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Matthew Gage

Gage-Matthew
Matthew GageAssociate Professor, Principal Investigator

Education

  • Ph D: Biochemistry and Molecular Biology, (2001), Purdue University - Indiana,USA
    Dissertation/Thesis Title: Interaction of the Virally Encoded Fungal Toxin KP4 with Calcium Channels (Advisor : Prof. Thomas J. Smith).
  • BS: Chemistry, (1996), University of Wyoming - Wyoming, USA
  • BS: Molecular Biology with Honors, (1996), University of Wyoming - Wyoming, USA

Awards and Honors

  • Dean's List - University of Wyoming
  • NIH Biophysics Training Grant (2001) - Purdue University
  • Honor Book, Department of Molecular Biology. (1996) - University of Wyoming
  • Outstanding Student, Department of Chemistry (1996) - University of Wyoming
  • NSF REU Fellow, Department of Chemistry (1995) - University of Wyoming

Publications

  • Tiffany, H., Sonkar, K., Gage, M. (2017) "The insertion sequence of the N2A region of titin exists in an extended structure with helical characteristics.," BBA - Proteins & Proteomics!!! 1865:1 pp. 1 - 10
  • Athar, H., Gage, M. (2016) "Assessing the Functional Role of Titin N2A-PEVK Region in Active Muscle Contraction.," Biophysical Journal 3
  • Done, A.J., Gage, M., Nieto, N.C., Traustad√≥ttir, T. (2016) "Exercise-induced Nrf2-signaling is impaired in aging.," Free Radical Biology & Medicine!!! 96: pp. 130 - 138
  • Premawardhana, S., Gage, M. (2016) "The PEVK Region of Titin: Deciphering the Molecular Interactions of Elasticity.," Biophysical Journal 3

Presentations

  • Characterization of the intrinsically Disordered Region of Soluble Guanylate Cyclase Aplha-1 Subunit" poster, Candice V. Benally, Parul Singh, and Matthew Gage, February 2014, Biophysical Society Annual Meeting. - Poster and Seminar Presentations, February 2014 - San Francisco, CA
  • Structural Studies on the N2A-IS Region of Titin poster, Kanchan Sonkar, Holly Tiffany, and Matthew Gage, February 2014, Biophysical Society Annual meeting, San Francisco, CA." - Poster and Seminar Presentations, February 2014
  • Intrinsically Disordered Proteins: Understanding protein Function in the Absence of Structure - Seminar Presentations, February 2013 - Fargo, ND
  • Exploring the World of Intrinsically Disordered proteins" Matthew Gage, January 2013, IMSD Regional Meeting". - Invited Talk, January 2013 - Arizona
  • Developing Inhibitors for E. Coli tryptophan Synthase and Indole -3- Glyserol Phosphate Synthase Utilizing in vitro and in silico techniques - Poster, August 2012 - San Diego, CA
  • Characterizing the Structure and Function of Truncations from the Anti-Sigma Factor FlgM from Aquifex aeolicus - Poster and Talk, August 2012 - San Diego, CA
  • - Structural Characterization of the Unique Sequence Region from the N2A Domain of Titin, August 2012 - San Diego, CA
  • Thrombospondin-1 binding to CD 47 in the Regulation of Nitric Oxide Signaling, , August 2012 - San Diego, CA
  • Determining the Effects of various Crowding Agents on eGEP to Model Folding within the Cell, Poster, Amber Enriquez and Matthew Gage . - Poster, July 2011 - Boston, MA
  • Developing Inhibitors for Tryptophan Synthase Utilizing in Vitro and in Silico Studies was done by Holly Tiffany and Matthew Gage . - Poster, July 2011 - San Diego, CA
  • Development of Novel inhibitors of Indole glycerol -3-Phosphate, was done by Andrew Allen, Dorothy Kampf and Matthew Gage. - Poster, July 2011 - Boston, MA
  • Assessing the Degree of Disorder in Homologous FlgM proteins, Poster and Talk was done by Rachel Brackett, Wai kit ma and Matthew Gage. - Poster and Talk, July 2011 - Boston, MA
  • Assessing Various Ways to Mimic the Cellular Environment , was successfully done by Avery Fricker, Chad park and Matthew Gage. - Poster and Talk, July 2011 - Boston ,MA
  • Aquifex aeolicus FlgM protein exhibits a temperature dependent disordered nature - poster, July 2010 - San Diego, CA
  • Designing novel antimicrobial compounds to inhibit unexplored metabolic pathways,'' Poster, Andrew Allen, Samuel Gilmore, Rhett Molloy, Allison Grace, Jason McCabe, Cindy Browder, Matthew Gage", was done in July 2010. - Poster, July 2010 - San Diego, CA
  • Exploring conformational changes associated with binding of YC-1 to soluble guanylyl cyclase, Poster, Malia Davis, Camille Aguilera, Shauna Cooney, Matthew Gage, July 2010. - Poster, July 2010 - San Diego, CA
  • Development of Inhibitors of the Methionine and Tryptophan Biosynthetic pathways, Seminar was done by Matthew J. Gage, DTRA TMT Quarterly Meeting in July 2010. - Seminar, July 2010
  • Aquifex aeolicus FLgM Protein exhibits a temperature dependent disordered nature., February 2010 - San Francisco, CA.
  • Applying Thermodynamics to Fragment -based Drug Development - Seminar and Poster publications, February 2010 - San Francisco, CA
  • Assessing the degree of disorder in homologous FlgM proteins. - Seminar Presentations, February 2010 - San Francisco, CA.