Atherosclerosis; Lipoprotein; Inflammation, antioxidants, oxidative stress, cardiovascular diseases, reproductive medicine, fertility; In vitro fertilization, laboratory medicine, and analytical method validation.
Atherosclerosis is a chronic disease in which modified lipid derivatives and cell infiltrations are mediated through a complex inflammatory process leading to plaque and tissue build up within the coronary arteries. This is the underlying cause of the majority of clinical cardiovascular events, which is the leading cause of death in the USA and around the world. Our Research Group focuses on the understanding of the role of lipids and its metabolites on atherosclerosis and lipoproteins metabolism. The group is also interested in obesity studies and the involvement of adipose biomarkers on atherosclerosis and other related chronic disorder. In addition the group is interested in studies on the role of indoor air pollution. The group research lab performs basic research experiments using cell culture, animal models and clinical studies. These studies involve dietary, antioxidants and therapeutic supplements targeting specific pathways of inflammation and oxidative stress. We are also interested in new clinical laboratory method development and validation.