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Margaret J. Koziel

Dr. Koziel is the Senior Director for Clinical Research in the University of Massachusetts center for clinical and translational sciences, Assistant Vice Provost for Clinical Research and a professor of medicine at the University of Massachusetts Medical School.
Margaret J. Koziel, M.D. M2D2 Director; Senior Director of Clinical Research - UMass Center for Clinical & Translational Science, University of Massachusetts Medical School, Worcester

Educational Background

BA and MD - Dartmouth College
Postgraduate Medical Training - New England Deaconess Hospital and Massachusetts General Hospital

Biosketch

Dr. Koziel is the Senior Director for Clinical Research in the University of Massachusetts center for clinical and translational sciences, Assistant Vice Provost for Clinical Research and a professor of medicine at the University of Massachusetts Medical School. The UMass Center for Clinical and Translational Sciences is a 5 campus effort, the goals of which are:

  1. to accelerate the translation of basic discoveries into practical, cost effective solutions that improve human health; and
  2. to develop and support the next generation of leaders in clinical and translational research.

By supporting investigation that improves the science of translation and that accelerates the translation of UMass discoveries into products for clinical use, we will improve the health of our community and the world. Dr. Koziel’s specific responsibilities include oversight of the clinical research infrastructure to support the full spectrum of clinical research that occurs at UMass, and the support services for clinical trials. She is also a director of the Massachusetts Medical Device Development Center (M2D2), a collaborative program of UMass Worcester and UMass Lowell to offer inventors and entrepreneurs space and services to further product development, particularly in medical devices.

Dr. Koziel was previously on the medical staff at the Beth Israel Deaconess medical center and an associate professor of medicine at Harvard Medical School, where her research interest was the immune response to hepatitis C virus, as well as advancing the clinical care of people with HIV. While at the Beth Israel Deaconess, she received numerous awards for her research, including being named as a Fellow of the Infectious Disease Society of America and a member of the American Society of Clinical Investigation. She then moved to the Novartis Institute for Biomedical Research, where she was the head of translational medicine in infectious diseases; followed by Vertex Pharmaceuticals where she led late stage development in hepatitis C therapeutics. As part of her responsibilities in industry, she was responsible for leading teams of individuals in all phases of drug development, as well as due diligence and other business development activities. She particularly enjoys linking the process of discovery with addressing unmet medical needs, and will assist the IBD team and our investigators on the path to IND and marketing approval, particularly around planning for clinical studies and the development of preclinical packages to support clinical development.

Dr. Koziel has published nearly 80 papers, including in journals such as the New England Journal of Medicine and The Journal of Clinical Investigation. Her personal research interests remain in addressing unmet medical needs, particularly in the field of infectious disease. She is also an attending physician at the UMass Memorial Medical center.

She obtained her BA and MD from Dartmouth College, and her postgraduate medical training at the New England Deaconess Hospital and Massachusetts General Hospital.