This graduate course is designed to study the molecular aspects of disease. Applications and techniques utilized in the field of molecular pathology are emphasized. This course is intended to provide students with information required to understand the increasing role of molecular pathology in the daily practice and management of chronic disease in medicine. Major emphasis on strength and limitations of clinical diagnostics technologies and their utilization in these applications are presented. This course will also provide a review of current molecular pathology literature and principles as they relate to specific organ systems.