Printer FriendlyPurification Process Characterization
Case study to be provided soon.
E. COLI Fermentation Development
E. coli is the organism of choice for nonglycosylated recombinant protein production. Proteins can be expressed as inclusion bodies, intracellular soluble protein or periplasmic secreted proteins. E. coli has many advantages for use as a production host.
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FEATURE |
PROCESS BENEFIT |
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Simple nutritional requirements Fast growth rate High cell density Expression as inclusion body Expression as soluble product (intracellular or periplasmic) Absence of human or related viruses |
Low media cost High throughput High productivity Protease stable No refolding required Simplified validations |
Fermentation Development
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Intracellular solublePeriplasmic secreted