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Anna Yaroslavsky

Anna Yaroslavsky
Anna YaroslavskyAssociate Professor

Research Interests

Development of wide-field high-resolution optical imaging , Light propagation in and interaction with biological tissues, Development of all-optical and multimodal image-guided intervention techniques


  • Ph D: Physics and Mathematics, (1999), Saratov State University - Saratov, Russia
    Dissertation/Thesis Title: Spectroscopic Investigations of Biological Tissues and Fluids
  • BS: Physics, (1990), Saratov State University - Saratov, Russia

Selected Awards and Honors

  • Diploma with Honors (1990)

Selected Publications

  • Yaroslavsky, A., Feng, X., Muzikansky, A., Hamblin, M.R. (2019) "Fluorescence polarization of methylene blue as a quantitative marker of breast cancer at the cellular level", Scientific reports 9:1 pp. 940
  • Malik, S., Jermain, P., Feng, X., Yaroslavsky, A. (2019) "Multimodal optical imaging of renal cells", Optical Engineering 58:8 pp. 082415
  • Feng, X., Muzikansky, A., Ross, A.H., Hamblin, M.R., Jermain, P.R., Yaroslavsky, A. (2019) "Multimodal quantitative imaging of brain cancer in cultured cells", Biomedical Optics Express 10:8 pp. 4237--4248
  • Rohani, P., Yaroslavsky, A., Feng, X., Jermain, P., Shaath, T., Neel, V.A. (2018) "Collagen disruption as a marker for basal cell carcinoma in presurgical margin detection", Lasers in surgery and medicine 50:9 pp. 902--907
  • Cecil, J., Rakesh, P., Alona, M., others, . (2017) "Delineating nonmelanoma skin cancer margins using terahertz and optical imaging", Journal of Biomedical Photonics \& Engineering 3:1
  • Yaroslavsky, A., Feng, X., Neel, V.A. (2017) "Optical mapping of nonmelanoma skin Cancers—A pilot clinical study", Lasers in surgery and medicine 49:9 pp. 803--809
  • Fan, B., Neel, V.A., Yaroslavsky, A. (2016) "Multimodal imaging for nonmelanoma skin cancer margin delineation", Lasers in surgery and medicine
  • Yaroslavsky, A., Joseph, C., Patel, R., Fan, B., Musikansky, A., Neel, V.A., Giles, R.H. (2016) Combined optical and terahertz imaging for intraoperative delineation of nonmelanoma skin cancers pp. S2-10-S2-10
  • Feng, X., Doherty, S., Yaroslavsky, I., Altshuler, G., Yaroslavsky, A. (2015) "Polarization enhanced wide-field imaging for evaluating dermal changes caused by non-ablative fractional laser treatment", Lasers in surgery and medicine
  • Feng, X., Patel, R., Yaroslavsky, A. (2015) "Wavelength optimized cross-polarized wide-field imaging for noninvasive and rapid evaluation of dermal structures", Journal of biophotonics 8:4 pp. 324–331
  • Wirth, D., Snuderl, M., Curry, W., Yaroslavsky, A. (2014) "Comparative evaluation of methylene blue and demeclocycline for enhancing optical contrast of gliomas in optical images", Journal of biomedical optics 19:9 pp. 090504–090504
  • Joseph, C.S., Patel, R., Neel, V.A., Giles, R.H., Yaroslavsky, A. (2014) "Imaging of ex vivo nonmelanoma skin cancers in the optical and terahertz spectral regions Optical and Terahertz skin cancers imaging", Journal of biophotonics 7:5 pp. 295–303
  • Patel, R., Khan, A., Quinlan, R., Yaroslavsky, A. (2014) "Polarization-Sensitive Multimodal Imaging for Detecting Breast Cancer", Cancer research 74:17 pp. 4685–4693
  • Joseph, C.S., Yaroslavsky, A., Neel, V.A., Goyette, T.M., Giles, R.H. (2012) Continuous-wave terahertz reflection imaging of ex vivo nonmelanoma skin cancers pp. 82610X–82610X
  • Michal Kamionek, M., Yaroslavsky, A., Dennis Wirth, B., Quinlan, R.M. (2012) "Feasibility of Dye-Enhanced Fluorescence Confocal Microscopy in Differentiation of Benign and Malignant Breast Tissue", Am J Clin Pathol 138: pp. A367
  • Yaroslavsky, A., Patel, R., Salomatina, E., Li, C., Lin, C., Al-Arashi, M., Neel, V. (2012) "High-contrast mapping of basal cell carcinomas", Optics Letters 37:4 pp. 644-646
  • Wirth, D., Snuderl, M., Sheth, S., Kwon, C., Frosch, M.P., Curry, W., Yaroslavsky, A. (2012) "Identifying brain neoplasms using dye-enhanced multimodal confocal imaging", Journal of Biomedical Optics 17:2 pp. 26012-1
  • Patel, R., Khan, A., Wirth, D., Kamionek, M., Kandil, D., Quinlan, R., Yaroslavsky, A. (2012) "Multimodal optical imaging for detecting breast cancer", Journal of Biomedical Optics 17:6 pp. 66008-1
  • Joseph, C.S., Yaroslavsky, A., Neel, V.A., Goyette, T.M., Giles, R.H. (2011) "Continuous wave terahertz transmission imaging of nonmelanoma skin cancers", Lasers in surgery and medicine 43:6 pp. 457-462
  • Tuchin, V.V., Yaroslavsky, A., Jacques, S.L., Anderson, R. (2010) "Biophotonics for dermatology: science & applications", Journal of biophotonics 3:1-2 pp. 9-10
  • Joseph, C.S., Yaroslavsky, A., Lagraves, J.L., Goyette, T.M., Giles, R.H. (2010) Dual-frequency continuous-wave terahertz transmission imaging of nonmelanoma skin cancers pp. 760104–760104
  • Park, J., Mroz, P., Hamblin, M.R., Yaroslavsky, A. (2010) "Dye-enhanced multimodal confocal microscopy for noninvasive detection of skin cancers in mouse models", Journal of Biomedical Optics 15:2 pp. 26023-26023
  • Yao, M., Yaroslavsky, A., Henry, F.P., Redmond, R.W., Kochevar, I.E. (2010) "Phototoxicity is not associated with photochemical tissue bonding of skin", Lasers in surgery and medicine 42:2 pp. 123-131
  • Tannous, Z., Al-Arashi, M., Shah, S., Yaroslavsky, A. (2009) "Delineating melanoma using multimodal polarized light imaging", Lasers in surgery and medicine 41:1 pp. 10-16
  • Salomatina, E., Muzikansky, A., Neel, V., Yaroslavsky, A. (2009) "Multimodal optical imaging and spectroscopy for the intraoperative mapping of nonmelanoma skin cancer", Journal of Applied Physics 105:10 pp. 102010-102010
  • Yang, M.F., Tuchin, V.V., Yaroslavsky, A. (2009) "Principles of Light-Skin Interactions", Light-Based Therapies for Skin of Color pp. 1-44
  • Joseph, C.S., Yaroslavsky, A., Al-Arashi, M., Goyette, T.M., Dickinson, J.C., Gatesman, A.J., Soper, B.W., Forgione, C.M., Horgan, T.M., Ehasz, E.J., others, . (2009) Terahertz spectroscopy of intrinsic biomarkers for non-melanoma skin cancer pp. 72150I–72150I
  • Demidova-Rice, T., Salomatina, E.V., Yaroslavsky, A., Herman, I.M., Hamblin, M.R. (2007) "Low-level light stimulates excisional wound healing in mice", Lasers in surgery and medicine 39:9 pp. 706-715
  • Al-Arashi, M., Salomatina, E., Yaroslavsky, A. (2007) "Multimodal confocal microscopy for diagnosing nonmelanoma skin cancers", Lasers in surgery and medicine 39:9 pp. 696-705
  • Salomatina, E., Jiang, B., Novak, J., Yaroslavsky, A. (2006) "Optical properties of normal and cancerous human skin in the visible and near-infrared spectral range", Journal of Biomedical Optics 11:6 pp. 64026-64026
  • Anderson, R., Farinelli, W., Laubach, H., Manstein, D., Yaroslavsky, A., Gubeli III, J., Jordan, K., Neil, G.R., Shinn, M., Chandler, W. (2006) "Selective photothermolysis of lipid-rich tissues: A free electron laser study", Lasers in surgery and medicine 38:10 pp. 913-919
  • Demidova, T.N., Herman, I.M., Salomatina, E.V., Yaroslavsky, A., Hamblin, M.R. (2006) "Wound healing stimulation in mice by low-level light", Prog Biomed Opt Imaging 7:26
  • Yaroslavsky, A., Barbosa, J., Neel, V., DiMarzio, C., Anderson, R.R. (2005) "Combining multispectral polarized light imaging and confocal microscopy for localization of nonmelanoma skin cancer", Journal of Biomedical Optics 10:1 pp. 14011-14011
  • Yang, M.U., Yaroslavsky, A., Farinelli, W.A., Flotte, T.J., Rius-Diaz, F., Tsao, S.S., Anderson, R. (2005) "Long-pulsed neodymium: yttrium-aluminum-garnet laser treatment for port-wine stains", Journal of the American Academy of Dermatology 52:3 pp. 480-490
  • Chan, B.P., Amann, C., Yaroslavsky, A., Smink, D., Zarins, B., Kochevar, I.E., Redmond, R.W. (2005) "Photochemical repair of Achilles tendon rupture in a rat model 1", Journal of Surgical Research 124:2 pp. 274-279
  • Schwarzmaier, H., Yaroslavsky, I.V., Yaroslavsky, A., Fiedler, V., Ulrich, F., Kahn, T. (2005) "Treatment planning for MRI-guided laser-induced interstitial thermotherapy of brain tumors The role of blood perfusion", Journal of Magnetic Resonance Imaging 8:1 pp. 121-127
  • Yaroslavsky, A., Neel, V., Anderson, R.R. (2003) "Demarcation of nonmelanoma skin cancer margins in thick excisions using multispectral polarized light imaging", Journal of investigative dermatology 121:2 pp. 259-266
  • Hammer, M., Yaroslavsky, A., Schweitzer, D. (2001) "A scattering phase function for blood with physiological haematocrit", Physics in Medicine and Biology 46:3
  • Yaroslavsky, A., Yaroslavsky, I.V., Goldbach, T., Schwarzmaier, H.J. (1999) "Influence of the scattering phase function approximation on the optical properties of blood determined from the integrating sphere measurements", Journal of Biomedical Optics 4:1 pp. 47-53

Selected Presentations

  • Multiscale and Multimodal Optical Imaging for Delineating Breast Cancers - Breast Cancer Conference, 2012
  • Matching wavelength to applications in polarization sensitive imaging - Photomedicine Lecture, 2012 - Boston, MA
  • Intraoperative functional mapping of eloquent brain cortex for minimizing post-operative neurological deficit - SPIE meeting, 2012 - San Jose, CA
  • Optical color-coding for automated detection of skin cancers - SPIE meeting, 2012 - San Jose, CA
  • Terahertz imaging of nonmelanoma skin cancers - SPIE meeting, 2012 - San Jose, CA
  • Towards In Situ Optical Pathology - Biomedical Optics Workshop, 2010 - Boston, MA
  • Optical Diagnostics: Uncovering Hidden Features of Live Tissue, 2010 - Trondheim, Norway
  • Temperature Induced Changes in the Optical Properties of Skin In Vivo - SPIE meeting, 2010 - San Jose, CA
  • Advanced optical techniques for enhancing specificity of skin cancers detection - International Workshop on Optical technologies in Biophysics and Medicine, 2008 - Saratov, Russia
  • Intraoperative Optical Guidance in Dermatology, 2008
  • Mapping Nonmelanoma Skin Cancers Using Multimodal Macro-Imaging - ISDIS/AAD, 2007 - Washington, DC
  • Optical imaging for Dermatology, 2006 - Skillman, NJ, USA
  • Optical Techniques for Skin Cancer Delineation, 2006 - Barcelona, Spain
  • Towards in situ optical pathology, 2006 - New York City, NY
  • New developments in the optical mapping of nonmelanoma skin cancers - Gordon Research Conference on Lasers in Medicine and Biology, 2004 - Meriden, NH
  • Demarcation of Nonmelanoma Skin Cancers Using Fluorescence and Reflectance Polarization Imaging, 2003 - Saratov, Russia
  • The optical properties of blood in the near infrared spectral range - SPIE meeting, 1996 - San Jose, CA

Selected Intellectual Property

  • Patent - Yaroslavsky, ."Fluorescence polarization imaging device and methods.," Pending
  • Patent - Yaroslavsky, ."Fluorescence polarization imaging device and methods.," 7,289,205 United States
  • Patent - A, Y."Multimodal Imaging for Cancer Detection," United States
  • Patent - A, Y."Devices and Methods for Optical Pathology.," Pending United States
  • Patent - Yaroslavsky, ."Method and apparatus for spectrally resolved imaging of biological tissue.," Pending United States
  • Patent - Yaroslavsky, ."High-contrast high-resolution imaging of skin cancer.," Pending United States
  • Patent - Yaroslavsky, ."Device and method for wide-field and high-resolution imaging.," Pending
  • Patent - Yaroslavsky, ."Polarized light imaging devices and methods.," Pending

Selected Contracts, Fellowships, Grants and Sponsored Research

  • Terahertz and Polarization Optical Imaging (2013), -
    Yaroslavsky, A. (Principal)
  • Towards in Situ Optical Pathology of Nonmelanoma Skin Cancers (2010), Grant -
    Yaroslavsky, A. (Principal)
  • Rental of PERFIS Machine (2011), -
    Yaroslavsky, A. (Principal)
  • Validation of Multimodal Optical Imaging for Detecting Breast Cancer: A Pilot Stu (2010), -
    Yaroslavsky, A. (Principal)