Skip to Main Content

Bridgette Budhlall

Bridgette Budhlall
Professor Bridgette Maria Budhlall, PhDAssociate Professor and Associate Department Chair for Graduate Programs

Research Interests

Synthesis & applications of polymer colloids & soft matter towards stimuli-responsive materials. Emulsion polymers. Photoresist polymers for nanolithography, nanofluidic devices & microcapsules & hybrid nanoparticles for biomedical devices, drug delivery systems & biosensors.

Synthesis and characterization of functional nano-biocolloids:- vesicles, liposomes, colloidosomes, polymersomes and polymer hydrogel microcapsules for drug delivery. Biodegradable shape memory polymers. Anisotropic colloids for directed assembly. Antimicrobial self-healing coatings. Nanostructured polymer colloids for live cell imaging and protein tracking. Light-actuated liquid crystalline polymers.

Education

  • Ph D: Polymer Science and Engineering, (2000), LEHIGH UNIVERSITY, Emulsion Polymers Institute, Department of Chemical Engineering - Bethlehem, PA. USA
    Dissertation/Thesis Title: Grafting reactions in the emulsion polymerization of vinyl acetate using poly(vinyl alcohol) as emulsifier. Thesis Advisor: Prof. Mohamed S. El-Aasser
  • BS: Natural Sciences, (1992), UNIVERSITY OF THE WEST INDIES - St. Augustine, Trinidad & Tobago
    Supporting Area: Analytical Chemistry and Biochemistry

Biography

Dr. Budhlall works on developing smart polymers for nanomedicine applications in the department of Plastics Engineering. Dr. Budhlall also has eight (8) years experience working in industry, most recently at Air Products and Chemicals, Inc. where she worked in the synthesis of latexes for coatings and developed photoresist polymers and immersion fluids for microlithography applications.

Dr. Budhlall is interested in the synthesis of nanostructured materials with controlled morphologies specifically designed to trigger and control motility and assembly with external stimuli. I find it important that my technology can be scaled-up and is of use in a variety of industrial applications ranging from biosensors, chemical sensors and nanofluidic devices, smart coatings and adhesives, drug delivery systems, cellular transport and analysis and biomedical devices.

Awards and Honors

  • Mark and Elisia Saab Endowed Professorship in Sustainable Plastics Engineering (2012), Service, Professional
  • Mark and Elisia Saab Endowed Professorship in Sustainable Plastics Engineering (2011), Service, Professional
  • International Network of Emerging Science & Tech. (INEST) Fellow (2006), Scholarship/Research - Phillip Morris, USA
  • Ken Earhart Award (1998), Scholarship/Research - Emulsion Polymers Institute, Dept. of Chemical Engineering, Lehigh University. PA.
  • Ticona Award (1998), Scholarship/Research - Society for Plastics Engineers (SPE), Materials Research Center, Lehigh University, PA.
  • Henry Mason Award (1996), Scholarship/Research - Department of Chemical Engineering, Lehigh University. PA
  • SRA International Scholarship (1995), Scholarship/Research

Publications

  • Aris, Z.F., Bouldin, R.M., Pelletier, M.G., Gaines, P.C., Budhlall, B., Nagarajan, R. (2017) "Microwave-assisted synthesis and characterization of hydrophilically functionalized polygalacturonic acid," Carbohydrate Polymers 155: pp. 432–439
  • Devre, R.D., Budhlall, B., Barry, C.M. (2016) "Enhancing the colloidal stability and electrical conductivity of single-walled carbon nanotubes dispersed in water," Macromolecular Chemistry and Physics 217:5 pp. 683–700
  • Hassan, S., Anandakathir, R., Sobkowicz Kline, M.J., Budhlall, B. (2016) "Tuning oxygen permeability in azobenzene-containing side-chain liquid crystalline polymers," Polymer Chemistry 7:7 pp. 1452-1460
  • Barry, C.M., Budhlall, B., Nagarajan, R. (2016) "Undergraduate modules for bio-based plastics: educational modules focused on bio-based polymers resulted in good learning outcomes for undergraduate students," Plastics Engineering 72:3 pp. 30
  • Budhlall, B., Garle, A.L. (2015) "Biodegradable shape memory polymer," US Patent US9163114:B2
  • Gu, Z., Budhlall, B., Sun, H., Barry, C.M., Donatelli, A.A., Lohmeier, J. (2013) "A new interdisciplinary engineering course on nanoscale transport phenomena," American Society of Engineering Education (ASEE) Proceedings 23: pp. 1
  • Aris, Z.F., Bouldin, R.M., Nagarajan, R., Budhlall, B., Bavishi, V. (2013) "Hydrophilic modification of water insoluble polysaccharide as surface-active agents," US Patent Appl 13/841,903:
  • Trongsatitkul, T., Budhlall, B. (2013) "Microgels or microcapsules? Role of morphology on the release kinetics of thermoresponsive PNIPAm-co-PEGMa hydrogels," Polymer Chemistry 4:5 pp. 1502–1516
  • Trongsatitkul, T., Budhlall, B. (2013) "Temperature dependence of serum protein adsorption in PEGylated PNIPAm microgels," Colloids and Surfaces B: Biointerfaces 103: pp. 244–252
  • Pal, A.K., Bello, D., Budhlall, B., Rogers, E.J., Milton, D.K. (2012) "Screening for oxidative stress elicited by engineered nanomaterials: evaluation of acellular DCFH assay," Dose-Response 10:3 pp. 308-330
  • Deanin, R.D., Mead, J.L., Wei, M., Budhlall, B. (2012) "Synthetic Resins and Plastics," Springer 12 pp. 623-687
  • Garle, A., Kong, S., Ojha, U., Budhlall, B. (2012) "Thermoresponsive semicrystalline poly (epsilon-caprolactone) networks: exploiting cross-linking with cinnamoyl moieties to design polymers with tunable shape memory," ACS Applied Materials & Interfaces 4:2 pp. 645–657
  • Trongsatitkul, T., Budhlall, B. (2011) "Multicore–shell PNIPAm-co-PEGMa microcapsules for cell encapsulation," Langmuir 27:22 pp. 13468–13480
  • Garle, A., Kong, S., Budhlall, B. (2010) "Design and synthesis of a novel biodegradable polymer for biomedical applications," Polymer Preprints (American Chemical Society, Division of Polymer Chemistry) 51:2 pp. 255
  • Gowda, R., Sun, H., Wang, P., Charmchi, M., Gao, F., Gu, Z., Budhlall, B. (2010) "Effects of particle surface charge, species, concentration, and dispersion method on the thermal conductivity of nanofluids," Advances in Mechanical Engineering 2010:
  • Pardhy, N.P., Budhlall, B. (2010) "Pickering emulsion as a template to synthesize Janus colloids with anisotropy in the surface potential," Langmuir 26:16 pp. 13130–13141
  • Garle, A., Ojha, U., Budhlall, B. (2009) "Combination of ROP and RAFT for synthesis of a novel biodegradable, stimuli responsive P (CL-ran-CCL)-b-PNIPAm-b-P (CL-ran-CCL) triblock copolymer," Polymer Materials Science & Engineering Preprints (ACS) 101: pp. 1221–1222
  • Budhlall, B., Chang, S., Marquez, M., Velev, O.D. (2008) "Microencapsulation via Liquid-Liquid Phase Separation," Polymeric Materials Science & Engineering Preprints (ACS) 99: pp. 835
  • Budhlall, B., Marquez, M., Velev, O.D., others, . (2008) "Microwave, photo-and thermally responsive PNIPAm-gold nanoparticle microgels," Langmuir 24:20 pp. 11959–11966
  • Pardhy, N.P., Budhlall, B. (2008) "Surfactant free, solid stabilized emulsion as a template to synthesize Janus colloidosomes," Polymer Materials Science & Engineering Preprints (ACS) 99: pp. 322
  • Trongsatitkul, T., Budhlall, B. (2008) "Synthesis of Thermoresponsive Copolymers Composed of Poly (ethylene oxide) and Poly (N-isopropylacrylamide) for Cell Encapsulation," Materials Research Society (MRS) Proceedings 1134: pp. 1134–BB08
  • Budhlall, B., Parris, G., Zhang, P., Gao, X., Zarkov, Z., Ross, B., Kaplan, S., Burnett, J. (2005) "High refractive index immersion fluids for 193 nm immersion lithography," Proceedings for the International Society for Optics and Photonics (SPIE): Microlithography 5754: pp. 622–629
  • Broekhuis, R.R., Budhlall, B., Nordquist, A.F. (2004) "Monolith catalytic process for producing sorbitol: Catalyst development and evaluation," Industrial & engineering chemistry research 43:17 pp. 5146–5155
  • Budhlall, B., He, X., Hyder, I., Mehta, S., Parris, G. (2004) "Thermodynamic and kinetic stability of nanobubbles at the water-solid interface: A modeling and AFM study," International SEMATECH 157nm & Immersion Lithography Symposium Proceedings pp. 2–5
  • Budhlall, B., Shaffer, O., Sudol, E., Dimonie, V., El-Aasser, M. (2003) "Atomic force microscopy studies of the film surface characteristics of poly (vinyl acetate) latexes prepared with poly (vinyl alcohol)," Langmuir 19:23 pp. 9968–9972
  • Budhlall, B., Landfester, K., Sudol, E., Dimonie, V., Klein, A., El-Aasser, M. (2003) "Characterization of partially hydrolyzed poly (vinyl alcohol). Effect of poly (vinyl alcohol) molecular architecture on aqueous phase conformation," Macromolecules 36:25 pp. 9477–9484
  • Budhlall, B., Sudol, E., Dimonie, V., Klein, A., El-Aasser, M. (2001) "Role of grafting in the emulsion polymerization of vinyl acetate with poly (vinyl alcohol) as an emulsifier. I. Effect of the degree of blockiness on the kinetics and mechanism of grafting," Journal of Polymer Science Part A: Polymer Chemistry 39:20 pp. 3633–3654
  • Budhlall, B., Landfester, K., Nagy, D., Sudol, E.D., Dimonie, V.L., Sagl, D., Klein, A., El-Aasser, M.S. (2000) "Characterization of partially hydrolyzed poly(vinyl alcohol) I : Sequence distribution of poly(vinyl alcohol) via 13C and 1H-NMR and a reversed-phased gradient elution HPLC technique," 155:1 pp. 63–84
  • Budhlall, B., Landfester, K., Nagy, D., Sudol, E., Dimonie, V., El-Aasser, M. (1999) "Characterization of poly (vinyl alcohol) used in the emulsion polymerization of vinyl acetate," Polymeric Materials Science & Engineering Preprints (ACS) 80: pp. 550–551
  • Budhlall, B. (Lehigh University) (1999) "Grafting reactions in the emulsion polymerization of vinyl acetate using poly (vinyl alcohol) as emulsifier," Ph.D. Dissertation, Lehigh University, PA.

Presentations

  • Melt Blended Phase Separated Polyethylene-b-Polyethylene and Polypropylene Blends for Enhanced Anti-Fouling: Effect of Polyethylene Glycol Chain Length and Surface Density on Protein Adsorption. - Annual Meeting, Society for Biomaterials, April 2017 - Minneapolis, MN
  • PEG Bottle Brush Copolymers for Lysis of Microbial Membrane Mimics by Entropic Templating - Annual Meeting, Society for Biomaterials, April 2017 - Minneapolis, MN
  • "Role of Polymer Architecture on the Kinetics and Mechanisms of Swelling and Drug Release from PNIPAm-co-PEG Hydrogels" - Polymer Preprints (ACS), 2012
  • "Synthesis of Caprolactone-based Shape Memory Polymers with Antimicrobial Properties" - Polymer Preprints (ACS), 2012
  • A New Interdisciplinary Engineering Course at University of Massachusetts Lowell - Nanoscale Transport Phenomena for Manufacturing Nanodevices - Abstracts of Papers, American Institute of Chemical Engineers Annual Meeting, October 2012 - Pittsburgh, PA
  • Microwave-assisted synthesis and characterization of surfactants from renewable resources - Abstracts of Papers, 16th Annual Green Chemistry and Engineering Conference, June 2012 - Washington, DC
  • Doxorubicin Release Kinetics of Polymer-Liposome Nanocapsules - Abstracts of Papers, ACS 87th Colloid and Surface Science Symposium, June 2012 - Baltimore, MD
  • Photostable Bioimaging Probes via Pickering Emulsions - Abstracts of Papers, ACS 87th Colloid and Surface Science Symposium, June 2012 - Baltimore, MD
  • The Role of Nanofluids on the Thermal Conductivity of PNIPAm Microgels - of Papers, ACS 87th Colloid and Surface Science Symposium, June 2012 - Baltimore, MD
  • "A New Interdisciplinary Engineering Course at University of Massachusetts Lowell - Nanoscale Transport Phenomena for Manufacturing Nanodevices - Abstracts of Papers, American Society of Engineering Education (ASEE), Northeast Conference, April 2012 - Lowell, MA
  • Novel Semicrystalline ABA Triblock Shape Memory Polymers for Biomedical Implants - Eastman Medical Innovation Seminar, 2011 - Lowell, MA
  • Enzymatic Synthesis of Polysaccharide-based Biosurfactants - Abstracts of Papers, 15th Annual Green Chemistry and Engineering Conference, June 2011 - Washington, DC
  • Drug Delivery from Poly(N-isopropylacrylamide)-co-poly(ethylene glycol) Microspheres: Effect of Particle Morphology on Release Kinetics - Abstracts of Papers, ACS 86th Colloid and Surface Science Symposium, June 2011 - Montreal, Canada
  • Novel Bioimaging Probes Synthesized by Encapsulation of Quantum Dots in Pickering Emulsions - Abstracts of Papers, ACS 86th Colloid and Surface Science Symposium, June 2011 - Montreal, Canada
  • Surface Active Polymers Derived from Naturally Occurring Polysaccharides - Abstracts of papers, ACS 241st National Meeting, March 2011 - Anaheim, CA
  • Design and Synthesis of a Novel Biodegradable Polymers for Biomedical Applications - Polymer Preprints, 2010
  • Protein Adsorption Resistance of Thermoresponsive PEG-co-PNIPAm Microgels - Abstracts of Papers, ACS 240th National Meeting, August 2010 - Boston, MA
  • Screening for Oxidative Damage of Engineered Nanomaterials: Why the DCFH is of Limited Utility - Abstracts of Papers, Nanotoxicology 2010, June 2010 - Edinburgh Napier University, Craiglockhart Campus, Edinburgh. Scotland
  • Synthesis of Janus Colloids via Pickering Emulsion Templates - International Polymer Colloids Group Conference, 2009 - Il Ciocco, Italy
  • Current Research in Coatings: Use of Nanotechnology to Enhance the Performance of Coatings - New England Society for Coatings Technology, (NESCT) Technical Symposium, 2009 - Sturbridge, MA
  • Combination of ROP and RAFT for Synthesis of a Novel Biodegradable, Stimuli Responsive P(CL-ran-CCL)-b-PNIPAm-b-P(CL-ran-CCL) Triblock Copolymer - Polymer Materials Science & Engineering Preprints, 2009
  • New Developments in Coatings: Smart Polymers & Stimuli Responsive Coatings - Rhode Island College Colloquium, Department of Physical Sciences, Rhode Island College, 2009 - Providence, RI
  • Surfactant Free, Solid Stabilized Emulsion as a Template to Synthesize Janus Colloidosomes - Abstracts of Papers, ACS 83rd Colloid and Surface Science Symposium, June 2009 - New York, NY
  • Synthesis of Thermo-responsive Copolymers composed of Poly(ethylene glycol) and Poly(N-isopropyl acrylamide) for Cell Encapsulation - Proceedings for the International Society for Optics and Photonics (SPIE): Microlithography (MRS) Symposium Proceedings, 2008 - Boston, MA.
  • Microencapsulation via Liquid-Liquid Phase Separation - Polymer Materials Science and Engineering Preprints, August 2008 - Philadelphia, PA.
  • Surfactant Free, Solid Stabilized Emulsion as a Template to Synthesize Janus Colloidosomes - Polymer Materials Science and Engineering Preprints, August 2008 - Philadelphia, PA.
  • Microwave, Photo- & Thermally Responsive PNIPAm - Gold Nanoparticle Microgels - Abstracts of Papers, ACS 82nd Colloid and Surface Science Symposium, June 2008 - Raleigh, NC
  • Light Response of poly-N-isopropylacrylamide Hydrogels Containing Gold Nanoparticles - Abstracts of Papers, 16th Annual NC State University, Undergraduate Research Symposium, (RISE), June 2007 - Raleigh, NC
  • Cell Encapsulation in a Thermoresponsive Polymer Microcapsule - Abstracts of Papers, 15th Annual NC State University, Undergraduate Research Symposium, (RISE), June 2006 - Raleigh, NC
  • Responsive Polymer Microcapsules Prepared by Liquid-Liquid Phase Separation - Abstracts of Papers, ACS 80th Colloid and Surface Science Symposium, June 2006 - Boulder, CO
  • High Refractive Index Immersion Fluids for 193nm Immersion Lithography - Proceedings for the International Society for Optics and Photonics (SPIE): Microlithography, May 2005 - Santa Clara, CA.
  • Wetting, Nanobubbles, and Interfacial Dynamics near the Liquid-Solid Interface - 13th International Conference on the Discrete Simulation of Fluid Dynamics (DSFD 2004), August 2004 - Cambridge, MA
  • New Immersion Fluids for 193nm Immersion Lithography - International SEMATECH 157nm & Immersion Lithography Symposium, August 2004 - Vancouver, Canada
  • Thermodynamic and Kinetic Study of Nanobubbles at the Liquid-Solid Interface: A modeling and AFM Study - International SEMATECH 157nm & Immersion Lithography Symposium, August 2004 - Vancouver, Canada
  • High-throughput monolithic catalyst testing: A fully automated approach to process optimization and catalyst life testing - Catalyst Society of Metropolitan New York Spring Symposium, March 2003 - New York, NY
  • Fundamental Study of Surfactants in Emulsion Polymerization: Effect of Surfactant type on Particle Size - Gordon Research Conference, Polymer Colloids, July 2001 - Tilton, NH
  • Role of Grafting in the Emulsion Polymerization of Vinyl Acetate I: Effect of Degree of Poly(vinyl alcohol) Blockiness on the Kinetics and Mechanism of Grafting - ACS 74th Colloid and Surface Science Symposium, June 2000 - Bethlehem, PA
  • Characterization of Partially Hydrolyzed Poly(vinyl alcohol) - Polymer Materials Science and Engineering, 1999 - Anaheim, CA
  • Characterization of Poly(vinyl alcohol) via 13C and 1H-NMR - Ticona Award Meeting of the Society of Plastic Engineers (SPE), October 1998 - Bethlehem, PA
  • Characterization of Poly(vinyl alcohol) - ACS 3rd National Graduate Polymer Conference, University of Akron, June 1998 - Akron, OH

Intellectual Property

  • Patent - Budhlall, B., Garle, A.L."Biodegradable shape memory polymers," US Patent 9,163,114 B2 Patent Cooperation Treaty
  • Patent - Aris, Z., Bouldin, R., Nagarajan, R., Budhlall, B."Hydrophilic modification of water insoluble polysaccharide as surface-active agents," US Patent 6,161,2909 United States
  • Patent - Zhang, P., Budhlall, B.M., Parris, G.E., Cox, L."Immersion lithography fluids," US Patent 8,007,986 B2 United States
  • Patent - Zhang, P., Budhlall, B.M., Parris, G.E., Cox, L."Immersion lithography fluids," US Patent 7,879,531 B2 United States

Contracts, Fellowships, Grants and Sponsored Research

  • Directed Assembly of Colloids for Nanomanufacturing Hierarchically Ordered Electronic Films (2015), Grant - National Science Foundation
    Sobkowicz Kline, M.J., Budhlall, B.
  • Polymer Films for Chemical Sensors (2014), Grant - Raytheon
    Budhlall, B. (Principal)
  • Antimicrobial Shape Memory Polymers for Wound Dressings (), Grant - Biosurfaces, Inc
    Budhlall, B. (Principal)
  • TUES: Biobased Plastics for a Sustainable Future: Undergraduate Educational Modules for the Engineering Curricula (2013), Grant - National Science Foundation
    Budhlall, B. (Principal), Barry, C. (Co-Principal), Nagarajan, R. (Co-Principal)
  • NUE: Interdisciplinary Course - Nanoscale Transport Phenomena for Manufacturing N (2010), Grant -
    Budhlall, B. (Co-Principal)
  • Biocompatibility of Poly(episilon-caprolactone) Shape Memory Polymers: In Vivo and In Vitro Studies (2012), Grant - Massachusetts Technology Collaborative
    Budhlall, B. (Principal)
  • Dandeneau Endowed Professorship in Sustainable Plastics Engineering (2012), Grant - Department of Plastics Engineering
    Budhlall, B. (Principal)
  • Large Scale Synthesis and Biodegradation of Poly(_-caprolactone) Shape Memory Polymers (2012), Grant - Corporate Ventures and Intellectual Property Office
    Budhlall, B. (Principal)
  • MRI: Acquisition of a Nanoimprint Lithography System for Nanomanufacturing and Nano/Micro Fabrication (), Grant - National Science Foundation
    Budhlall, B., Sun, H. (Principal), Barry, C. (Co-Principal), Gu, Z. (Co-Principal), Wang, X. (Co-Principal)
  • NUE: Interdisciplinary Course - Nanoscale Transport Phenomena for Manufacturing Nanodevices (2012), Grant - National Science Foundation
    Budhlall, B. (Co-Principal), Gu, Z. (Principal), Sun, H. (Co-Principal), Barry, C. (Co-Principal), Donatelli, A. (Co-Principal)
  • Nanomanufacturing Center For Excellence (2011), Sponsored Research -
    Budhlall, B. (Principal)
  • Funding For Various Initiatives (2009), -
    Budhlall, B. (Principal)
  • Biodegradable Shape Memory Polymers (), Grant - UML Provost Office Seed Grant and Joseph P. Healey Endowment
    Budhlall, B. (Principal)
  • Anisotropic Nanocolloids as Biosensors for Live Cells (), Grant - Massachusetts Technology Collaborative
    Budhlall, B. (Principal)
  • DNA-directed Assembly of Janus Nanocolloids (), Grant - Center for High-Rate Nanomanufacturing
    Budhlall, B. (Principal)
  • PVC Resin Formulation for GEM4000 Sensor Cards (), Grant - Instrumentation Laboratories
    Budhlall, B. (Principal), Orroth, S. (Co-Principal)