Sarah Harcum

Sarah Harcum

Professor in Bioengineering, Clemson University


Sarah Harcum is a Professor in Bioengineering at Clemson University. Harcum has extensive experience in the scale-up of biopharmaceuticals from bacterial and mammalian cell systems. 

Harcum has a BSE in Engineering Science – Bioengineering from the University of Michigan, a MS in Chemical Engineering from Colorado State University, and a PhD in Chemical Engineering from the University of Maryland. 

Harcum was a Staff Fellow and Certified Product Reviewer in the Division of Monoclonal Antibodies within the Center for Biologics Evaluation and Research (CBER) at the US Food and Drug Administration (FDA). She was a faculty member at New Mexico State University in Chemical Engineering and the Molecular Biology Program prior to moving to Clemson in 2002. 

Harcum’s primary research areas, cell culture and recombinant protein production (biomanufacturing), focus on reducing production costs by better understanding cells in the bioreactor environment. In addition to the most common organisms used in biomanufacturing, Escherichia coli and Chinese hamster ovary (CHO) cells, Harcum works on cell lines with biomanufacturing potential such as induced pluripotent stem (iPS) cells.