11/07/2022
By Kwok Fan Chow

The Kennedy College of Science, Department of Chemistry, invites you to attend a dissertation defense by Farkhad Maksudov entitled “Multiscale Computational and Theoretical Exploration of Mechanical Properties of Fibrin Polymers.” The defense will be held in Olney 520 (North Campus) on Tuesday, Nov. 22 at 10 a.m.

Committee Chair: Prof. Valeri Barsegov, Department of Chemistry, University of Massachusetts Lowell

Committee Members:

  • Prof. Kenneth A. Marx, Department of Chemistry, University of Massachusetts Lowell
  • Prof. Jayant Kumar, Department of Physics and Applied Physics, University of Massachusetts Lowell
  • Prof. Victor Podolskiy, Department of Physics and Applied Physics, University of Massachusetts Lowell

Abstract:

The overarching goal of this work is to understand the molecular origin of the mechanical properties of a unique biopolymer, fibrin. More specifically, this work addresses the response of fibrin to tension on different levels of organization — from fibrin protofibrils, to a single fibrin fibers and to fibrin networks — combining high-performance computing and theoretical modeling applied to interpret experimental biophysical measurements. This knowledge is necessary to understand the role of fibrin network scaffolds in hemostasis and thrombosis.

All interested students and faculty members are invited to attend.