03/08/2023
By Mufeed Mahd

The College of Engineering, Biomedical and Biotechnology Graduate Program, invites you to attend a doctoral dissertation defense by Senait Haileselassie on "Low Cost, Low Foot Print, Fast Processing POC Glucose Meter."

Candidate Name: Senait Haileselassie
Degree Ph.D.
Date: Wednesday, March 22, 2023
Time: 1-2:30 p.m.
Location: Ball Hall 301

Committee:

  • Advisor Prof. Mufeed MahD, ECE
  • Prof. Samson Milshtein, ECE
  • Prof. Bryan Buchholz, BME

Brief Abstract:

According to the National diabetes statistics, 37.3 million people of the U.S. population had diagnosed diabetes and the cost estimated $237 billion is spent each year on direct medical costs and another $90 billion on reduced productivity.

Diabetes can cause long-term complications like heart disease, kidney failure, nerve diseases and blindness if not treated the right way. To reduce the risk of complication and to extend the life expectancy of the patients, tight glycemic control is in order. This PhD research meant to design an easy to use and a reliable device for continuous blood sugar monitoring to inject an accurate dose of insulin when needed.

A noninvasive blood glucose measuring device is proposed, implemented, and tested. The device belongs to the class of continuous glucose monitor with cloud connectivity. The final product is meant to be POC, easy to operate, equipped with voice interface & color-coded lights, sturdy, and provides reliable readings under different testing conditions (vibrations and noises, temperature variation, etc.).

The device takes a burst of measurements, employs advanced statistical and digital signal processing to output impedance frequency spectrum. Signal processing includes but not limited to: correlation coefficient, NRMSE (normalized root mean squared error), MAPE (mean absolute percent error), and discrete Fourier transform (DFT). Device sensitivity and selectivity were tested and proved accurate. The designed device was calibrated versus three commercially available blood glucose measuring devices. The device used glucose dextrose in different solution mixtures in composition and concentration.