04/03/2024
By Mark Tries
The Biomedical Engineering and Biotechnology Program invites you to attend a dissertation proposal defense by Nada Alsufyani on “Quantification of Biological Response to Low Dose Ionizing Radiation: A Dose-Response Modeling Approach.”
Ph.D. Candidate: Nada Alsufyani
Date: April 11, 2024
Time: 12:30 to 2 p.m.
Location: This will be a virtual defense via Zoom. Those interested in attending should contact Nada_Alsufyani@student.uml.edu and committee member Mark_Tries@uml.edu at least 24 hours prior to the proposal defense to request access to the meeting.
Committee
- Chair Mark Tries, Ph.D., Associate Professor, Physics and Applied Physics
- Romy Guthier, Ph.D., Assistant Professor, Physics and Applied Physics
- Marian Jandel, Ph.D., Assistant Professor, Physics and Applied Physics
Abstract:
This research proposal addresses the critical need for an enhanced understanding of the dose-response relationship for low-dose ionizing radiation exposures. Current models, predominantly reliant on the Linear No-Threshold (LNT) extrapolation from high-dose scenarios, lack comprehensive insights into potential biological responses at low-doses. Leveraging recent epidemiological and biological studies, this proposed research aims to develop and validate a novel dose-response model that integrates both types of evidence. The methodology involves a comprehensive comparative analysis against existing models, followed by identifying strengths and limitations. Recommendations for model enhancements, including potential new study designs, will guide the refinement of predictive capabilities. The anticipated outcomes are intended to advance our understanding of low-dose ionizing radiation effects, inform risk assessment practices, and contribute to developing more accurate radiation protection regulations.
All interested persons are welcome to attend.