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Yi-Ning (Winnie) Wu

Yi-Ning (Winnie) Wu is an Assistant Professor in the Department of Physical Therapy at UMass Lowell.
Yi-Ning WuAssociate Professor, Scientific Lead in Physiological Measurement, NERVE Center

Research Interests

Understanding motor control/adaptation and muscle adaption due to injury and intervention, Technology-based rehabilitation for Post-concussion syndrome


  • Ph D: Institute of Biomedical Engineering, (2007), National Cheng Kung University - Tainan, Taiwan
    Dissertation/Thesis Title: Quantification of Abnormal Muscle Tone in Animal Model and in Clinical Setting.
  • BS: Department of Physical Therapy, (2000), National Cheng Kung University - Tainan, Taiwan

Selected Awards and Honors

  • 2015 Faculty Award for Teaching Excellence (2015), Teaching - University of Massachusetts Lowell
  • Sarah Baskin Award for Excellence in Research, 1st place (2010), Scholarship/Research - Rehabilitation Institute of Chicago
  • Switzer Fellowship Award (2009), Scholarship/Research - National Institute of Disability Research and Rehabilitation (NIDRR), Department of Education
  • Student Travel Scholarship (2007), Scholarship/Research - American Academy for Cerebral Palsy and Developmental Medicine
  • Li Foundation Fellow (2005), Scholarship/Research - Li Foundation
  • Podium Paper Award (2003), Scholarship/Research - Biomedical Engineerinig Society
  • Design of Associative Devices for the Disabled (2002) - TiC100

Selected Publications

  • Xu, D., Wu, Y., Gaebler-Spira, D., Gao, F., Clegg, N.J., Delgado, M.R., Zhang, L.Q. (2020). Neural and non-neural contributions to ankle spasticity in children with cerebral palsy. Developmental medicine and child neurology.
  • Wu, Y., Gravel, J., Chatiwala, N., Enis, T., Stark, C., Cantu, R. (2018). Effects of Electrical Stimulation in People with Post-Concussion Syndromes: A Pilot Study. Health, 10(4) 381-395.
  • Kastroba, B., Wu, Y., Kao, P.C., Stark, C., Yen, S., Roh, J. (2018). Muscle activation pattern during self-propelled treadmill walking. Journal of Physical Therapy Science, 30(8) 1069-1072.
  • Zhu, Y., Wu, Y., Su, H., Hu, S., Cao, T., Zhang, J., Cao, Y. (2017). Identify Non-fatigue State to Fatigue State Using Causality Measure During Game Play (pp. 581--588).
  • Lydakis, A., Meng, Y., Munroe, C., Wu, Y., Begum, M. (2017). A learning-based agent for home neurorehabilitation. IEEE ... International Conference on Rehabilitation Robotics : [proceedings], 2017 1233-1238.
  • Meng, Y., Munroe, C., Wu, Y., Begum, M. (2016). A learning from demonstration framework to promote home-based neuromotor rehabilitation (pp. 1126--1131).
  • Ren, Y., Wu, Y., Yang, C.Y., Xu, T., Harvey, R., Zhang, L.Q. (2016). Developing a wearable ankle rehabilitation robotic device for in-bed acute stroke rehabilitation. IEEE Trans Neural Syst Rehabil Eng.
  • Yen, S.C., Corkery, M.B., Donohoe, A., Grogan, M., Wu, Y. (2016). Feedback and Feedforward Control During Walking in Individuals With Chronic Ankle Instability. J Orthop Sports Phys Ther, 46(9) 775-83.
  • Chen, K., Wu, Y., Ren, Y., Liu, L., Gaebler-Spira, D., Tankard, K., Lee, J., Song, W., Wang, M., Zhang, L.Q. (2016). Home-based versus laboratory-based robotic ankle training for children with cerebral palsy: A pilot randomized comparative trial. Arch Phys Med Rehabil.
  • Wu, Y., Ren, Y., Tsai, L.C., Gao, F., Zhang, L.Q. (2016). In vivo simultaneous evaluations of sarcomere imaging and muscle fiber tension. J Biomech, 49(5) 797-801.
  • Wu, Y., Hallbourg, K.W., Collins, S.M. (2015). Changes of general fitness and muscle properties following police cadet training. J Phys Ther Sci, 27(9) 2783-6.
  • Wu, Y., Saliu, V., Donoghue, N., Donoghue, J., Kerman, K. (2013). A Home-based massed practice system for pediatric neurorehabilitation. Journal of Accessibility and Design for All, 3(2) 95-117.
  • Ren, Y., Kang, S.H., Park, H.S., Wu, Y., Zhang, L.Q. (2013). Developing a multi-joint upper limb exoskeleton robot for diagnosis, therapy, and outcome evaluation in neurorehabilitation. IEEE Trans Neural Syst Rehabil Eng, 21(3) 490-9.
  • Drobyshevsky, A., Derrick, M., Luo, K., Zhang, L.Q., Wu, Y., Takada, S.H., Yu, L., Tan, S. (2012). Near-term fetal hypoxia-ischemia in rabbits: MRI can predict muscle tone abnormalities and deep brain injury. Stroke, 43(10) 2757-63.
  • Wu, Y., Wilcox, B., Donoghue, J.P., Crisco, J., Kerman, K.L. (2012). The impact of massed practice on children with hemiplegic cerebral palsy: Pilot study of home-based toy play therapy. Journal of medical and biological engineering, 32(5) 331-342.
  • Zhao, H., Wu, Y., Hwang, M., Ren, Y., Gao, F., Gaebler-Spira, D., Zhang, L.Q. (2011). Changes of calf muscle-tendon biomechanical properties induced by passive-stretching and active-movement training in children with cerebral palsy. J Appl Physiol (1985), 111(2) 435-42.
  • Wu, Y., Hwang, M., Ren, Y., Gaebler-Spira, D., Zhang, L.Q. (2011). Combined passive stretching and active movement rehabilitation of lower-limb impairments in children with cerebral palsy using a portable robot. Neurorehabil Neural Repair, 25(4) 378-85.
  • Peng, Q., Park, H.S., Shah, P., Wilson, N., Ren, Y., Wu, Y., Liu, J., Gaebler-Spira, D.J., Zhang, L.Q. (2011). Quantitative evaluations of ankle spasticity and stiffness in neurological disorders using manual spasticity evaluator. J Rehabil Res Dev, 48(4) 473-81.
  • Khan, N., Levin, S.D., Domont, Z.B., Wu, Y., Ren, Y., Zhang, L.Q. (2011). Strain effects of placing an arthroscopic portal through the subscapularis tendon. J Shoulder Elbow Surg, 20(1) 33-8.
  • Wu, Y., Ren, Y., Goldsmith, A., Gaebler, D., Liu, S.Q., Zhang, L.Q. (2010). Characterization of spasticity in cerebral palsy: dependence of catch angle on velocity. Dev Med Child Neurol, 52(6) 563-9.
  • Wu, Y., Ren, Y., Hwang, M., Gaebler-Spira, D.J., Zhang, L.Q. (2010). Efficacy of robotic rehabilitation of ankle impairments in children with cerebral palsy. Conf Proc IEEE Eng Med Biol Soc, 2010 4481-4.
  • Wu, Y., Ren, Y., Zhang, L.Q. (2010). In vivo sarcomere imaging and fiber tension measurements. Conf Proc IEEE Eng Med Biol Soc, 2010 1986-9.
  • Hsieh, T.H., Tsai, J.Y., Wu, Y., Hwang, I.S., Chen, T.I., Chen, J.J. (2010). Time course quantification of spastic hypertonia following spinal hemisection in rats. Neuroscience, 167(1) 185-98.
  • Zhao, H., Wu, Y., Liu, J., Ren, Y., Gaebler-Spira, D.J., Zhang, L.Q. (2009). Changes of calf muscle-tendon properties due to stretching and active movement of children with cerebral palsy–a pilot study. Conf Proc IEEE Eng Med Biol Soc, 2009 5287-90.
  • Wu, Y., Chen, J.J., Zhang, L.Q., Hyland, B.I. (2009). Regulation of hind-limb tone by adenosine A2A receptor in rats. Neuroscience, 159(4) 1408-13.
  • Zhao, H., Ren, Y., Wu, Y., Liu, S.Q., Zhang, L.Q. (2009). Ultrasonic evaluations of Achilles tendon mechanical properties poststroke. J Appl Physiol (1985), 106(3) 843-9.
  • Lee, H.M., Chen, J.J., Wu, Y., Wang, Y.L., Huang, S.C., Piotrkiewicz, M. (2008). Time course analysis of the effects of botulinum toxin type a on elbow spasticity based on biomechanic and electromyographic parameters. Arch Phys Med Rehabil, 89(4) 692-9.
  • Ren, Y., Park, H., Wu, Y., Geiger, F., Zhang, L.Q. (2008). Training for knee injury prevention using a pivoting elliptical machine. Conf Proc IEEE Eng Med Biol Soc, 2008 727-30.
  • Wu, Y., Hyland, B.I., Chen, J.J. (2007). Biomechanical and electromyogram characterization of neuroleptic-induced rigidity in the rat. Neuroscience, 147(1) 183-96.
  • Wu, Y., Park, H.S., Ren, Y., Gaebler-Spira, D., Chen, J.J., Zhang, L.Q. (2006). Measurement of elbow spasticity in stroke patients using a manual spasticity evaluator. Conf Proc IEEE Eng Med Biol Soc, 1 3974-7.
  • Chen, J.J., Wu, Y., Huang, S.C., Lee, H.M., Wang, Y.L. (2005). The use of a portable muscle tone measurement device to measure the effects of botulinum toxin type a on elbow flexor spasticity. Arch Phys Med Rehabil, 86(8) 1655-60.
  • Lin, S.I., Tsai, T.T., Lee, I.H., Wu, Y. (2002). Perception of unsteadiness in patients with dizziness: association with handicap and imbalance. J Biomed Sci, 9(5) 428-35.

Selected Intellectual Property

  • Patent - Zhang, L., Wu, Y., Ren, Y."System and Method of Microscopic Imaging and Soft Tissue Tension Measurements," 7998094 United States

Selected Contracts, Fellowships, Grants and Sponsored Research

  • Towards Biometric Input for Multi-Agent Adaptive Human-Robot Collaboration (2018), Grant - UML-WPI Collaborative Seed Funding Initiative
    Wu, Y. (Co-Investigator), Yanco, H. (Co-Principal), Solovey, E. (Principal)
  • Feasibility of an Artificially Intelligent Home-Based Rehabilitation System for Children with Cerebral Palsy using Wearable Technologies (2016), Grant - University of Massachusetts Lowell
    Wu, Y. (Principal), Begum, M. (Co-Principal)
  • Home-based rehabilitation for children with cerebral palsy using wearable technologies (2016), Grant - IEEE Robotics and Automation Society Special Interest Group on Humanitarian Technology (RAS-SIGHT)
    Wu, Y. (Co-Principal), Begum, M. (Principal)
  • EEL: a novel approach for home monitoring of upper extremity activities using combined EMG, EKG and Limbs motion (2014), Grant - University of Massachusetts Lowell
    Wu, Y. (Principal), Collins, S.M. (Co-Investigator)
  • EV: CLIN 103 – EX5:Mitigating Impacts of Explosive Ordnance Disposal (EOD) Personal Protective Equipment (PPE) on Wearer Performance via Exoskeleton Integration (2020), Sponsored Research - U.S. Army Combat Capabilities Development Command (CCDC) Soldier Center
    Wu, Y. (Principal), Norton, A. (Co-Principal), Yanco, H. (Co-Principal)
  • The effects of the cervical electrical stimulation and aerobic exercise on people with post-concussion syndrome (2016), Sponsored Research - Emerson Hospital
    Wu, Y. (Principal)
  • Method and technology assessment literature review (2014), Contract - Biogen Idec
    Wu, Y. (Principal)
  • Pilot multi-center evaluations of reflex and nonreflex changes in cerebral palsy (2013), Sponsored Research - AACPDM
    Wu, Y. (Principal)
  • The effectiveness of intelligent-stretching followed by Active movement in children with cerebral palsy (2009), Fellowship - National Institute on Disability and Rehabilitation Research, Department of Education
    Wu, Y. (Principal)