Undergraduate Course Catalog

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35.101	Human Anatomy and Physiology I	Credits: 3
This course provides a basic knowledge of the structure and function of the human body. An overview of the general organization of the body introduces the course. Following a discussion of basic human chemistry, the anatomy and physiology of cells, tissues, organs, and organ systems are studied with special emphasis placed on homeostasis and interaction among the various systems. The topics treated are body plan, chemistry, cytology, histology, the integumentary system, the skeletal system, the muscular system, and the nervous system. Clinical applications will be presented.
35.102	Human Anatomy and Physiology II	Credits: 3
A continuation of the basic knowledge of human structure and function. The topics treated are cardiovascular system, lymphatic system, respiratory system, endocrine system, digestive system, metabolism, urinary system, and reproductive system.
35.103	Human Anatomy and Physiology Laboratory I	Credits: 1
Laboratory exercises are designed to reinforce didactic material by providing hands-on experience with the subject matter. Students actively participate in simple chemical analysis, microscopic observations, and studies of anatomical models and preserved specimens. Students perform simple physiological tests on themselves and work in small groups to discuss conclusions.
35.104	Human Anatomy and Physiology Laboratory II	Credits: 1
Laboratory exercises are designed to reinforce didactic material by providing hands-on experience with the subject matter. Students actively participate in simple chemical analysis, microscopic observations, and studies of anatomical models and preserved specimens. Students perform simple physiological tests on themselves and work in small groups to analyze results and discuss conclusions.
35.107	Bodies and Bones	Credits: 3
This course is open only to high school students accepted to the UML TEAMS Academy. This course uses an investigative approach to examine concepts related to the fields of Anatomy and Biochemistry. Select topics will be studied and applied to clinical situations and forensic cases. Assessment techniques will be used in hands-on laboratory activities and forensic simulations. The course will emphasize investigations using the scientific method, observation, and critical analysis. This course is open only to high school students accepted to the UML TEAMS Academy.
35.205	Introduction to Nutritional Science	Credits: 3
This course introduces students to the major in Nutritional Science. Objectives of the major are covered along with beginning nutritional and food science principles, history of the profession, career options, and legal aspects of practice as a nutrition educator. An integrated survey of nutrition science as it relates to human physiological chemistry, food chemistry and biochemistry will also be discussed. This course will include guest speakers from within the department and outside the university. This course will be restricted to nutritional science majors.
35.206	Human Nutrition	Credits: 3
This course provides an overview of nutrition and the components of a nutritious diet during the various stages of the life cycle. It emphasizes the impact of nutrition on the major contemporary health problems in the United States. Nutrition issues, trends and research, and their effect on society and the legislative process will be explored.
35.207	Fitness and Nutrition	Credits: 3
Course is primarily designed for students with limited experience in the field of nutrition and fitness. The course will introduce students to concepts related to the digestive process, metabolism, nutritional requirements, fitness profiles, fitness prescriptions, weight management, and eating disorders. This survey of relevant topic areas related to nutrition and fitness will prepare students for more advanced nutrition courses.
35.211	Basic Clinical Microbiology & Pathology	Credits: 3
Studies the fundamentals of microbiology with major emphasis on structure, function, growth, metabolism, and classification of clinically important microorganisms. The human body's response to invading microbes and an introduction to the ecological aspects of microorganisms in the environment with particular stress on their significance, activities (beneficial and detrimental) and control measures will also be studied.
35.213	Basic Clinical Microbiology & Pathology Laboratory	Credits: 1
Laboratory investigations of basic properties and characteristics of microorganisms are conducted. Students will perform commonly used techniques for collecting, handling, and studying clinically important microorganisms.
36.241	Clinical Laboratory Theory	Credits: 3
This course is designed to introduce the theoretical principles and applications of diagnostic techniques and the procedures of the clinical laboratory including phlebotomy. It will define and describe both qualitative and quantitative, manual and automated laboratory techniques, particularly in hematology.
36.243	Clinical Laboratory Theory Lab	Credits: 1
A laboratory course designed to expose prospective clinical scientists to many of the essentialskills, methods, and procedures basic to professional performance in the clinical laboratory; to explain and demonstrate to students and have them perform these methods; to develop an understanding of these techniques and to provide a technical background, an approach to testing that the student can build upon and use in future courses.
35.251	Physiological Chemistry I	Credits: 3
This course provides a foundation in basic chemistry for students majoring in the Health Professions. Basic concepts covered include: properties of matter, energy, atomic and molecular structure, isotopes and radioactivity, chemical bonding, chemical formulae and reactions. Quantitative aspects of chemical processes, chemical equilibrium and the behavior of gases, including blood gases and their transport are discussed. Properties of water and solutions are studied and include units of concentration, osmosis, osmolality, and physiological fluid and electrolyte balance. The chemistry of acids, bases and buffers is reviewed with emphasis on physiological buffer systems. Quantitative aspects, acid/base balance, compensatory mechanisms and elementary diagnosis are discussed. The chemistry of inorganic trace elements and their physiological roles are investigated. Concepts of organic chemistry are introduced, including the structure and function of carbon, isomerism and the properties and selected reactions of the major functional groups important in human biochemistry.
35.252	Physiological Chemistry II	Credits: 3
This course is designed to provide a foundation in basic biochemistry for students majoring in the Health Professions. Selected concepts in organic chemistry are integrated into this framework. Aspects of amino acid and protein structure are studied. The structure and function of enzymes, their effects on reaction energetics and dynamics and the diagnostic uses of enzyme assays in clinical medicine are covered. The plasma proteins, hemoglobin, and the structure and function of miscellaneous cellular proteins are reviewed. The chemistry of the nucleic acids, protein anabolism and catabolism are studied along with selected metabolic disturbances and genetic disease. The structure and chemical properties of the simple and complex carbohydrates and lipids their metabolic pathways and cycles, and selected pathologies are studied in detail. Diagnostic tests relating to carbohydrate and lipid abnormalities are included. The course concludes with a study of chemical communication mechanisms, which includes neurotransmitters, hormonal secretions, and immunoglobulins.
35.253	Physiological Chemistry Laboratory I	Credits: 1
Laboratory experiments are conducted to complement the material covered in 35.251. Exercises dealing with properties of matter, chemical equations, qualitative analysis, energy, osmosis, chemical equilibrium and acids/bases/buffers will be performed. The qualitative properties of alcohols, aldehydes, ketones, acids and esters will be explored.
35.254	Physiological Chemistry Laboratory II	Credits: 1
Laboratory experiments are conducted to complement the material covered in 35.252. The chemistry of the basic biochemical molecules will be explored, including proteins, enzymes, carbohydrates, lipids, and nucleic acids. Selected aspects of metabolism and the assay of clinically significant materials will be studied.
36.273	Introduction to Clinical Laboratory Science	Credits: 2
This course is intended to provide the student with an overview of the medical laboratory. Topics include the history of the field, hospital and laboratory professional organizations, state and federal regulations, and careers in the clinical setting, in research and in industry. The role of the medical laboratory scientist in the clinical setting will be explored further through examination of each laboratory department.
36.311	Medical Bacteriology I	Credits: 3
A study of the cultural, biochemical, genetic, serological and pathogenic characteristics of disease producing microorganisms. Emphasis will be placed on the pathophysiology of the infectious diseases and their relationship to isolation and identification of the pathogenic microorganisms.
36.313	Medical Bacteriology Laboratory I	Credits: 2
This course is designed to introduce the student to pathogenic microorganisms, media and techniques used in the identification of these organisms. Emphasis will be based upon the isolation, identification and differentiation of pathogenic microorganisms common to man. In addition, quality control and antimicrobial susceptibility testing will be covered.
36.321	Clinical Hematology	Credits: 3
A study of the human hematopoietic system and its relationship to other organ systems. Discussions will include morphological and biochemical relationships of erythropoiesis and leukopoiesis in health and disease states. A study of the mechanics of blood coagulation as it relates to health and disease states will also be included.
36.323	Clinical Hematology Laboratory	Credits: 2
This course is designed to emphasize current hematological and coagulation procedures used in today's clinical laboratory. The implications of these tests to diagnose, monitor and evaluate the various hematological disorders are also discussed.
36.331	Clinical Immunology	Credits: 3
An introduction to the principles of immunology including: the study of antigens and antibodies and their interactions and controls; description of cellular events and the immune response, and in vivo and in vitro antigen-antibody interactions with clinical relevance. Immunological aspects of transplantation, autoimmune disease, immunodeficiencies and cancer pathogenesis are also discussed.
36.341	Organic Reactions & Structure	Credits: 3
This course surveys the principles of organic chemistry important for the study of clinical chemistry and human biochemistry. The chemistry of carbon compounds, bonding and theconcepts of isomerism will be studied. Detailed information is presented on each of the major functional classes of organic compounds, including: hydrocarbons, halides, alcohol, phenols, ethers, aldehydes, ketones, carboxylic acids and their derivatives, amines, organosulfur compounds. Emphasis is placed on chemical structure, physical and chemical properties, common and IUPAC nomenclature, and chemical reactions and their mechanisms. Selected aspects of the properties and synthesis of polymeric materials are presented. Qualitative analysis of organic compounds is discussed with emphasis on the use of spectral techniques, including infra-red and nuclear magnetic resonance spectroscopy for the elucidation of chemical structure.
36.343	Organic Reactions & Structure Laboratory	Credits: 1
Laboratory exercises are performed to supplement the material covered in 36.341.
36.345	Community Nutrition	Credits: 3
This course explores the role of the nutrition professional in community needs assessment, intervention development and evaluation, and in forming domestic nutrition policy. Nutrition problems in contemporary communities and of selected target groups in the United States and in developing countries are examined. Programs and strategies to meet nutrition needs outside the acute care setting, such as nutrition education and food assistance are explored. Local, state,and national nutrition policy and initiatives in nutrition will also be examined.
36.350	Human Biochemistry	Credits: 3
This course is an in-depth study of biochemical substances and their reactions in the body, with major emphasis placed on metabolism at the cellular level and examined in the tissues of the various organs where these reactions occur. Correlation of biochemical processes underlying pathologic conditions will be made whenever practical.
36.351	Clinical Chemistry I	Credits: 3
This course is designed to provide students with knowledge and theory of techniques used in the Clinical Chemistry laboratory for measurement of aminoacids, proteins, carbohydrates, and lipids in body fluids. Students will learn to use, interpret and evaluate the performance of these laboratory methods and develop the ability to recognize levels of these biochemical components in both normal and pathophysiological states. Examination and comparison of laboratory results will be used to diagnose or rule out disease. Techniques reviewed range from general to specific assays and from the classical to state-of-the-art methodologies. In addition, students will be able to assess the quality of laboratory generated values determine when values are invalid and suggest ideas to troubleshoot clinical laboratory methods.
36.353	Clinical Chemistry Laboratory I	Credits: 2
This course is designed to introduce the clinical techniques of biochemical measurement in body fluids. These techniques range from general to specific assays and from the classical to the upto- date state of the art methodologies. Biochemical measurements of the following in the normal state and alterations due to pathophysiology are discussed: amino acids, proteins, carbohydrates and lipids. Quality control of assay procedures is emphasized.
36.361	Clinical Laboratory Instrumentation	Credits: 3
This course is designed to provide an in-depth knowledge of clinical chemistry laboratory instrumentation. Emphasis is placed on theoretical concepts, instrument components and design, calibration and troubleshooting of modern instrumentation, and analytical methodologies in the clinical laboratory. Additionally, qualitative and quantitative applications of instrumental techniques are covered. Computer applications are included where appropriate. The following spectroscopic instruments are studied: ultraviolet, visible and infra red absorption, fluorescence, turbidimetry and nephelometry, reflectance, flame emission and atomic absorption spectroscopy. Electrochemical methods of analysis are reviewed, including potentiometric techniques, voltammetry and coulometry. Chromatographic instrumentation and methods are discussed, such as column and thin layer chromatography, high pressure liquid chromatography, gas chromatography, and ion exchange chromatography.
36.363	Clinical Laboratory Instrumentation Laboratory	Credits: 2
Laboratory exercises will be performed to supplement the material covered in 36.361.
36.371	Nutrition and Metabolism	Credits: 3
This class is advancement into the biochemical and physiologic process through which the nourishment of the human organism is accomplished and how the interactions among nutrients, other aspects of the environment, and the body result in perturbations affecting human health. The process of human nourishment proceeds within the context of an organism with an intricate structure, unique composition, and specific capacities for adaptive change. Basic information from many disciplines relating to body function and structure will be summarized. This will serve as setting the stage for detailed discussions, which describe the nutritional biochemistry and metabolism of the body for the normal state, and for states where nutrient availability is altered of disease is imposed. Prerequisites: 35.206
36.372	Obesity & Weight Control	Credits: 3
Etiology, pathophysiology, and treatments of obesity, anorexia nervosa, and bulimia are reviewed. Role of hereditary, neurological, metabolic, and environmental mechanisms are discussed. Particular emphasis on obesity.
36.373	Clinical Laboratory Sciences Seminar	Credits: 1
This course is designed to familiarize the student with different interview skills and approaches to resume writing, the process of implementing a laboratory information system, good education practices and team building skills. Students will evalate current research designs and work in a team to create a presentation to express their opinions as educated consumers.
36.406	Biochemistry of Lipids	Credits: 3
This advanced course in the nutritional biochemistry and physiology of lipids will detail the role of lipids in the normal and pathological processes at both the cellular and whole organism level. Topics will range from general discussions of the digestion, absorption and transport of lipids to the role of eicosanoids and lipid soluble antioxidants during normal and diseased states, such as atherosclerosis, diabetes and hypertension. Subject matter will also include a discussion of the various interventions for the prevention and treatment of certain of these disease states. There will also be discussion of the current issues in lipid nutrition.
36.410	Clinical Microbiology Practicum	Credits: 2
Supervised clinical training in an affiliated clinical laboratory, designed to reinforce knowledge and skills gained in lecture and laboratory and at the same time introduce the student to the daily activities of the clinical microbiology laboratory. Emphasis will be placed on quality control, methodology and clinical interpretation.
36.411	Medical Mycology & Parasitology	Credits: 3
Intensive study of classification, morphology, physiology, genetics and ecology of medically important fungi and parasites. Emphasis on epidemiology, pathogenicity and diagnosis.
36.413	Medical Mycology & Parasitology Laboratory	Credits: 2
The laboratory is designed to emphasize principles and procedures used in the isolation, cultivation, and identification of medically important fungi and parasites.
36.415	Clinical Virology/Serology Lab	Credits: 2
This course is designed to survey pathogenic viruses emphasizing diagnosis of disease. Evaluation of new technology and diagnostic tests with reference to diagnosis and prognosis of disease are examined. In addition, this course is designed to instruct students in the principles and techniques used in the clinical immunology/serology setting. Students will become proficient in laboratory techniques such as immunodiffusion, ELISA, hemagglutination, and neutralization techniques used for immunodiagnosis.. "
36.416	Molecular Diagnostics Lab	Credits: 1
This course is designed to instruct students in the principles and techniques used in Molecular Diagnostics in the clinical laboratory setting. Students will be given both lecture and laboratory instruction in basic molecular testing methodologies. At the completion of this course, the student will have a basic understanding of molecular diagnostic principles and will be proficient in molecular diagnostic laboratory techniques including DNA extraction, PCR using SINEs and STRs, restriction enzyme digestion, ELISA, bacterial transformation, DNA sequencing and microarrays.
36.420	Clinical Hematology Practicum	Credits: 2
Supervised clinical training in an affiliated clinical laboratory. Designed to reinforce knowledge and skills gained in lecture and laboratory and at the same time introduce the student to the daily activities of a clinical hematology laboratory. Emphasis will be placed on quality control, methodology, and clinical interpretation and correlation.
36.430	Clinical Immunohematology Practicum	Credits: 2
Supervised clinical training in an affiliated clinical laboratory is designed to reinforce knowledgeand skills gained in lecture and laboratory and, at the same time, introduce the student to thedaily activities of the clinical immunohematology laboratory. Emphasis will be placed on quality control, methodology and clinical interpretation and correlation.
36.431	Clinical Immunohematology	Credits: 3
Lecture and case study discussions look at the major red cell antigen/antibody systems that are of importance in understanding transfusion therapies, blood antigen and antiody testing, compatibility testing, and pathological diseases. Emphasis is on differentiation and clinical significance of each system. Donor selection regulations, component preparation, adverse transfusion reactions, and hematherapy will also be discussed.
36.433	Clinical Immunohematology Laboratory	Credits: 2
Practical laboratory experience in blood banking, illustrating the concepts stressed in the lecture including ABO and Rh typing,identification of other red cell antigens, antibody screening and identification, direct antiglobulin testing, crossmatching, and other techniques performed in the Clinical Immunohematology laboratory.
36.434	Advanced Topics in Hemostasis	Credits: 1
This course will constitute an in depth study of the hemostatic mechanism. Current research and case studies on the roles of vessel endothelium, platelet function, clotting procoagulants and fibrinolysis will be presented. Students will diagnose pathologic hemostatic states, such as hemorrhage or thrombophilia, due to deficiencies and impairments of these roles, including the impact of natural and acquired anticoagulants/inhibitors and anticoagulant therapy.
35.435	Medical & Clinical Genetics	Credits: 3
This course covers the clinical and pathological aspects of human genetics with emphasis on prevention, diagnosis, and treatment of genetic diseases. Mendelian, cellular, and molecular genetics are reviewed, as is the metabolic basis of inherited diseases. Students learn principles of genetic counseling and how they integrate with other health care disciplines. These genetic counseling precepts are applied when students research and analyze a condition occurring in their own family, and write a report that embodies the results of this research. Following a review of DNA chemistry and dynamics, molecular alterations that cause human diseases is extensively discussed, including SNP activity, gene therapy techniques, and epigenetic mechanisms. Transcription and translation, the "switching on and off" of genes, and other DNA activity is discussed. The genetics of cancer, somatic cell genetics, and immunogenetics are integrated into genetic counseling. Laboratory techniques such as autoradiography, DNA extraction and analysis by electrophoresis, DNA profiling, automated DNA sequencing, RFLP analysis, PCR amplification, microarray analysis, and cloning methodology are presented. Pre-implantation diagnosis, germ-line alteration, and embryo cloning will also be discussed, along with their legal, ethical, and moral implications. Current progress on the Human Proteome, Transcriptome, and Kinome Projects will also be reported. Applications of genomics will be pervasive throughout the course.
36.450	Clinical Chemistry Practicum	Credits: 2
Supervised clinical training in an affiliated hospital clinical laboratory. Designed to reinforce knowledge and skills gained in lecture and laboratory and at the same time introduce the student to the daily activities of the clinical laboratory. Emphasis will be placed on quality control,methodology and clinical interpretation and correlation.
36.451	Urinalysis Practicum	Credits: 0
A one-week clinical rotation in an affiliated laboratory designed to give the student experience in microscopic examination and evaluation of urine sediments. Emphasis is on correlating physical and chemical characteristics with sediment evaluation and diagnoses as well as on quality control, methodology, and clinical interpretation and correlation. Additional routine tests of a physical and chemical nature will be performed and demonstrated.
36.452	Clinical Chemistry II	Credits: 3
This course will provide students with knowledge and theory of techniques associated with determinants of acid-base balance, blood gases, electrolytes, osmolality, hemoglobin, toxicology, therapeutic drug monitoring and endocrinology. Students learn to interpret and evaluate the performance of these laboratory methods and develop the ability to recognize levels of these biochemical components in both normal and pathophysiological states. Laboratory techniques range from general to specific assays and from the classical to state-of-the-art methodologies. In addition, students will be able to assess the quality and validity of laboratory generated values, determine when values are invalid and suggest ideas to troubleshoot methodologies. Students will also be able to produce and analyze statistical data for use in correlation, comparison and evaluation of laboratory techniques. Prerequisite: 35.351
36.453	Laboratory Management and Ethics	Credits: 2
This course will acquaint the student with the many managerial, educational, technical, and administrative theories and practices, as well as moral and ethical issues that may confront the health care professional functioning within a clinical or research laboratory setting. In addition, it will present the varied career opportunities that are available for graduates.
36.454	Clinical Chemistry Laboratory II	Credits: 2
This course, a continuation of 36.353, is designed to instruct the student in the analytical procedures and methods currently used in the clinical laboratory. Manual and automated methods utilized in the assessment of such topics as acid-base balance, porphyrins, toxicology and vitamins will be introduced. In addition, methods associated with the routine examinations of urine and other body fluids will be introduced. Quality control, laboratory safety and professional performance are emphasized.
36.463	Vitamins and Minerals	Credits: 3
Detailed analysis of the digestion, absorption, transport, and intermediary metabolism of vitamins and minerals as essential nutrients. The chemical and biochemical characteristics of vitamins and minerals are examined to account for the physiological functions.
36.465	Lab Methods in Nutrition Assessment	Credits: 3
This course provides the student the the opportunity to assess nutritional status using several modern analytical methods. The course uses spectrophotometry, HPLC and automated procedures to assess the status of vitamins, lipids, iron, glucose, and insulin. The student will learn the mathematical calculations needed for the methods. This course enables the student to appreciate how nutrient analysis is designed and implemented in the analytical laboratory.
36.472	Nutrition and Gene Expression	Credits: 3
Regulation of eukaryotic gene expression by specific nutrients, hormones, and metabolites will be discussed. Transcriptional, post-transcriptional, and translational mechanisms of specific nutrients with emphasis in disease development or prevention.
36.474	Senior Seminar	Credits: 1
This course is designed to familiarize the student with different types of questions used in the national certification exams and to give the student the opportunity to practice taking mock certification examinations.
36.481	Medical Nutrition Therapy I	Credits: 3
This course is intended to provide students with current knowledge and application in dietary prevention, treatment, and long-term management of obesity, diabetes, cardiovascular diseases, and upper gastrointestinal diseases. Topics include nutrition counseling and communication skills, professional ethics, medical terminology, clinical laboratory values, dietary menu planning and analysis in specific situations, evaluating nutritional status, case studies for these diseases. This course will stress the steps in the nutrition care process, determine appropriate methods for screening patients for nutritional risk, and help the student assess the nutritional status of patients.
36.482	Medical Nutrition Therapy II	Credits: 3
This course is a continuation of Medical Nutrition Therapy I that will provide students with current knowledge and application in dietary prevention, treatment, and long-term management of patients with trauma, burns, HIV, cancer, liver, lower gastrointestinal diseases, celiac disease, and renal diseases. Topics include nutrition counseling and communication skills, professional ethics, medical terminology, clinical laboratory values, dietary menu planning and analysis in specific situations, evaluating nutritional status, case studies for these diseases, and will examine enteral and parental nutrition support for critically ill patients. Students will also develop a basic knowledge related tot the principles of fluid and electrolytes balance as well as acid-base balance as they relate to the nutritional care of patients/clients.
36.483	Senior Research	Credits: 2
Students along with their faculty advisor will structure a research project commensurate with the students' areas of interest. A paper embodying the results of the research project will be prepared.
36.484	Senior Research	Credits: 2
Continuation of 36.483
36.493	Clinical Laboratory Sciences Directed Studies	Credits: 3
Students along with their faculty advisor will structure an acceptable project in one of four areas: research, program development, teaching, or clinical practicum. Students are eligible to earn three credits in accordance with departmental policy.
36.494	Directed Research in Nutrition	Credits: 3
Students with their faculty advisor structure a research project in the area of nutrition. A paper embodying the results of the project will be prepared.
36.496	Senior Research in Nutrition	Credits: 3
Continuation of 36.494.