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Cores

Core Expertise

For fee-for-service inquiries, please Contact Us.

Dietary Assessment

The dietary assessment core, led by Katherine Tucker, is a fully equipped research facility available to members and fee-for-service contracts.

This core offers expertise in:

  • Study and instrument design for collection of dietary data
  • Collection and processing of dietary records, 24-hour dietary recalls and food frequency questionnaires (FFQ)
  • Linking dietary and nutrition data to health outcomes, including NHANES
  • Interviewer training
  • Statistical analysis to describe the food and nutrient intake of groups, including dietary patterning (e.g. indices)
  • Validation of dietary assessment tools

In addition to processing standard questionnaires, we have developed specialized food frequency questionnaires (FFQ) for use with Hispanic adults in the Northeastern US and in Puerto Rico (Puerto Ricans, Dominicans and Central Americans); and another for use in the Southern US (Mississippi Delta region), which has been modified for use in the NHLBI Jackson Heart Study.

Our staff includes programmers experienced in writing SAS programs to link scanned output to dietary database contents and to create output reports for foods and nutrients from food frequency questionnaires. They are also conversant in creating food groups and other food and nutrient variables for use in analysis.

Lab

Under the direction of Mahdi Garelnabi, the laboratory core provides analysis of nutrients, biomarkers and clinical Laboratory measurements for members and fee-for-service contracts.

Garelnabi’ s laboratory, located at the newly built UMass Lowell's Emerging Technologies and Innovation Center (ETIC) - an $80-million-dollar facility - covers 84,000 square feet with state-of-art instruments. His research lab focuses on the molecular and biochemical modulators of metabolic diseases such as cardiovascular, diabetes and obesity.

Laboratory Core Capabilities
Cell Culture Room Nuaire Biological Safety Cabinets (class II, Type 2A) VWR CO2 incubators
Olympus BH-2, CK2 piXellnk camera empowered microscopes Qubit® Nucleic Acids Quantification Platform
Centrifuges with and without cooling systems, water baths, hotplate/stir plates, and vortexes GE EPS Electrophoresis system
Thermo Scientific pH meter Tuttnauer autoclave
Hitachi F2500 Fluorescence spectrophotometer Shimadzu UN mini 1240 spectrophotometer
Eppendorf Mastercycle gradient Thermocycler Infinite® M1000 - top class microplate reader with premium Quad4 Monochromators™ microplate reader
Applied BioSystems Triple Quad™ LC/MS/MS System Beckman ultracentrifuge L8 70W
Avanti® JE ultracentrifuge V max Molecular Devices kinetic microplate reader
Fisher Scientific pH Meters Varian Inc 430 GC, FID with CP 8410 auto sampler
BioRad MyiQ2 Real Time PCR instrument Bio Spectrum Gel Capture System
BioRad Bio PAC 300 Electrophoresis system for PCR Gas Chromatograph / Mass Spectrometer: Shimadzu GCMS-QP2010 Plus
Autosampler: Shimadzu AOC-5000 Auto Injector Gas Chromatograph / Electron Capture Detector: HP 6890 GC System
GC Autosmapler: Agilent 7683L8-70 Beckman ultracentrifuge and rotor (40.3 and 5W-41) Avanti J-E Beckman high speed centrifuge
Roche Cobas Mira Clinical Chemistry Auto-Analyzer Molecular Devices Kinetic Instrument microplate reader
Olympics light microscope with computerized image analysis system UV-VIS spectrophotometers
Agarose, polyacrylamide, and isoelectric focusing gel electrophoresis units Flourometer
Platelet aggragometer Western Blot unit
PCR instrument Pipettes covering a range of 0.1 to 1000 μL
-20°C freezer -80 °C freezer
Microwave oven Refrigerator

More details can be found on the UMass Lowell Core Research Facilities website.

Biostatistics

The biostatistics core is a shared resource for Center members led by John Griffith, providing consultation on biostatistics, with special expertise in dietary data analysis. Additionally, the core supports design and analysis of research studies.

This core offers:
Consultation on protocol design Participation on manuscript preparation
Collaboration on grant proposals Analyses for abstracts
Fee-for-service consultation contracts Study monitoring

Administrative

The administrative core, led by Esther Carver, MPH, provides an efficient, centralized unit for fiscal and administrative operations. Center members have access to this core, providing support with grant submissions, IRB applications, data management and more.

Resources