UMass Lowell - Center for Intelligent Biomaterials

Bioinformatics Software

GENVIS: A UNIX based software platform employing an ORION Database Management System into which additional functions can be incorporated, whose current version can calculate sequence frequencies along DNA using a moving window approach- developed in collaboration with Prof. G. Grinstein's Group, Computer Science department, UML.

MELTSIM version 1.0: A Windows based bioinformatics software tool employing a statistical mechanical algorithm, experimentally parameterized to calculate the melting spectra of long DNA (not oligonucleotides) with files of up to 500,000 bp length. This program also calculates the positional melting behavior along any given DNA sequence. This program was developed in collaboration with Prof. R.D. Blake.

Clustering and Neural net based DNA(exon/intron) and Protein classification algorithms and UNIX Visualization Platform, in collaboration with Prof. G. Grinstein, Computer Science, UML, under funding by Pfizer Central Research Grants Program: "Innovative Grants in Data Analysis".

Open Source software advisor, developer and web server host for The Open Lab (at www.bioinformatics.org), an international bioinformatics software collaboratory developing new bioinformatics software. MELTSIM 1.0 and PolyACGT programs are being made available through this website.

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