Research

The MBMC focuses on applied research problems that improve the quality, cost and productivity of large-scale biomanufacturing production.  The applied research pursues both incremental and breakthrough advances.  Incremental advances include improved process control of bioreactors, increased expression levels, prolonged cell lifetimes and faster cell growth rates (cell cycle times) and disposable and new purification technologies.  Breakthrough programs include perfusion reactors to convert batch processes to continuous ones, developing yeast as a replacement for mammalian cell cultures and using E. coli to create antibodies in soluble form.

First adaptations of our applied research outcomes within a biopharmaceutical manufacturing operation can provide considerable economic advantage to a company.