This course will focus on protein dynamics where students will gain facility with thermodynamics of protein folding/misfolding, catalysis, kinetics and binding equilibria as they apply to proteins and other molecules in biological systems. The central theme of this course is that living systems can be understood in terms of the fundamental principles defining the structure and energetics of biological molecules. Attention will be given to quantitative aspects of enzyme kinetics and molecular binding. Examples of how these principles apply to the understanding and treatment of human disease will be discussed.
Pre-Req: 81.419 Biochemistry.