Chromatin: Accessibility to Nuclease Probes,. Biochemical and biophysical research communications, 78 777-783.
  • Marx, K.A., Allen, J.R., Hearst, J.E. (1976). Characterization of the Repetitious Human DNA Families,. Biochim. Biophysica Acta., 425 139-147.
  • Marx, K.A., Allen, J.R., Hearst, J.E. (1976). Chromosomal Localizations by in Situ Hybridization of the Repetitious Human DNA Families and Evidence of Their Satellite DNA Equivalents. Chromosoma, 59 23-42.
  • Marx, K.A. (1975). The Magnitude of Intramolecular DNA Optical Absorbance with Variation in Na+ and GC Base Composition: For Special Application to DNA Reassociation Studies,. Biopolymers, 14 1103-1107.
  • Marx, K.A., Hearst, J.E. (1975). The Two Component Kinetic Analysis Method: Evidence for Two Reassociating Components in Mouse Satellite DNA and D. Ordii HS-beta Satellite DNA,. J. Molecular Biology, 98 355-368.
  • Hearst, J.E., Cech, T.C., Marx, K.A., Rosenfeld, A., Allen, J.R. (1973). Characterization of the Rapidly Renaturing Sequences in the Main CsCl Density Bands of Drosophila, Mouse and the Human DNA, Cold Spring Harbor Symposium Quant.,. Biol., 38 329-339.
  • Marx, K.A. (1973). Physical Characterization and Cytological Localization of the Families of Highly Redundant Human DNA, Ph.D. Thesis,. University of California at Berkeley,, 204.
  • Jones, W.D., Marx, K.A., Croft, S. (1969). Infrared Intensities of the Nitrite Ion in Solid Solution in Potassium Bromide. J. Molecular Spectroscopy, 30 498-505.

Selected Intellectual Property

  • Patent - Kaplan, D.L., Samuelson, L.A., Marx, K.A., Kumar, J., Tripathy, S., Sengupta, S.K., Wiley, B., Cazeca, M.J."Photodetectors Based on Photodynamic Proteins for Image Detection, Image Processing and Dynamic Camouflage Applications," 5,438,192
  • Patent - "Photodetectors Based on Photodynamic Proteins for Image Detection, Image Processing and Dynamic Camouflage Applications," 5,438,192 United States
  • Patent - Marx, K.A., Braunhut, S.J., Zhou, T., Montrone, A."Selective Whole Cell Quartz Crystal Microbalance Biosensors," 7566531
  • Patent - "Selective Whole Cell Quartz Crystal Microbalance Biosensors," 7566531 United States
  • Patent - "Tin Assisted Transfer of Electroplated Metal Structures at Nanoscale,"
  • Patent - Akyurtlu, A., Marx, K.A., Wongkasem, N."Chiral Metamaterials," 8,271,241
  • Patent - "Chiral Metamaterials," 8,271,241
  • Patent - "Novel Acoustic Wave (AW) Sensing Devices Using Living Cells," United States
  • Patent - "Plane Polarized Light Interactions with Repeating Arrays of Structured Conducting Chiral Objects Exhibit Metamaterials Properties- Optical Applications in the Ultraviolet, Visible and Near-Infrared Spectrum," United States
  • Patent - Alva, K.S., Samuelson, L.A., Kumar, J., Tripathy, S.K., Marx, K.A."Method of Forming Water Soluble Electrically Conductive and Optically Active Polymers," 5,994,498
  • Patent - "Method of Forming Water Soluble Electrically Conductive and Optically Active Polymers," 5,994,498 United States
  • Patent - Akkara, J., Kaplan, D.L., Ayyagari, M., Marx, K.A., Kamtekar, S., Pande, R., Kumar, J., Tripathy, S."Chemileuminescence Based Method For Rapid and Sensitive In Situ Detection of Organophosphorus Compounds and Metal Ions," 5,846,753
  • Patent - Akkara, J., Kaplan, D.L., Ayyagari, M., Marx, K.A., Kamtekar, S., Pande, R., Kumar, J., Tripathy, S."Chemileuminescence Based Method For Rapid and Sensitive In Situ Detection of Organophosphorus Compounds and Metal Ions," 5,846,753
  • Patent - "Chemileuminescence Based Method For Rapid and Sensitive In Situ Detection of Organophosphorus Compounds and Metal Ions," 5,846,753
  • Patent - Szafranski, P., Mello, C.M., Sano, T., Marx, K.A., Cantor, C.R., Kaplan, D.L., Smith, C.L."Biotin-Binding Containment Systems," 5,679,533
  • - Szafranski, P., Mello, C.M., Sano, T., Marx, K.A., Cantor, C.R., Kaplan, D.L., Smith, C.L."Biotin-Binding Containment Systems," 5,681,745
  • Patent - "Biotin-Binding Containment Systems," 5,679,533 United States
  • Patent - "Method and System for Separating Nucleic Acid Polymers," 5,440,025 United States
  • - Marx, K.A., Tripathy, S."Method and System for Separating Nucleic Acid Polymers," 5,440,025
  • Patent - Samuelson, L.A., Marx, K.A., Kaplan, D.L., Tripathy, S.K., Kumar, J."Process of Making Langmiur-Blodgett Films Having Photo-Electronic Properties," 5,260,004
  • Patent - "Process of Making Langmiur-Blodgett Films Having Photo-Electronic Properties," 5,260,004 United States
  • Patent - Bruno, F., Akkara, J., Samuelson, L.A., Tripathy, S.K., Mandal, B.K., Kaplan, D.L., Marx, K.A."Method for Synthesizing an Enzyme-Catalyzed Polymerized Monolayer," 5,143,828
  • Patent - "Method for Synthesizing an Enzyme-Catalyzed Polymerized Monolayer," 5,143,828 United States

Selected Contracts, Fellowships, Grants and Sponsored Research

  • Nanomanufacturing of Multifunctional Sensors. The nanocanary-development of a portable cell based biosensor for detection of weaponized agents (1990), Grant - U.S. Army Research
    Mead, J. (Principal), Marx, K.A. (Co-Principal), Braunhut, S.J. (Co-Principal), Project 6, .
  • Development of a 1st Generation Acoustic Wave Biosensor Platform (), Grant - CVIP
    Therrien, J.M. (Principal), Braunhut, S.J. (Principal), Marx, K.A. (Principal)
  • Nanomanufacturing of Multifunctional Sensors (2010), Contract -
    Marx, K.A. (Co-Principal)
  • Nanomanufacturing of Multifunctional Sensors (2007), Grant -
    Marx, K.A. (Principal)
  • Project #06-06990-1 (1994), Sponsored Research - U.S Army Research Office
    Kumar, J., Tripathy, S., Marx, K.A.
  • Project # 06-05869-F (1991), Sponsored Research - Department of the Army, University Research Initiative
    Kumar, J., Marx, K.A., Tripathy, S.