04/06/2022
By Erno Sajo

The Kennedy College of Sciences, Department of Physics and Applied Physics, Medical Physics Program, invites you to attend a Master's thesis defense by Michele Moreau on "Investigating the Use of Smart Radiotherapy Biomaterials for Cancer Therapy and Imaging."

Candidate Name: Michele Moreau
Defense Date: Monday, April 11, 2022
Time: 10 a.m. to noon
Location: Via Zoom

Thesis Title: Investigating the Use of Smart Radiotherapy Biomaterials for Cancer Therapy and Imaging

Advisor: Wilfred Ngwa, Department of Physics and Applied Physics, University of Massachusetts Lowell

Committee Members:

  • Erno Sajo, Department of Physics and Applied Physics, University of Massachusetts Lowell
  • Kwok-Fan Chow, Department of Chemistry, University of Massachusetts Lowell

Abstract: Smart radiotherapy biomaterials (SRBs) have been designed similarly to gold fiducial markers used clinically during image-guided radiotherapy. SRBs are intended to enable programmable in-situ delivery of sufficiently potent concentrations of nanoparticles for controlled release of drug with minimal toxicity. The overall goal of this research is to investigate a novel ‘smart’ multifunctional radiotherapy biomaterial capable of providing image guidance to track tumor motion as well as providing sustained drug release during radiation treatment. The theranostics aspect of the SRB, to provide both imaging and therapy at the tumor site, warrants further optimization of the release of the drug over longer period as well as observing mice survival for extended time. Individuals interested in attending should email Professor Erno Sajo, Director of Medical Physics.

Individuals interested in attending should email Professor Erno Sajo, Director of Medical Physics.