This course provides a basic knowledge of the structure and function of the human body. An overview of the general organization of the body introduces the course. Following a discussion of basic human chemistry, the anatomy and physiology of cells, tissues, organs, and organ systems are studied with special emphasis placed on homeostasis and interaction among the various systems. The topics treated are body plan, chemistry, cytology, histology, the integumentary system, the skeletal system, the muscular system, and the nervous system. Clinical applications will be presented.
Co-Requisite: 35.103 Human A & P Lab I
A continuation of the basic knowledge of human structure and function. The topics treated are cardiovascular system, lymphatic system, respiratory system, endocrine system, digestive system, metabolism, urinary system, and reproductive system.
Pre-Req: 35.101 Anatomy & Physiology I and 35.103 Human A & P Lab I or Co-Req: 35.104 Human A & P Lab II
Laboratory exercises are designed to reinforce didactic material by providing hands-on experience with the subject matter. Students actively participate in simple chemical analysis, microscopic observations, and studies of anatomical models and preserved specimens. Students perform simple physiological tests on themselves and work in small groups to discuss conclusions.
Co-Requisite: 35.101 Anatomy & Physiology I
Laboratory exercises are designed to reinforce didactic material by providing hands-on experience with the subject matter. Students actively participate in simple chemical analysis, microscopic observations, and studies of anatomical models and preserved specimens. Students perform simple physiological tests on themselves and work in small groups to analyze results and discuss conclusions.
Co-Requisite: 35.102 Anatomy & Physiology II
This course provides an overview of nutrition and the components of a nutritious diet during the various stages of the life cycle. It emphasizes the impact of nutrition on the major contemporary health problems in the United States. Nutrition issues, trends and research, and their effect on society and the legislative process will be explored.
Course is primarily designed for students with limited experience in the field of nutrition and fitness. The course will introduce students to concepts related to the digestive process, metabolism, nutritional requirements, fitness profiles, fitness prescriptions, weight management, and eating disorders. This survey of relevant topic areas related to nutrition and fitness will prepare students for more advanced nutrition courses.
Studies the fundamentals of microbiology with major emphasis on structure, function, growth, metabolism, and classification of clinically important microorganisms. The human body's response to invading microbes and an introduction to the ecological aspects of microorganisms in the environment with particular stress on their significance, activities (beneficial and detrimental) and control measures will also be studied.
Pre-Req: 35.102 Anatomy & Physiology II and 35.104 Human A & P Lab II and Co-Req: 35.213 Bas Cl Micro & Path Lab
Laboratory investigations of basic properties and characteristics of microorganisms are conducted. Students will perform commonly used techniques for collecting, handling, and studying clinically important microorganisms.
Co-Req: 35.211 Bas Cl Micro & Pathology
This course provides a foundation in basic chemistry for students majoring in the Health Professions. Basic concepts covered include: properties of matter, energy, atomic and molecular structure, isotopes and radioactivity, chemical bonding, chemical formulae and reactions. Quantitative aspects of chemical processes, chemical equilibrium and the behavior of gases, including blood gases and their transport are discussed. Properties of water and solutions are studied and include units of concentration, osmosis, osmolality, and physiological fluid and electrolyte balance. The chemistry of acids, bases and buffers is reviewed with emphasis on physiological buffer systems. Quantitative aspects, acid/base balance, compensatory mechanisms and elementary diagnosis are discussed. The chemistry of inorganic trace elements and their physiological roles are investigated. Concepts of organic chemistry are introduced, including the structure and function of carbon, isomerism and the properties and selected reactions of the major functional groups important in human biochemistry.
Pre-Req: 35.102 Anatomy & Physiology II and Co-Req: 35.253 Physiol Chem Lab I
This course is designed to provide a foundation in basic biochemistry for students majoring in the Health Professions. Selected concepts in organic chemistry are integrated into this framework. Aspects of amino acid and protein structure are studied. The structure and function of enzymes, their effects on reaction energetics and dynamics and the diagnostic uses of enzyme assays in clinical medicine are covered. The plasma proteins, hemoglobin, and the structure and function of miscellaneous cellular proteins are reviewed. The chemistry of the nucleic acids, protein anabolism and catabolism are studied along with selected metabolic disturbances and genetic disease. The structure and chemical properties of the simple and complex carbohydrates and lipids their metabolic pathways and cycles, and selected pathologies are studied in detail. Diagnostic tests relating to carbohydrate and lipid abnormalities are included. The course concludes with a study of chemical communication mechanisms, which includes neurotransmitters, hormonal secretions, and immunoglobulins.
Pre-Req: 35.251 Physiological Chem I and Co-Req: 35.254 Physiol Chemistry Lab II
Laboratory experiments are conducted to complement the material covered in 35.251. Exercises dealing with properties of matter, chemical equations, qualitative analysis, energy, osmosis, chemical equilibrium and acids/bases/buffers will be performed. The qualitative properties of alcohols, aldehydes, ketones, acids and esters will be explored.
Co-Req: 35.251 Physiological Chem I
Laboratory experiments are conducted to complement the material covered in 35.252. The chemistry of the basic biochemical molecules will be explored, including proteins, enzymes, carbohydrates, lipids, and nucleic acids. Selected aspects of metabolism and the assay of clinically significant materials will be studied.
Co-Req: 35.252 Physiological Chem II
This course is designed to introduce the pathological and clinical aspects of human genetics with emphasis on prevention, diagnosis, and treatment of genetic diseases. Mendelian, cellular, and molecular genetics are covered as well as the metabolic basis of inherited diseases. Students learn the principles of genetic counseling and how it integrates with other health care disciplines. Students apply genetic counseling precepts by analyzing a condition occurring in their own family and writing a term report that embodies the results of this research. Cytogenetic disorders, the genetics of cancer, somatic cell genetics, immunogenetics, and the "switching on and off" of genes will also be discussed. The application of laboratory techniques such as autoradiography and electrophoresis to DNA extraction, DNA fingerprinting, automated DNA sequencing, RFLP analysis, PCR amplification, and cloning methodology will be presented. Pre-implantation diagnosis, germ-line alteration, and embryo cloning will also be discussed, as will their legal, ethical, and moral implications. Current progress on the Human Genome Project will also be reported.
Academic Plan Clinical Lab Sciences (BS) Only
This course is designed to introduce the theoretical principles and applications of diagnostic techniques and the procedures of the clinical laboratory including phlebotomy. It will define and describe both qualitative and quantitative, manual and automated laboratory techniques, particularly in hematology.
Academic Plan Clinical Lab Sciences (BS) Only
A laboratory course designed to expose prospective clinical scientists to many of the essentialskills, methods, and procedures basic to professional performance in the clinical laboratory; to explain and demonstrate to students and have them perform these methods; to develop an understanding of these techniques and to provide a technical background, an approach to testing that the student can build upon and use in future courses.
Co-Req: 36.241 Clinical Lab Theory & Physics and Academic Plan Clinical Lab Sciences (BS)
A course designed to introduce students to aspects of the clinical laboratory sciences. Topics include the basic clinical laboratoy, professional organizations and professional issues using discussions, demonstrations, field trips guest lecturers and selected readings.
A study of the cultural, biochemical, genetic, serological and pathogenic characteristics of disease producing microorganisms. Emphasis will be placed on the pathophysiology of the infectious diseases and their relationship to isolation and identification of the pathogenic microorganisms.
Pre-Req: 35.211 Bas Cl Micro & Pathology and 35.213 Bas Cl Micro & Path Lab; Co-Req 36.313
This course is designed to introduce the student to pathogenic microorganisms, media and techniques used in the identification of these organisms. Emphasis will be based upon the isolation, identification and differentiation of pathogenic microorganisms common to man. In addition, quality control and antimicrobial susceptibility testing will be covered.
Pre-Req: 35.211 Bas Cl Micro & Pathology and 35.213 Bas Cl Micro & Path Lab and Co-Req: 36.311 Medical Bacteriology and Academic Plan equals Clinical Lab Sciences (BS), Med Tech Option
A study of the human hematopoietic system and its relationship to other organ systems. Discussions will include morphological and biochemical relationships of erythropoiesis and leukopoiesis in health and disease states. A study of the mechanics of blood coagulation as it relates to health and disease states will also be included.
Pre-Req: 35.102 Anatomy & Physiology II and 35.252 Physiological Chem II and Co-Req: 36.323 Clin Hematology Lab and Academic Plan equals Clinical Lab Sciences (BS)
This course is designed to emphasize current hematological and coagulation procedures used in today's clinical laboratory. The implications of these tests to diagnose, monitor and evaluate the various hematological disorders are also discussed.
Co-Req: 36.321 Clinical Hematology CLS Medical Technology sub-plan student only.
An introduction to the principles of immunology including: the study of antigens and antibodies and their interactions and controls; description of cellular events and the immune response, and in vivo and in vitro antigen-antibody interactions with clinical relevance. Immunological aspects of transplantation, autoimmune disease, immunodeficiencies and cancer pathogenesis are also discussed.
Academic Plan Clinical Lab Sciences (BS) Only
This course surveys the principles of organic chemistry important for the study of clinical chemistry and human biochemistry. The chemistry of carbon compounds, bonding and theconcepts of isomerism will be studied. Detailed information is presented on each of the major functional classes of organic compounds, including: hydrocarbons, halides, alcohol, phenols, ethers, aldehydes, ketones, carboxylic acids and their derivatives, amines, organosulfur compounds. Emphasis is placed on chemical structure, physical and chemical properties, common and IUPAC nomenclature, and chemical reactions and their mechanisms. Selected aspects of the properties and synthesis of polymeric materials are presented. Qualitative analysis of organic compounds is discussed with emphasis on the use of spectral techniques, including infra-red and nuclear magnetic resonance spectroscopy for the elucidation of chemical structure.
Pre-Req: 35.251 Physiological Chem I
Laboratory exercises are performed to supplement the material covered in 36.341.
Co-Req: 36.341 Organic Reac & Structure and Academic Plan equals Clinical Lab Sciences (BS)
This course is an in-depth study of biochemical substances and their reactions in the body, with major emphasis placed on metabolism at the cellular level and examined in the tissues of the various organs where these reactions occur. Correlation of biochemical processes underlying pathologic conditions will be made whenever practical.
Pre-Req: 35.252 Physiological Chem II
This course is designed to provide students with knowledge and theory of techniques used in the Clinical Chemistry laboratory for measurement of aminoacids, proteins, carbohydrates, and lipids in body fluids. Students will learn to use, interpret and evaluate the performance of these laboratory methods and develop the ability to recognize levels of these biochemical components in both normal and pathophysiological states. Examination and comparison of laboratory results will be used to diagnose or rule out disease. Techniques reviewed range from general to specific assays and from the classical to state-of-the-art methodologies. In addition, students will be able to assess the quality of laboratory generated values determine when values are invalid and suggest ideas to troubleshoot clinical laboratory methods.
Pre-Req: 36.341 Organic Reac & Structure and 36.350 Human Biochemistry and 36.361 Clin Lab Instrumentation and Academic Plan is Clinical Lab Sciences (BS) and Co-Req: 36.353 Clinical Chemistry Lab
This course is designed to introduce the clinical techniques of biochemical measurement in body fluids. These techniques range from general to specific assays and from the classical to the upto- date state of the art methodologies. Biochemical measurements of the following in the normal state and alterations due to pathophysiology are discussed: amino acids, proteins, carbohydrates and lipids. Quality control of assay procedures is emphasized.
Academic Plan Clinical Lab Sciences (BS) and Co-Req: 36.351 Clinical Chemistry I
This course is designed to provide an in-depth knowledge of clinical chemistry laboratory instrumentation. Emphasis is placed on theoretical concepts, instrument components and design, calibration and troubleshooting of modern instrumentation, and analytical methodologies in the clinical laboratory. Additionally, qualitative and quantitative applications of instrumental techniques are covered. Computer applications are included where appropriate. The following spectroscopic instruments are studied: ultraviolet, visible and infra red absorption, fluorescence, turbidimetry and nephelometry, reflectance, flame emission and atomic absorption spectroscopy. Electrochemical methods of analysis are reviewed, including potentiometric techniques, voltammetry and coulometry. Chromatographic instrumentation and methods are discussed, such as column and thin layer chromatography, high pressure liquid chromatography, gas chromatography, and ion exchange chromatography.
Pre-Req: 35.252 Physiological Chem II and Academic Plan Clinical Lab Sciences (BS)
Laboratory exercises will be performed to supplement the material covered in 36.361.
Co-Req: 36.361 Clin Lab Instrumentation and Academic Plan Clinical Lab Sciences (BS)
Detailed analysis of the digestion, absorption, transport, and intermediary metabolism of nutrients. Nutrient requirements are evaluated in the context of their physiological and biochemical functions.
Prerequisites: 35.206
Pre-Req: 35.206 Human Nutrition, or 30.206 Human Nutrition
Etiology, pathophysiology, and treatments of obesity, anorexia nervosa, and bulimia are reviewed. Role of hereditary, neurological, metabolic, and environmental mechanisms are discussed. Particular emphasis on obesity.
Pre-Req: 35.206 Human Nutrition, or 30.206 Human Nutrition
This course is designed to familiarize the student with different interview skills and approaches to resume writing, the process of implementing a laboratory information system, good education practices and team building skills. Students will evalate current research designs and work in a team to create a presentation to express their opinions as educated consumers.
Academic Plan Clinical Lab Sciences (BS) Only
This advanced course in the nutritional biochemistry and physiology of lipids will detail the role of lipids in the normal and pathological processes at both the cellular and whole organism level. Topics will range from general discussions of the digestion, absorption and transport of lipids to the role of eicosanoids and lipid soluble antioxidants during normal and diseased states, such as atherosclerosis, diabetes and hypertension. Subject matter will also include a discussion of the various interventions for the prevention and treatment of certain of these disease states. There will also be discussion of the current issues in lipid nutrition.
Pre-Req: 35.206 Human Nutrition and 36.350 Human Biochemistry
Supervised clinical training in an affiliated clinical laboratory, designed to reinforce knowledge and skills gained in lecture and laboratory and at the same time introduce the student to the daily activities of the clinical microbiology laboratory. Emphasis will be placed on quality control, methodology and clinical interpretation.
Pre-Req: 36.311 Medical Bacteriology and 36.313 Medical Bacteriology Lab and Academic Plan equals Clinical Lab Sciences (BS)
Intensive study of classification, morphology, physiology, genetics and ecology of medically important fungi and parasites. Emphasis on epidemiology, pathogenicity and diagnosis.
Pre-Req: 36.311 & 313 Medical Bacteriology w/lab; and Co-Req: 36.413 Med Mycology & Para Lab
The laboratory is designed to emphasize principles and procedures used in the isolation, cultivation, and identification of medically important fungi and parasites.
Co-Req: 36.411 Med Mycology & Para or 36.615 Medical Parasitology and Academic Plan Clinical Lab Sciences (BS)
This course is designed to survey pathogenic viruses emphasizing diagnosis of disease. Evaluation of new technology and diagnostic tests with reference to diagnosis and prognosis of disease are examined. In addition, this course is designed to instruct students in the principles and techniques used in the clinical immunology/serology setting. Students will become proficient in laboratory techniques such as immunodiffusion, ELISA, hemagglutination, and neutralization techniques used for immunodiagnosis.. "
Pre-Req: 36.331 Clinical Immunology and Academic Plan Clinical Lab Sciences (BS)
This course is designed to instruct students in the principles and techniques used in molecular diagnostics settings. Students will become proficient in PCR, Western Blot, Southern Blot and other laboratory methods used for molecular diagnostics.
Co-Req: 35.435 Medical & Clin Genetics and Academic Plan Clinical Lab Sciences (BS)
Supervised clinical training in an affiliated clinical laboratory. Designed to reinforce knowledge and skills gained in lecture and laboratory and at the same time introduce the student to the daily activities of a clinical hematology laboratory. Emphasis will be placed on quality control, methodology, and clinical interpretation and correlation.
Pre-Req: 36.321 Clinical Hematology and 36.323 Clin Hematology Lab and Academic Plan equals Clinical Lab Sciences (BS)
Supervised clinical training in an affiliated clinical laboratory is designed to reinforce knowledgeand skills gained in lecture and laboratory and, at the same time, introduce the student to thedaily activities of the clinical immunohematology laboratory. Emphasis will be placed on quality control, methodology and clinical interpretation and correlation.
Pre-Req: 36.431 Cl Immunohematology or 36.531 Clinical Immunohmatology and 36.433 Cl Immunohematology Lab and Academic Plan equals Clinical Lab Sciences (BS)
Lecture and case study discussions look at the major red cell antigen/antibody systems that are of importance in understanding transfusion therapies, blood antigen and antiody testing, compatibility testing, and pathological diseases. Emphasis is on differentiation and clinical significance of each system. Donor selection regulations, component preparation, adverse transfusion reactions, and hematherapy will also be discussed.
Pre-Req: 36.321 Clinical Hematology, 36.331 Clinical Immunology, and CLS majors only.
Practical laboratory experience in blood banking, illustrating the concepts stressed in the lecture including ABO and Rh typing,identification of other red cell antigens, antibody screening and identification, direct antiglobulin testing, crossmatching, and other techniques performed in the Clinical Immunohematology laboratory.
Co-Req: 36.431 Cl Immunohematology or 36.531 Clinical Immunohmatology and Academic Plan equals Clinical Lab Sciences (BS)
This course will constitute an in depth study of the hemostatic mechanism. Current research and case studies on the roles of vessel endothelium, platelet function, clotting procoagulants and fibrinolysis will be presented. Students will diagnose pathologic hemostatic states, such as hemorrhage or thrombophilia, due to deficiencies and impairments of these roles, including the impact of natural and acquired anticoagulants/inhibitors and anticoagulant therapy.
Pre-Req: 36.321 Clinical Hematology
Supervised clinical training in an affiliated hospital clinical laboratory. Designed to reinforce knowledge and skills gained in lecture and laboratory and at the same time introduce the student to the daily activities of the clinical laboratory. Emphasis will be placed on quality control,methodology and clinical interpretation and correlation.
Pre-Req: 36.452 Clinical Chemistry II and 36.454 Clinical Chemistry Lab II and 36.353 Clinical Chemistry Lab and Academic Plan Clinical Lab Sciences (BS)
A one-week clinical rotation in an affiliated laboratory designed to give the student experience in microscopic examination and evaluation of urine sediments. Emphasis is on correlating physical and chemical characteristics with sediment evaluation and diagnoses as well as on quality control, methodology, and clinical interpretation and correlation. Additional routine tests of a physical and chemical nature will be performed and demonstrated.
Co-Req: 36.454 Clinical Chemistry Lab II and 36.452 Clinical Chemistry II and Academic Plan equals Clinical Lab Sciences (BS)
This course will provide students with knowledge and theory of techniques associated with determinants of acid-base balance, blood gases, electrolytes, osmolality, hemoglobin, toxicology, therapeutic drug monitoring and endocrinology. Students learn to interpret and evaluate the performance of these laboratory methods and develop the ability to recognize levels of these biochemical components in both normal and pathophysiological states. Laboratory techniques range from general to specific assays and from the classical to state-of-the-art methodologies. In addition, students will be able to assess the quality and validity of laboratory generated values, determine when values are invalid and suggest ideas to troubleshoot methodologies. Students will also be able to produce and analyze statistical data for use in correlation, comparison and evaluation of laboratory techniques.
Prerequisite: 35.351
Pre-Req: 36.351 Clinical Chemistry I
This course will acquaint the student with the many managerial, educational, technical, and administrative theories and practices, as well as moral and ethical issues that may confront the health care professional functioning within a clinical or research laboratory setting. In addition, it will present the varied career opportunities that are available for graduates.
Academic Plan Clinical Lab Sciences (BS) Only
This course, a continuation of 36.353, is designed to instruct the student in the analytical procedures and methods currently used in the clinical laboratory. Manual and automated methods utilized in the assessment of such topics as acid-base balance, porphyrins, toxicology and vitamins will be introduced. In addition, methods associated with the routine examinations of urine and other body fluids will be introduced. Quality control, laboratory safety and professional performance are emphasized.
Co-Req: 36.452 Clinical Chemistry II and Academic Plan equals Clinical Lab Sciences (BS)
Detailed analysis of the digestion, absorption, transport, and intermediary metabolism of vitamins and minerals as essential nutrients. The chemical and biochemical characteristics of vitamins and minerals are examined to account for the physiological functions.
Pre-Req: 35.206 Human Nutrition and 36.350 Human Biochemistry
This course provides the student the the opportunity to assess nutritional status using several modern analytical methods. The course uses spectrophotometry, HPLC and automated procedures to assess the status of vitamins, lipids, iron, glucose, and insulin. The student will learn the mathematical calculations needed for the methods. This course enables the student to appreciate how nutrient analysis is designed and implemented in the analytical laboratory.
Regulation of eukaryotic gene expression by specific nutrients, hormones, and metabolites will be discussed. Transcriptional, post-transcriptional, and translational mechanisms of specific nutrients with emphasis in disease development or prevention.
Pre-Req: 35.206 Human Nutrition, or 30.206 Human Nutrition
This course is designed to familiarize the student with different types of questions used in the national certification exams and to give the student the opportunity to practice taking mock certification examinations.
Academic Plan Clinical Lab Sciences (BS) Only
Principles of normal nutrition and physiology applied to clinical problems; altered nutrient requirements in human disease. A study of topics of current clinical interest.
Prerequisite: 36.371
Pre-Req: 35.206 Human Nutrition, or 30.206 Human Nutrition
Students along with their faculty advisor will structure a research project commensurate with the students' areas of interest. A paper embodying the results of the research project will be prepared.
Academic Plan Clinical Lab Sciences (BS) Only
Continuation of 36.483
Academic Plan Clinical Lab Sciences (BS) Only
Students along with their faculty advisor will structure an acceptable project in one of four areas: research, program development, teaching, or clinical practicum. Students are eligible to earn three credits in accordance with departmental policy.
Academic Plan Clinical Lab Sciences (BS) Only
Students with their faculty advisor structure a research project in the area of nutrition. A paper embodying the results of the project will be prepared.
Academic Sub-Plan Nutrition only
Continuation of 36.494.
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