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Carl W. Lawton

Carl Lawton
Carl W. LawtonAssociate Professor, Program Coordinator
  • CollegeFrancis College of Engineering
  • DepartmentChemical Engineering
  • Phone(978) 934-3158
  • EmailCarl_Lawton@uml.edu

Research Interests

Development of advanced materials with unique electronic, optical, structural, or interfacial properties; development of efficient manufacturing processes for the biotechnology industry.

Education

  • Ph D: Civil and Environmental Engineering, (1992), Michigan State University - Michigan, US
    Supporting Area: Transportation and Traffic Engineering
  • Ph D: Chemical Engineering, (1990), University of Connecticut - Storrs, CT
    Dissertation/Thesis Title: Biological Production of Nonlinear Optical Materials
  • MS: Chemical Engineering, (1985), University of Connecticut - Storrs, CT
  • MS: Microbiology, (1977), University of Connecticut - Storrs, CT
  • BS: Microbiology, (1972), Purdue University - West Lafayette, IN

Awards and Honors

  • State of Connecticut High Technology Fellowship (1984)

Publications

  • Lee, H., Lawton, C.W., Na, Y., Yoon, S. (2013) "Robustness of chemometrics-based feature selection methods in early cancer detection and biomarker discovery," Statistical Applications in Genetics and Molecular Biology 12:2 pp. 207-223
  • Nicolosi, R.J., Wilson, T.A., Lawton, C.W., Handelman, G.J. (2001) "Dietary effects on cardiovascular disease risk factors: Beyond saturated fatty acids and cholesterol," Journal of the American College of Nutrition 20:5 pp. 421-427
  • Wilson, T.A., Ausman, L.M., Lawton, C.W., Hegsted, D.M., Nicolosi, R.J. (2000) "Comparative cholesterol lowering properties of vegetable oils: Beyond fatty acids," Journal of the American College of Nutrition 19:5 pp. 601-607
  • Wilson, T.A., Nicolosi, R.J., Lawton, C.W., Babiak, J. (1999) "Gender differences in response to a hypercholesterolemic diet in hamsters: Effects on plasma lipoprotein cholesterol concentrations and early aortic atherosclerosis," Atherosclerosis 146:1 pp. 83-91
  • Lawton, C.W., Swartz, R. (1999) "Process for the Purification of Acarbose, Pharmaceutical Composition Containing Same and its Use for the Treatment of Diabetes,"
  • Nicolosi, R.J., Lawton, C.W., Wilson, T.A. (1999) "Vitamin E reduces plasma low density lipoprotein cholesterol, LDL oxidation, and early aortic atherosclerosis compared with black tea in hypercholesterolemic hamsters," Nutrition Research 19:8 pp. 1201-1214
  • Nicolosi, R.J., Wilson, T.A., Lawton, C.W., Rogers, E.J., Wiseman, S.A., Tijburg, L.B., Kritchevsky, D. (1998) "The greater atherogenicity of nonpurified diets versus semipurified diets in hamsters is mediated via differences in plasma lipoprotein cholesterol distribution, ldl oxidative susceptibility, and plasma α-tocopherol concentration," Journal of Nutritional Biochemistry 9:10 pp. 591-597
  • Baclaski, J., Klei, H., Talbot, D., Lawton, C.W. (1991) "Construction of Repetitive Polypeptides for Optical Applications," Abstracts of Papers of the American Chemical Society 202:
  • Bunning, T.J., Lawton, C.W., Klei, H.E., Sundstrom, D.W. (1991) "Physical Property Improvements of a Pellicular Biocatalyst," Bioprocess Engineering 7:1-2

Intellectual Property

  • Patent - Lawton, C.W.""A Process for the Purification of Acarbose"," 99/07720
  • Patent - Lawton, C.W.""Biomolecular Synthesis of Quantum Dot Composites"," US Patent # 6,350,515 United States
  • Patent - Lawton, C.W.""Biomolecular Synthesis of Quantum Dot Compositions"," 5,985,353 United States
  • Patent - Lawton, C.W.""On-Axis spatial light modulators and methods of use"," 5,872,648 United States
  • Patent - Lawton, C., Swartz, R."A Process for the Purification of Acarboseo," 99/07720
  • Patent - Lawton, C.W., Conroy, S."Biomolecular Synthesis of Quantum Dot Composites," 6,350,515 United States
  • Patent - Lawton, C.W."Biomolecular Synthesis of Quantum Dot Compositions," 5,985,353 United States
  • Patent - Sanchez, J.D., Pommet, D., Fiddy, M., Lawton, C."On-Axis spatial light modulators and methods of use," 5,872,648 United States
  • - Lawton, C.W., Nicolosi, R.J., McCarthy, S."Refined Vegetable Oils and Extracts Thereof," 6,197,357 United States
  • Patent - Lawton, C.W."ñRefined Vegetable Oils and Extracts Thereofî," # 6,197,357 United States

Contracts, Fellowships, Grants and Sponsored Research

  • (), Grant -
    Lawton, C.
  • Purification Process Development for the Capture and Purification of MU1140 from (2014), -
    Lawton, C.W. (Principal)
  • High Stable Human Plasma Butyrylcholinesterase for Intra-Muscular Delivery (2013), Contract - Defense Threat Reduction Agency
    Lawton, C.W. (Co-Principal)
  • Preparation of E. coli Lysate (2012), -
    Lawton, C.W. (Principal)
  • Preparation of IgG from HEK 293 I (2013), -
    Lawton, C.W. (Principal)
  • Purification of StxB-cys (2012), -
    Lawton, C.W. (Principal)
  • Purification Process Development for the Capture and Purification of MU1140 from (2013), -
    Lawton, C.W. (Principal)
  • Production of E. coli Cell Paste II (2013), -
    Lawton, C.W. (Principal)
  • Mixing Trial I (2012), -
    Lawton, C.W. (Principal)
  • Capture Step of "FluBlok" with high capacity membrane adsorbers (2012), -
    Lawton, C.W. (Principal)
  • New Faculty Position in Biomanufacturing Science and Engineering (2008), Grant -
    Lawton, C.W. (Principal)
  • MicroFluidizer Use (2011), -
    Lawton, C.W. (Principal)
  • Production of E coli Cell Paste (2012), -
    Lawton, C.W. (Principal)
  • Developing Emergency Evacuation Plans for Nuclear Power Plants based on Large Scale Transportation Network Simulation (2011), - National Nuclear Security Administration
    Laston, C., Xie, Y., Gartner, N.
  • Performance Enhancement of Traffic Operations Centers (2009), Grant - MassDOT Highway Divison
    Lawton, C.W., Gartner, N.
  • Production of Protein StxB/Cys (2009), -
    Lawton, C.W. (Principal)
  • Development of a High-Capacity and Cost-effective Manufacturing Process for Chlor (2011), - U.S. Department of the Army
    Lawton, C.W. (Principal)
  • Bioengineering of Saccharomyces cerevisiae for the Selective Production of beta-Penine (2011), - Naval Air Warfare Center
    Lawton, C.W. (Principal)
  • Xylan to Itaconic Acid (2010), Contract - U.S. Department of Agriculture
    Lawton, C.W. (Principal)
  • Production of Protein STxB/Cys (2009), -
    Lawton, C.W. (Principal)
  • Shiga Scale-up (2010), -
    Lawton, C.W. (Principal)
  • Fermentation Process Development With Single-Use Bioreactors (2009), -
    Lawton, C.W. (Principal)
  • Interactive TMC Decision Support Tool Combining Simulation and Optimization (2008), Grant - UMass-University Transportation Center
    Lawton, C.W., Gartner, N., Jones, L.
  • MicroFluidizer Use (2008), -
    Lawton, C.W. (Principal)
  • Optimization and Scale-up of Natrix Q Membrane (2009), -
    Lawton, C.W. (Principal)
  • Recombinant Antibody Productivity and Quality as a Function of Media Composition (2009), -
    Lawton, C.W. (Principal)
  • Ozone-based Clean-in-place (CIP) of Bioreactors (2009), -
    Lawton, C.W. (Principal)
  • GSP Production of Shiga StxB-cys-2 (2008), Grant -
    Lawton, C.W. (Principal)
  • Traffic Flow Characteristics on Arterial Streets and their Impact on Capacity and Level of Service (2005), Grant - University Transportation Center, Region 1, U.S. Department of Transportation
    Lawton, C.W., Gartner, N.
  • Implementation of a Web-Based Course on Traffic Principles for Intelligent Transportation Systems (2003), Grant - University Transportation Center, Region 1, U.S. Department of Transportation
    Lawton, C.W.
  • Development of a Web-Based Course on Traffic Principles for Intelligent Transportation Systems (2001), Grant - University Transportation Center, Region 1, U.S. Department of Transportatino
    Lawton, C.W.
  • Development of Modules for a web based ITS Training and Education course (1999), Grant - University of Maryland
    Lawton, C.W.
  • Evaluation of the Massachusetts Motorist Assistance Program (1995), Grant - Massachusetts Highway Department
    Lawton, C.W., Gartner, N.
  • Real Time Traffic Adaptive Signal Control System (1993), Grant - U.S. Department of Transportation, Federal Highway Administration
    Lawton, C.W., Gartner, N.
  • Development and Evaluation of Advanced Traffic Control Strategiesion (1993), Grant - Raytheon Company
    Lawton, C.W.
  • Project # 05-05744 (1990), Sponsored Research - K-Tec Corporation
    Kumar, J., Lawton, C.W. (Supporting)