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Susanna Remold


Susanna Remold
Susanna RemoldDepartment Chair, Professor

Research Interests

A main focus of my work is to understand the connections between fundamental ideas from ecological and evolutionary theory and solutions to human health and welfare problems. I address this in my research and how I work with students. My group works on the ecology and evolution of microbes, in particular ones associated with human disease. Currently our lab focuses on bacteria in the genus <i>Pseudomonas</i> from human homes and from the people and pets living in them. We combine studies of the distributions of these organism, studies of their patterns of phenotypic variability, and investigations of the genomic underpinnings of these phenotypes, and the evolutionary pressures that help mold them.

Education

  • BS: Biology, University of Michigan
  • Ph D: Ecology and Evolutionary Biology, Cornell University

Selected Publications

  • Bara, J., Matson, Z., Remold, S. (). Life in the cystic fibrosis upper respiratory tract influences competitive ability of the opportunistic pathog en Pseudomonas aeruginosa.
  • V\"astermark, Jeremy V, ., Bruder, C., Remold, S., Chu, Y., Mardhanan, P., McAllister, R., Jonsson, C.B. (). The Murine Model for Hantaan virus-Induced Lethal Disease Shows Two Distinct Paths in Viral Evolutionary Trajectory with or without Ribavirin Treatment. Dong-Hoon Chung1, 2, \AAke.
  • Diaz, K.E., Remold, S., Onyiri, O., Bozeman, M., Raymond, P.A., Turner, P.E. (2018). Generalized Growth of Estuarine, Household and clinical isolates of Pseudomonas aeruginosa. Frontiers in microbiology, 9 305.
  • Bara, J.J., Matson, Z., Remold, S. (2018). Life in the cystic fibrosis upper respiratory tract influences competitive ability of the opportunistic pathogen Pseudomonas aeruginosa. Royal Society open science, 5(9) 180623.
  • Morley, V.J., Sistrom, M., Usme-Ciro, J.A., Remold, S., Turner, P.E. (2016). Evolution in spatially mixed host environments increases divergence for evolved fitness and intrapopulation genetic diversity in RNA viruses. Virus evolution, 2(1).
  • France, M.T., Remold, S. (2016). Interference competition among household strains of Pseudomonas. Microbial ecology, 72(4) 821--830.
  • Purdy-Gibson, M., France, M., Hundley, T., Eid, N., Remold, S. (2015). Pseudomonas aeruginosa in CF and non-CF homes is found predominantly in drains. Journal of Cystic Fibrosis, 14(3) 341--346.
  • Remold, S., Purdy-Gibson, M.E., France, M.T., Hundley, T.C. (2015). Pseudomonas putida and Pseudomonas fluorescens species group recovery from human homes varies seasonally and by environment. PloS one, 10(5).
  • Bara, J., Clark, T., Remold, S. (2014). Utilization of larval and pupal detritus by Aedes aegypti and Aedes albopictus. Journal of Vector Ecology, 39(1) 44--47.
  • McGee, L.W., Remold, S. (2013). Pleiotropic interactions involving virulence and replication rate in experimentally evolved vesicular stomatitis virus. Evolutionary Ecology Research, 15(5) 567--578.
  • Bara, J., Clark, T., Remold, S. (2013). Susceptibility of larval Aedes aegypti and Aedes albopictus (Diptera: Culicidae) to dengue virus. Journal of medical entomology, 50(1) 179--184.
  • Chung, D., V\"astermark, \AAke, ., Camp, J.V., McAllister, R., Remold, S., Chu, Y., Bruder, C., Jonsson, C.B. (2013). The murine model for Hantaan virus-induced lethal disease shows two distinct paths in viral evolutionary trajectory with and without ribavirin treatment. Journal of virology, 87(20) 10997--11007.
  • Remold, S. (2012). Understanding specialism when the jack of all trades can be the master of all. Proceedings of the Royal Society B: Biological Sciences, 279(1749) 4861--4869.
  • Remold, S., Brown, C.K., Farris, J.E., Hundley, T.C., Perpich, J.A., Purdy, M.E. (2011). Differential habitat use and niche partitioning by Pseudomonas species in human homes. Microbial ecology, 62(3) 505.
  • Purdy, M., France, M., Hundley, T., Eid, N., Remold, S. (2011). IDENTIFICATION OF SITES HARBORINGPSEUDOMONAS AERUGINOSAIN CF AND NON-CF HOMES: 315. Pediatric Pulmonology, 46(34).
  • O’Keefe, K.J., Silander, O.K., McCreery, H., Weinreich, D.M., Wright, K.M., Chao, L., Edwards, S.V., Remold, S., Turner, P.E. (2010). Geographic differences in sexual reassortment in RNA phage. Evolution: International Journal of Organic Evolution, 64(10) 3010--3023.
  • Turner, P.E., Morales, N.M., Alto, B.W., Remold, S. (2010). Role of evolved host breadth in the initial emergence of an RNA virus. Evolution: International Journal of Organic Evolution, 64(11) 3273--3286.
  • Gibson, L.R., Li, B., Remold, S. (2010). Treating cofactors can reverse the expansion of a primary disease epidemic. BMC infectious diseases, 10(1) 248.
  • Lutskiy, M.I., Park, J.Y., Remold, S., Remold-O'Donnell, E. (2008). Evolution of highly polymorphic T cell populations in siblings with the Wiskott-Aldrich Syndrome. PLoS One, 3(10).
  • Remold, S., Rambaut, A., Turner, P.E. (2008). Evolutionary genomics of host adaptation in vesicular stomatitis virus. Molecular biology and evolution, 25(6) 1138--1147.
  • Cooper, T.F., Remold, S., Lenski, R.E., Schneider, D. (2008). Expression profiles reveal parallel evolution of epistatic interactions involving the CRP regulon in Escherichia coli. PLoS genetics, 4(2).
  • Froissart, R., Wilke, C., Montville, R., Remold, S., Chao, L., Turner, P. (2006). CORRIGENDUM-Co-infection weakens selection against epistatic mutations in RNA viruses. Genetics, 172(4) 2705--2706.
  • Froissart, R., Wilke, C.O., Montville, R., Remold, S., Chao, L., Turner, P. (2006). Erratum: Co-infection weakens selection against epistatic mutations in RNA viruses,(Genetics 168,(9-19)). Genetics, 172(4).
  • Remold, S. (2006). Protein expression tells only half the story. Nature genetics, 38(9) 979--980.
  • Montville, R., Froissart, R., Remold, S., Tenaillon, O., Turner, P.E. (2005). Evolution of mutational robustness in an RNA virus. PLoS biology, 3(11).
  • Froissart, R\'emy, ., Wilke, C.O., Montville, R., Remold, S., Chao, L., Turner, P.E. (2004). Co-infection weakens selection against epistatic mutations in RNA viruses. Genetics, 168(1) 9--19.
  • Clark, T.M., Flis, B.J., Remold, S. (2004). Differences in the effects of salinity on larval growth and developmental programs of a freshwater and a euryhaline mosquito species (Insecta: Diptera, Culicidae). Journal of Experimental Biology, 207(13) 2289--2295.
  • Remold, S., Lenski, R.E. (2004). Pervasive joint influence of epistasis and plasticity on mutational effects in Escherichia coli. Nature genetics, 36(4) 423--426.
  • Clark, T.M., Flis, B.J., Remold, S. (2004). pH tolerances and regulatory abilities of freshwater and euryhaline Aedine mosquito larvae. Journal of Experimental Biology, 207(13) 2297--2304.
  • Remold, S. (2002). Unapparent virus infection and host fitness in three weedy grass species. Journal of Ecology, 967--977.
  • Remold, S., Lenski, R.E. (2001). Contribution of individual random mutations to genotype-by-environment interactions in Escherichia coli. Proceedings of the National Academy of Sciences, 98(20) 11388--11393.
  • Remold, S. (1999). Evolutionary ecology of host use in the barley yellow dwarf virus disease system.
  • Power, A.G., Remold, S. (1996). Incidence of barley yellow dwarf virus in wild grass populations: implications for biotechnology risk assessment (pp. 58--65).