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Provides exposure to cutting-edge biomedical technologies in a number of different areas with a balance between biomedical engineering and biotechnology areas.
Pre-req: HSCI 2510 Physiological Chemistry I, or CHEM 1210 Chemistry I, or CHEM 1110 General Chemistry I, and PHYS 1030 General Physics I, and PHYS 1030L General Physics Lab I, or PHYS 1410 Physics I, or PHYS 1410L Physics I Lab.
This course provides undergraduate students in Biomedical Engineering the opportunity to expand their knowledge of Biomedical Engineering career opportunities and develop required skills. Content includes the development of professional skills (career opportunities, resume writing, etc) and an exploration of current research areas through presentations by faculty (and/or off-campus subject matter experts) and through literature review.
Introduces programming logic for engineers. Covers fundamentals of procedural programming with applications in Biomedical Engineering and embedded systems. Topics include variables, expressions and statements, console input/output, modularization and functions, arrays, pointers and strings algorithms, structures, and file input/output. Introduces working with Matlab. Laboratories include designing and programming engineering applications.
BME Majors Only or Permission of Instructor.
This course introduces fundamental of instrumentation for biological applications. In this course we will explore sources of signals, detection of these signals, signals to noise, and data processing. We will learn how to analyze circuits including energy storage elements, op-amps, and filters.
Pre-req: MATH.1320 Calculus II, and PHYS.1440 Physics II, and BMEN.1200 BME Application Programming and Co-req: BMEN.2205L Bioinstrumentation Lab.
This course is the laboratory section associate with Bioinstrumentation (BMEN.2200). The lab will learn how to build basic circuits to collect physiologically-relevant data and analyze the data using concepts from signal processing.
Co-req: BMEN.2200 Bioinstrumentation.
This course provides an introduction to human physiology using a quantitative, systems oriented approach. Systems examined include: musculoskeletal: cardiovascular; respiratory; renal; gastrointestinal; and endocrine. Mathematical models, MATLAB simulation and engineering analyses are used to describe system performance where applicable.
Pre-req: BMEN.2200 Bioinstrumentation, and Co-req: BMEN.3205L Quantitative Physiology Lab.
Experiments involving the modeling and measurement of human physiology systems. Use of computer simulations to provide mathematical descriptions of physiological behavior. Calibration and validation of models through hands-on experiments. Focus on quantitative measurement of neural, cardiovascular, respiratory, muscular, and endocrine system functions.
Co-req: BMEN.3200 Quantitative Physiology, and Pre-req: BMEN.2205L Bioinstrumentation Lab.
This course builds on the work done in BMEN.4030, Medical Device Design I. The course focuses on moving one or more potential solutions to a medical need forward into technical development and preparing for commercialization. Students will learn the fundamentals of medical device prototyping; developing patent strategies; planning for reimbursement and regulatory approval; choosing a commercialization route (licensing, partnering, start - up); anticipating marketing, sales, and distribution needs; understanding financial modeling and cash requirement; fundraising; and identifying and managing risks.
Pre-req: BMEN.4030 Medical Device Design I, or BMEN.5030 Medical Device Development.
A comprehensive and in-depth analysis of US medical device diagnostics development and approval requirements. Detailed analysis of quality assurance issues and regulatory reforms implemented under the Food and Drug Administration. Provides a step-by-step guide through the Center for Devices and Radiological Health (CDRH) investigation device exemptions, premarket approval, 510(k) application process and product development protocol and review process.
Level Junior Standing.
The biomedical properties and structures of polymers determine their utilization in various biomedical applications such as medical devices, implants, drug delivery, and medical packaging. These biomedical properties include mechanical properties, physical properties, chemical properties, optical properties, electrical properties, melt flow properties, failure and fracture properties, viscoelastic properties, and chemical composition.
Pre-req: BMEN.4020 Biomaterials.
The course will introduce principles of cell biology and design underlying cell and tissue engineering decision-making. Students will learn how mechanical and chemical aspects of the extracellular environment influence cell functions including viability, proliferation, differentiation, and protein expression, and how those aspects may be integrated and/or manipulated in vitro and in vivo using various material and chemical approaches. Additionally, students will be introduced to contemporary techniques used to assess engineered tissue response and integration via immunocyto-/histo-chemistry, secretomics, imaging, immunoassays, and sequencing modalities.
Pre-req: BIOL.2100 Biology for Engineers, or BIOL.1110 Principles of Biology I, and CHEM.2210 Organic Chemistry I.
Tissue engineering research continues to attract the interest of researchers and the general public. Popular media outlets like the New York Times, Time, and Wired continue to engage a wide audience and foster excitement for the field as regenerative medicine inches toward becoming a clinical reality. This course will cover enabling technologies, and current applications of the tissue engineering field. The enabling technologies section will focus upon those strategies typically incorporated into tissue-engineered deices or utilized in their development, including advanced scaffolding techniques, bioreactors, and micro physiological systems. Finally, the applications section presents engineered tissues and organs that are currently under development for regenerative medicine applications.
Pre-req: BMEN.4110 Tissue Engineering, or BMEN.5110 Tissue Engineering.
This recitation portion of the co-req course prepares students with the hands-on training required for working in a tissue engineering laboratory, This course will also emphasize selection and implementation of relevant assays and other analytical techniques.
Co-Req BMEN.4120L Tissue Engineering Laboratory
This laboratory course prepares students with the hands-on training required for working in a tissue engineering laboratory, including the development of experimental design and laboratory documentation skills. Experiments emphasizing 3-D tissue culture techniques will be employed. Lab modules are designed for students to achieve competency in skills to be able to design, create and test 3-D tissue cultures for tissue engineering and related biomaterial applications. This course will also emphasize selection and implementation of relevant assays and other analytical techniques. Students will complete a term project that synthesizes and learned skills and requires application of experimental design and data analysis.
Pre-req: BIOL.1170L Principles of Biology I Lab , or BIOL.2120L Biology for Engineers Lab.
Neural Engineering represents the intersection between neuroscience and the technologies designed to measure and modulate the nervous system. This course will review the fundamental principles of cellular and systems neuroscience in the peripheral and central nervous systems, followed by surveys of cutting edge optical/electrical neural interfaces, in vivo/vitro synthetic model systems, prostheses, as well as ethical considerations in neuroscience/neural engineering.
Pre-req: BMEN.2200 Bioinstrumentation, and BMEN.3200 Quantitative Physiology, or Permission of Instructor.
Occupational ergonomics provides us with a scientific basis for designing the work environment to optimize the physical and mental interaction of workers with their work systems: machines, tools, co-workers, work methods, etc. This is a survey of the field, so we will cover a wide variety of topics: relevant principles of anatomy, physiology, and musculoskeletal function; design of the physical and psychosocial work environment to enhance worker health and safety, work scheduling to reduce fatigue, and mental workload (e.g., display of information) to reduce worker error. Wherever relevant we will incorporate basic approaches to hazard assessment, exposure limits or guidelines, and approaches to workplace design.
The course provides an overview of musculoskeletal anatomy, the mechanical properties and structural behavior of biological tissues, and biodynamics. Specific course topics will include structure and function relationships in tissues and organs; application of stress and strain analysis to biological tissues; analysis of forces in human function and movement; energy and power in human activity; introduction to modeling viscoelasticity of tissues.
Pre-req: PHYS.1410 Physics I, and BMEN.1200 BME Applications Programming.
This course prepares students with the mathematical preliminaries and theoretical framework to analyze the mechanics of biological materials and human movement. The course will focus on methods to model biological tissues as non-linear, elastic, homogeneous, anisotropic, incompressible materials, and analyze human movement, including the impulse-momentum and work-energy principles, as well as gait analysis.
Pre-req: BMEN.4310 Biomechanics, and MATH.2340 Differential Equations, or MATH.2360 Eng Differential Equations, or MATH.2440 Honors Differential Equations.
This course will introduce fundamental principles and mathematical/physical models for air and blood flow in the physiological systems. Their practical applications will be discussed, with an emphasis on modeling and the potential of flow studies for clinical research applications.
Pre-req: BMEN.3100 Transport Phenomena for Biomedical Engineering.
An aerosol is an assembly of particles suspended in a gaseous medium. They are omnipresent in our workplaces and outdoor environments. They include a wide range of phenomena such as dust, fume, smoke, mist, fog, haze, clouds, and smog. Certain aerosols pose significant health threats, while others improve the quality of our lives. It is necessary to understand how airborne particles behave to control against their undesirable effects and to harness their beneficial potential. This course will explore the mechanics of aerosol behavior, including their generation, transformation, and fate in occupational and environmental settings.
Pre-req: PHYS.1440 Physics II, and MATH.2310 Calculus III, and Junior Standing or Above.
Computational biomechanics is a powerful engineering method to model fluid-structure interaction in biological systems. While its traditional roots are in the realm of engineering, the techniques have found wide use in the biomedical engineering domain to simulate the biomechanical response and hemodynamics of the human body and medical devices. This course will prepare students with hands-on and practical skills using computational packages and software to solve biomechanical problems.
Pre-req: BMEN.1200 BME App. Programming, and BMEN.3100 Transport Phenomena, and BMEN.4310 Biomechanics I, and MATH.2340 Differential Equations.
This course introduces the student to the use of CAD for construction of basic shapes and multi-view drawings. It is a project-oriented course introducing the student tot graphic design using SolidWorks. Design, analysis and visualization of engineering components and systems using interactive computer programs with an emphasis on computer simulation.
Junior or Senior standing.
This course will introduce fundamental principles of the interactions between light and biological tissue, including their applications in biology and medicine for detection, imaging, and treatment.
Pre-req: BMEN.3100 Transport Phenomena, and BMEN.1200 BME Applications Programming, and MATH.2340 Differential Equations, and PHYS.1440 Physics II, or Permission of Instructor.
Data analysis is a major skill that is required to solve problems as well as to design and develop biotechnology solutions and medical devices. A bioengineer must not only apply the long standard general statistical methods in order to analyze data but also master some of the unique aspects involved in the analysis of biomedical datasets. This course will require the student to become proficient in MATLAB and the Statistics and Machine Learning Toolbox in order to achieve course learning objectives. The student will also be required to demonstrate their bioanalytical proficiency through the implementation of an individual project.
Pre-req: MATH.2830 Introduction to Statistics, or MATH.3860 Probability and Statistics, or Permission of Instructor.
This course will cover successful strategies in project management and mentorship. Students in the course will serve as project managers (PM) and mentors to the students enrolled in BMEN.1070: Introduction to Biomedical Engineering. PMs will facilitate one to two groups in the completion of their semester long project in BMEM.1070. They will set deadlines, assess work, manage the project, and participate in weekly professional development meetings. We will discuss how to run successful meetings, to set achievable goals, and to optimize time and budget constraints in order to ensure successful completion of a BME related project. We will also explore career options as a project manager, learn about their job responsibilities, and learn essential tools commonly used by PMs in industry.
This is the first of a two course capstone sequence. It provides an integrative design experience in engineering. Students work in teams and apply their engineering problem solving skills on open-ended, real-world biomedical projects. This course has an emphasis on team work, communication, report writing, oral presentations, project definition and project planning.
Pre-req: BMEN.3200 Quantitative Physiology, and BMEN.3205L Quantitative Physiology Lab, and Pre- or Co-req: BMEN.3100 Transport Phenomena, and BMEN.4310 Biomechanics.
This is the second of a two course capstone sequence. This course provides an integrative design experience in engineering. Students work in teams and apply their engineering problem solving skills on open-ended, real-world biomedical projects. This course has an emphasis on team work, communication, report writing, oral presentations, design, analysis, test and fabrication.
Pre-req: BMEN.4910 Biomedical Capstone I.
This course will provide an in-depth examination of a specific area of biomedical engineering. Specific topics will vary with the expertise of the instructor.
Junior Standing, or Permission of Instructor.
BME Research Experience I will provide biomedical engineering students with a mentored experience with a hands-on research project. Appropriate research experiences are those within biomedical engineering that allow the student opportunities to increase their skills, knowledge, and experiences in their academic/career goal areas. Student will work approximately 3 hours a week per credit on the designated research project. Regular meetings with the research mentor will also occur. Students are required to submit a significant status update or final project report to their mentor. "Variable credit course, student chooses appropriate amount of credits when registering."
BME Research Experience II will provide biomedical engineering students with a mentored experience in a hands-on research project. The project is expected to be a continuation of the work begun in BME Research Experience I. Appropriate research experiences are those within biomedical engineering that allow the student opportunities to increase their skills, knowledge, and experiences in their academic/career goal areas. Student will work approximately 3 hours a week per credit on the designated research project. Regular meetings with the research mentor will also occur. Students are required to give a departmental seminar on their research project. "Variable credit course, student chooses appropriate amount of credits when registering."
Pre-req: BMEN.4980 BME Research Experience I, and Permission of Instructor.