This course covers the physics and electrical engineering aspects of how signals are acquired from which images will be formed, and the principal methods by which the signals are processed to form useful medical diagnostic images. Modalities studied include: x-rays, ultra-sound, computed tomography, and magnetic resonance imaging. The principles of signal processing via Fourier transform will be reviewed. Noise and other artifacts that degrade the medical diagnostic of images are considered. MATLAB is heavily used in simulation and verification.