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Juan Artes Vivancos


image of Juan Artes Vivancos
Juan Manuel Artes Vivancos, Ph.D.Assistant Professor

Research Interests

Biochemistry and Biophysics:<br><br>Protein, DNA, and RNA biophysics at the single molecule level. Development of biosensors

<a href="http://faculty.uml.edu/artes/">http://faculty.uml.edu/artes/</a><br><br>The complete biochemical understanding of several processes in Biology requires bridging the gaps between studies at the different levels; organisms, tissues, cells, membranes, and single molecules. To this end, studies of biophysics at the individual molecule level are demanding new integrated approaches leading to a complete picture containing all the different perspectives: spatial resolution at the nanoscale, energetics of the processes, and (ultrafast) dynamics taking place.<br><br>The field of single-molecule biophysics has experienced a boom in the last decades. Not only developments in optical microscopy and spectroscopy have allowed circumventing the diffraction limit and studying biological details with high resolution, but nanoscience tools such as Scanning Probe Microscopies (SPM) have paved the way for biophysical studies at the single-molecule level. I aim to integrate approaches in SPM, bioelectronics, and spectroscopy with the last advances in nanoscience to establish a two-way translational research platform.<br><br>The Biosystems I study include:<br>Proteins and protein complexes, including antibodies.<br>Nucleic acids, including DNA and RNA.<br><br>Besides studying biophysics at the single-molecule level, I use these results for the development of sensors for a variety of applications.

Biography

Juan Artes obtained his Ph.D. from the University of Barcelona researching single-molecule bioelectronics and electrochemistry. He did a postdoc at the University of California Davis, developing new methods for the electrical detection of oligonucleotides using nanoscience tools. In a second postdoctoral experience funded by the European Comission (Marie Curie Individual Fellowship) at the VU Amsterdam, he explored new spectroscopy methods for the study of ultrafast biophysical phenomena, such as photosynthesis.

Selected Publications

  • Li, Y., Artes Vivancos, J., Demir, B., Gokce, S., Mohammad, H.M., Alangari, M., Anantram, M., Oren, E.E., Hihath, J. (2018). Detection and identification of genetic material via single-molecule conductance. Nature nanotechnology, 13(12) 1167.
  • Lopez-Martinez, Montserrat, ., Artes Vivancos, J., Sarasso, V., Carminati, M., Diez-Perez, Ismael, ., Sanz, F., Gorostiza, P. (2017). Differential electrochemical conductance imaging at the nanoscale. Small, 13(36) 1700958.
  • Artes Vivancos, J., Hihath, J., Diez-Perez, I. (2016). Biomolecular electronics. Molecular Electronics, 281--313.
  • Li, Y., Artes Vivancos, J., Qi, J., Morelan, I.A., Feldstein, P., Anantram, M.P., Hihath, J. (2016). Comparing Charge Transport in Oligonucleotides: RNA: DNA Hybrids and DNA Duplexes. The journal of physical chemistry letters, 7(10) 1888--1894.
  • Li, Y., Artes Vivancos, J., Hihath, J. (2016). Long-Range Charge Transport in Adenine-Stacked RNA: DNA Hybrids. Small, 12(4) 432--437.
  • Rascon-Ramos, Habid, ., Artes Vivancos, J., Li, Y., Hihath, J. (2015). Binding configurations and intramolecular strain in single-molecule devices. Nature materials, 14(5) 517.
  • Artes Vivancos, J., Hihath, J., Diez-Perez, I. (2015). Biomolecular Electronics (pp. 281--323). Pan Stanford
  • Artes Vivancos, J., Li, Y., Qi, J., Anantram, M., Hihath, J. (2015). Conformational gating of DNA conductance. Nature communications, 6 8870.
  • Giannotti, M.I., Cabeza de Vaca, I., Artes Vivancos, J., Sanz, F., Guallar, V., Gorostiza, P. (2015). Direct Measurement of the Nanomechanical Stability of a Redox Protein Active Site and Its Dependence upon Metal Binding. The Journal of Physical Chemistry B, 119(36) 12050--12058.
  • Artes Vivancos, J., Lopez-Martinez, M., Diez-Perez, I., Sanz, F., Gorostiza, P. (2014). Conductance Switching in Single Wired Redox Proteins. Small, 10(13) 2537--2541.
  • Lagunas, A., Castano, A.G., Artes Vivancos, J., Vida, Y., Collado, D., Perez-Inestrosa, E., Gorostiza, P., Claros, S., Andrades, J.A., Samitier, J. (2014). Large-scale dendrimer-based uneven nanopatterns for the study of local arginine-glycine-aspartic acid (RGD) density effects on cell adhesion. Nano Research, 7(3) 399--409.
  • Artes Vivancos, J., Lopez-Martinez, M., Diez-Perez, I., Sanz, F., Gorostiza, P. (2014). Nanoscale charge transfer in redox proteins and DNA: Towards biomolecular electronics. Electrochimica Acta, 140 83--95.
  • Guo, S., Artes Vivancos, J., Diez-Perez, I. (2013). Electrochemically-gated single-molecule electrical devices. Electrochimica Acta, 110 741--753.
  • Artes Vivancos, J., Lopez-Martinez, M., Giraudet, A., Diez-Perez, I., Sanz, F., Gorostiza, P. (2012). Current--Voltage Characteristics and Transition Voltage Spectroscopy of Individual Redox Proteins. Journal of the American Chemical Society, 134(50) 20218--20221.
  • Simao, C., Mas-Torrent, M., Crivillers, N., Lloveras, V., Artes Vivancos, J., Gorostiza, P., Veciana, J., Rovira, C. (2011). A robust molecular platform for non-volatile memory devices with optical and magnetic responses. Nature Chemistry, 3(5) 359.
  • Artes Vivancos, J., Diez-Perez, Ismael, ., Sanz, F., Gorostiza, P. (2011). Direct Measurement of Electron Transfer Distance Decay Constants of Single Redox Proteins by Electrochemical Tunneling Spectroscopy. ACS nano, 5(3) 2060--2066.
  • Artes Vivancos, J., Diez-Perez, I., Gorostiza, P. (2011). Transistor-like Behavior of Single Metalloprotein Junctions. Nano letters, 12(6) 2679--2684.
  • Caballero-Briones, F., Artes Vivancos, J., Diez-Perez, I., Gorostiza, P., Sanz, F. (2008). Direct observation of the valence band edge by in situ ECSTM-ECTS in p-type Cu2O layers prepared by copper anodization. The Journal of Physical Chemistry C, 113(3) 1028--1036.

Selected Contracts, Fellowships, Grants and Sponsored Research

  • EAGER: Electrical detection of biomolecular interactions and machine learning-assisted simulations: from single-molecule biophysics to biological complexes (2020), Grant - NSF
    Artes Vivancos, J.M.
  • 2019-2020 Wong Research Fund Award (2020), Sponsored Research -
    Artes Vivancos, J.