BioManufacturing Center

Case Studies

E. COLI Fermentation Development

E. coli is the organism of choice for nonglycosylated recombinant protein production. Proteins can be expressed as inclusion bodies, intracellular soluble protein or periplasmic secreted proteins. E. coli has many advantages for use as a production host.

View the complete E. Coli Fermentation Development case study (pdf)

Analytical Development and Characterization

A variety of state-of-the-art tools are used to characterize the recombinant protein GPIB-FC in order to understand the basis of aggregate formation.

The Role of Disulfide Bond Formation (pdf)