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Lawrence Wolf


Lawrence Wolf
Lawrence M Wolf, Ph.D.Assistant Professor
  • College
    College of Sciences
  • Department
    Chemistry
  • Phone
    (978) 934-5877
  • Office
    Olney Hall - 409
  • Email

Education

  • : Computational/Theoretical Chemistry, (2016), Max-Planck-Institut für Kohlenforschung - Mülheim an der Ruhr, Germany
  • Ph D: Organic Chemistry, (2012), University of Illinois - Urbana-Champaign, IL
    Dissertation/Thesis Title: Catalyst Development in Asymmetric Phase Transfer Catalysis Employing QSAR Methods & Computational Investigations on the Stereochemical Course of the Addition of Allylsilanes to Aldehydes
  • BS: Chemistry, (2006), Drexel University - Philadelphia, PA
    Supporting Area: Physics

Selected Publications

  • Wang, F. (Changchun Institute of Applied Chemistry), Li, J. (Changchun Institute of Applied Chemistry), Wolf, L.M. (University of Massachusetts Lowell), Liu, K. (Changchun Institute of Applied Chemistry), Zhang, H. (Changchun Institute of Applied Chemistry) (2019). A bifunctional electrode engineered by sulfur vacancies for efficient electrocatalysis. Nanoscale, 11(35) 16658-16666.
  • Wolf, L.M., Thiel, W. (Max-Planck-Institute Fuer Kohlenforschung) (2019). Computational Investigations into the Mechanisms of Trans-Selective Hydrogenation and Hydrometalation of Alkynes (1317: pp. 57-69). ACS Symposium Series
  • Rajasekhar, T., Emert, J., Wolf, L.M., Faust, R. (2018). Controlled Catalytic Chain Transfer Polymerization of Isobutylene in the Presence of tert-Butanol as Exo-Enhancer. Macromolecules, 51 3041-3049.
  • Guthertz, A., Leutzsch, M., Wolf, L.M., Gupta, P., Rummelt, S.M., Goddard, R., Farès, C., Thiel, W., Fürstner, A. (2018). Half-Sandwich Ruthenium Carbene Complexes Link trans-Hydrogenation and gem-Hydrogenation of Internal Alkynes. Journal of the American Chemical Society, 140 3156-3169.
  • Lee, Y., Wang, M., Kokubo, K., Kang, N., Wolf, L.M., Tan, L., Chen, C., Chiang, L. (2018). New 2d-Stereoconfigured Cis-Tris(Fluorenylphenylamino)-Benzene with Large Steric Hindrance to Minimize Stacking in Thin-Film Devices. Dyes and Pigments, 149 377-386.
  • Huang, L., Wang, M., Huang, Y., El-Hussein, A., Wolf, L.M., Chiang, L.Y., Hamblin, M.R. (2018). Progressive Cationic Functionalization of Chlorin Derivatives for Antimicrobial Photodynamic Inactivation and Related Vancomycin Conjugates . Photochemical and Photobiological Sciences, 17 638-651.
  • Gu, L., Wolf, L.M., Thiel, W., Lehmann, C.W., Alcarazo, M. (2018). Reductive Elimination of C 6 F 5 − C 6 F 5 from Pd(Ii) Complexes: Influence of α ‑Dicationic Chelating Phosphines. Organometallics, 37 665-672.
  • Roşca, D., Radkowski, K., Wolf, L.M., Wagh, M., Goddard, R., Thiel, W., Fürstner, A. (2017). Ruthenium-Catalyzed Alkyne trans-Hydrometalation: Mechanistic Insights and Preparative Implications. Journal of the American Chemical Society, 139 2443-2455.
  • Gu, L., Wolf, L.M., Zieliński, A., Thiel, W., Alcarazo, M. (2017). α-Dicationic Chelating Phosphines: Synthesis and Application to the Hydroarylation of Dienes. Journal of the American Chemical Society, 139 4948-4953.
  • Boess, E., Wolf, L.M., Malakar, S., Salamone, M., Bietti, M., Thiel, W., Klussmann, M. (2016). Competitive Hydrogen Atom Transfer to Oxyl- and Peroxyl Radicals in the Cu-Catalyzed Oxidative Coupling of N-Aryl Tetrahydroisoquinolines Using tert-Butyl Hydroperoxide. ACS Catalysis, 6 3253-3261.
  • Ilg, M.K., Wolf, L.M., Mantilli, L., Farès, C., Thiel, W., Fürstner, A. (2015). A Striking Case of Enantioinversion in Gold Catalysis and Its Probable Origins. Chemistry—A European Journal, 21 12279-12284.
  • Xie, L., Bagutski, V., Audisio, D., Wolf, L.M., Schmidts, V., Hofmann, K., Wirtz, C., Thiel, W., Thiele, C.M., Maulide, N. (2015). Dynamic Behavior of Monohaptoallylpalladium Species: Internal Coordination as a Driving Force in Allylic Alklylation Chemistry. Chemical Science, 6 5734-5739.
  • Leutzsche, M., Wolf, L.M., Gupta, P., Fuchs, M., Thiel, W., Farès, C., Fürstner, A. (2015). Formation of Ruthenium Carbenes by Gem-Hydrogen Transfer to Internal Alkynes: Implications for Alkyne trans-Hydrogenation. Angewandte Chemie International Edition, 54 12431-12436.
  • Wolf, L.M., Thiel, W. (2014). Origin of Inversion versus Retention in the Oxidative Addition of 3-Chloro-cyclopentene to Pd(0)Ln. Journal of Organic Chemistry, 79 12136-12147.
  • Wolf, L.M., Denmark, S.E. (2013). A Theoretical Investigation on the Mechanism and Stereochemical Course of the Addition of (E)-2-Butenyltrimethylsilane to Acetaldehyde by Electrophilic and Nucleophilic Activation. Journal of the American Chemical Society, 135 4743-4756.
  • Denmark, S.E., Weber, E.J., Almstead, N.J., Wolf, L.M. (2012). On the Stereochemical Course of the Addition of Allylsilanes to Aldehydes. Tetrahedron, 68 7701-7718.
  • Denmark, S.E., Gould, N.D., Wolf, L.M. (2011). A Systematic Investigation of Quaternary Ammonium Ions as Asymmetric Phase Transfer Catalysts. Application of Quantitative Structure Activity/Selectivity Relationships. Journal of Organic Chemistry, 76 4337-4357.

Selected Presentations

  • Understanding the endo/exo Selectivity Enhancement in the Diels-Alder Reaction under Lewis Acid Activation and post-TS Bifurcation in the Oxidative Addition to LnPd - Symposium on Electronic Structure and Dynamics of Complex Systems, April 2019 - Beijing, China
  • Mechanistic Investigations in Alkyne Hydrogentation, Allylation, and Phase Transfer Catalysis guided by DFT, 2016 - Changchun, China
  • A DFT Study on the Ru Catalyzed trans-Hydrogenation of Alkynes: Unique Access to a Ru-carbene - The 13th International Kyoto Conference on New Aspects of Organic Chemistry, November 2015 - Kyoto, Japan
  • A DFT Study on the Ru Catalyzed trans-Hydrogenation of Alkynes - Biannual Max-Planck-Institut Internal Seminar, April 2015 - Mülheim, an der Ruhr, Germany
  • Origin of Inversion vs Retention in the Oxidative Addition of 3-chlorocyclopentene to Pd(0)Ln - 50th Symposium on Theoretical Chemistry, September 2014 - Vienna, Austria
  • On the Selectivity of Inversion vs Retention in The Oxidative Addition of Allylic Halides by Palladium - Binnual Max-Planck-Institut Internal Seminar, December 2013 - Mülheim, an der Ruhr, Germany
  • Investigation of Phase Transfer Catalysis Employing Quantitative Structure Activity Relationships - Fuson Travel Award Lecture, August 2011 - Urbana-Champaign, IL
  • Investigation of Phase Transfer Catalysis Employing Quantitative Structure Activity Relationships - Physical Organic Gordon Research Conference, June 2011 - Holderness, NH
  • The Application of QSAR/QSSR Methods for Catalyst Evaluation and Development in Phase Transfer Catalysis - 23rd Annual Allerton Research Conference, November 2009 - Urbana-Champaign, IL

Research Currently in Progress

  • Our current research interests include the development and application of modern reactivity models for elucidating reactivity/selectivity principles focused in transition metal mediated catalysis, organocatalysis, as well as applying strategies in computer aided catalyst design.
    Wolf, L.