The Laboratory for Neuroscience Research seeks to understand the basic mechanisms that maintain nervous system health, how errors in these processes lead to the progressive loss of nervous system function in normal aging, Alzheimer's disease and Amyotropic Lateral Sclerosis, and to develop and implement novel computer-nervous system interfaces. 

The Laboratory was established at Harvard Medical School in the late 1980's and relocated to UMass Lowell in 1994.