Susan Braunhut's Research Laboratory

Publications

This page is in the process of being updated to reflect the recent publications that have been accepted and published. Please check back soon for a complete list of full-length publications.

Book Chapters:

  • D'Amore, P. and Braunhut, S.J. Stimulatory and inhibitory factors in vascular growth control. In Endothelial Cells, Ryan U, ed. CRC Press, Inc., Boca Raton, FL. 13-36. 1988.
  • Braunhut, S.J. Radiation Damage to Vascular Tissue. In Radioprotectors: Chemical, Biological and Clinical Perspective. Malaker, K. and Bump, E. CRC Press, NY, 325-341. 1997.

Selected Referred Full-length Publications:

  • Wang G, Dewilde A, Zhang J, Pal A, Vashist M, Bello D, Braunhut S, Marx K, Therrien J. 2010. A living cell quartz crystal microbalance biosensor for continuous monitoring of cytotoxic responses of macrophages to single-walled carbon engineered nanoparticles. Particle and Fibre Toxicology. Submitted.
  • Vorotnikova E, McIntosh D, Dewilde A, Zhang J, Reing J, Zhang L, Cordero K, Bedelbaeva K, Gourevitch D, Heber-Katz E, Badylak S, Braunhut SJ. 2010. MRL cell matrix-derived products modulate endothelial and progenitor cell migration and proliferation in vitro and stimulate regenerative healing in vivo. Matrix Biology. Accepted
  • Hechavarria, D., Dewilde, A., Braunhut, S., and D. Kaplan. 2010. BioDome Regenerative Sleeve for Biochemical and Biophysical Stimulation of Tissue Regeneration. Journal of Medical Engineering and Physics. Med Eng Phys. 2010 Aug 12. [Epub ahead of print]
  • Vorotnikova E, Rosenthal R, Tries M, Doctrow S, Braunhut SJ. 2010. Novel synthetic SOD mimetics can mitigate capillary endothelial cell apoptosis caused by ionizing radiation. Radiation Research. Jun; 173(6): 748-59.
  • Wang G, Badylak S, Braunhut SJ, Heber-Katz E, Odelberg S, Gudas L. 2010. The effects of DNA methyltransferase inhibitors and histone deacetylase inhibitors on digit regeneration in the mouse. Regenerative Medicine Mar; 5(2)201-20.
  • Agrawal V, Johnson S, Reing J, Zhang L, Tottey S, Wang G, Hirschi K, Braunhut SJ, Gudas L, Badylak S. 2010. An epimorphic regeneration approach to tissue replacement in adult mammals. PNAS. Feb 23; 107(8):3351-5. Dec. 4 [Epub ahead of print].
  • Nagarajan S, Nagarajan R, Braunhut SJ, Bruno F, McIntosh D, Samuelson L, Kumar J. 2008. Biocatalytically oligomerized epicatechin with potent and specific anti-proliferative activity for human breast cancer cells. Molecules. Nov 1;13(11):2704-16.PMID: 18978700
  • Marx KA, Zhou T, McIntosh D, Braunhut SJ. 2009. Electropolymerized tyrosine-based thin films: selective cell binding via peptide recognition to novel electropolymerized biomimetic tyrosine RGDY films. Anal Biochem. Jan 1;384(1):86-95. Epub 2008 Sep 25.PMID: 18926794
  • Reing JE, Zhang L, Myers-Irvin J, Cordero KE, Freytes DO, Heber-Katz E, Bedelbaeva K, McIntosh D, Dewilde A, Braunhut SJ, Badylak SF. 2009. Degradation products of extracellular matrix affect cell migration and proliferation. Tissue Eng Part A. Mar;15(3):605-14.PMID: 18652541
  • Marx KA, Zhou T, Montrone A, McIntosh D, Braunhut SJ. 2007 A comparative study of the cytoskeleton binding drugs nocodazole and taxol with a mammalian cell quartz crystal microbalance biosensor: Different dynamic responses and energy dissipation effects.Anal Biochem. 1;361(1):77-92. Epub 2006.
  • Marx, KA, T. Zhou, A. Montrone, D. McIntosh, and Braunhut, S. J. 2005 Quartz crystal microbalance biosensor study of endothelial cells and their extracellular matrix following cell removal: evidence for transient cellular stress and viscoelastic changes during detachment and the elastic behavior of the pure matrix. Analytical Biochemistry. 343:23-34.
  • Vorotnikova E., Ivkov R., Foreman A., Tries M., Braunhut, S. J. . 2005 The Magnitude and Time-Dependence of the Apoptotic Response of Normal and Malignant Cells Subjected to Varying Treatments of Ionizing and Thermal Radiation. International. J. Radiation Biology.
  • Braunhut, S.J., D. McIntosh, E. Vorotnikova, T. Zhou and K. Marx. 2005 Detection of apoptosis and drug resistance of human breast cancer cells to taxane treatments using quartz crystal microbalance biosensor technology. Assay and Drug Development Technologies, 3:1-12.
  • Vorotnikova, K, Tries, M and Braunhut, S.J. 2004 Radiation induced apoptosis in capillary endothelial cells: Protection by retinoids and tissue inhibitors of matrix metalloproteinases (TIMP). Radiation Research, 161: 174-184.
  • Braunhut, S. J., McIntosh, D., Vorotnikova, E. , Zhou, T. and K. A. Marx. 2004. A new assay to detect and distinguish human cancer cell response and drug resistance to docetaxel and paclitaxel treatments. Experimental Cell Research.
  • Marx, K.A., Zhou, T., MacIntosh D. and Braunhut, S. J. 2004. Extracellular Matrix Studied in situ with the Quartz Crystal Microbalance: Documenting Cellular Stress During Removal and the Elastic Behavior of the Matrix. Journal of Material Research.
  • Marx, K.A., Zhou, T., MacIntosh D. and Braunhut, S. J. 2004. Evidence for Cell-Cell Cooperativity in Initial Adhesion and Spreading: A Quartz Crystal Microbalance Study. Journal of Material Research.
  • Braunhut, S. J., McIntosh, D., Vorotnikova, E. , Zhou, T. and K. A. Marx. 2004. Development of a Smart Bandage: Applying electrical potential to selectively release wound healing growth factors from cell free extracellular matrices. Journal of Material Research.
  • Marx, K.A., Zhou, T., MacIntosh D. and Braunhut, S. J. 2004. Electropolymerization of biomimetic peptide-tyrosineamide polymer films for specific cell attachment. Journal of Material Research.
  • Vorononikova, E., Tries, M, andBraunhut, S. J. 2004. Retinoids and TIMP1 prevent radiation-induced apoptosis of vascular endothelial cells. Rad Res. 161:174-84.
  • Zhou, T., K.A. Marx, M. Warren, H. Schulze and Braunhut, S. J.2003. Hydrophilic Modification of the Quartz Crystal Microbalance Gold Surface Improves Endothelial Cell Adhesion and Spreading, Biotechnology Progress. 19:987-99.
  • Marx, K.A., T. Zhou, A. Montrone and Braunhut, S. J. 2002. A Quartz Crystal Microbalance Cell Biosensor: Detecting Nocodazole Dependent Microtubule Disruption Dynamics in Living Cells, Advanced Biomaterials-Characterization, Tissue Engineering and Complexity, Pittsburgh, PA., 711:125-132.
  • Marx, K.A., Zhou, T., Montrone, A., Schulze, H., and Braunhut, S. J.. 2001, A quartz crystal microbalance cell biosensor: Detection of microtubule alterations in living cells at nM nocodazole concentrations.Biosensors and Bioelectronics. 16:773-782.
  • Warren MC, Bump EA, Medeiros D, Braunhut SJ. 2001. Oxidative stress induced apoptosis of endothelial cells. Free Radic Biol Med. 29(6):537-47.
  • Zhou T, Marx KA, Warren M, Schulze H, Braunhut SJ. 2000. The quartz crystal microbalance as a continuous monitoring tool for the study of endothelial cell surface attachment and growth. Biotechnol Prog. 16(2):268-77.
  • Zhou, T., Braunhut S.J., Medeiros, D., K.A. Marx. 2000. Cellular adhesion and spreading of endothelial cells monitored in real time using the quartz crystal microbalance. MRS- Journal. 550: 177-182.
  • Zhou, T., Braunhut S.J., Medeiros, D., K.A. Marx. 1998. Potential dependent endothelial cell adhesion, growth and cytoskeletal rearrangement. MRS. 489: 211-216.
  • van Kleef, E.M., te Poele, J.A., Oussoren, Y.G., Verheij, M., van de Pavert, I., Braunhut S.J.,Dewit L.G., F.A. Stewart. 1998. Increased expression of glomerular von Willebrand factor after irradiation of the mouse kidney. Radiation Res. 150:528-34.
  • Langley, R.D., Bump, E.A., Quartuccio, S.G., Medeiros, D. and Braunhut, S. J. 1997. Radiation-induced apoptosis in microvascular endothelial cells. Brit. J. Cancer Res. 75:666-672
  • Braunhut, S.J., Medeiros, D., Cerce, B.A., Lai, L.L. and Bump, E.A. 1996. The effects of TEMPOL and ionizing radiation on the endothelial cell wound healing response. British Journal of Cancer Res. 74: 157-161.
  • Braunhut SJ, Medeiros D, Lai L, Bump EA. 1996. Tempol prevents impairment of the endothelial cell wound healing response caused by ionising radiation.Br J Cancer Suppl. 27:S157-60.
  • Kostyk, S., Kourembanas, S., Wheeler, E., Medeiros, D., McQuillan, L., DAmore, P and Braunhut, S. J.1995. Basic fibroblast growth factor increases nitric oxide synthase production in bovine endothelial cells. Amer. J. Physiol. 269:1583-1589.
  • Bump, E.A., Braunhut, S.J.,Palayoor, S.T., Medeiros, D., Lai, L.L., Cerce, B., Langley, R.E. and Coleman, C. N. 1994. Novel concepts in modification of radiation sensitivity. Internat. J Radiation Oncology Biol. Phys., 29: 249 253.
  • Braunhut, S.J. and Moses, M.A. 1994. Retinoids Modulate Endothelial Cell Production of Matrix degrading Proteases and Tissue Inhibitors of Metalloproteinases (TIMP). J. Biol. Chem. 269, 18: 13472 13479.
  • Braunhut, S.J., DAmore, P.A. and Gudas, L. 1992. The location and expression of fibroblast growth factor (FGF) by F9 visceral and parietal embryonic cells after retinoic acid induced differentiation. Differentiation, 50: 141 152.
  • Paige, K., Palornares, M., DAmore, P. and Braunhut, S.J.1991. Retinol induced modification of the extracellular matrix of endothelial cells Jts role in growth control. In, Vitro Cellular Developmental Biology, 27: 151 157.
  • Braunhut, S.J. and Palomares, M. 1991. Modulation of endothelial cell shape and growth by retinbids. Microvasc Res. 47 62.
  • Braunhut, S.J., Rufo, G.A., Ernisse, B., Zheng, W. and Bellve', A. 1990. The seminiferous growth factor induces proliferation of TM4 cells in serum free media. Biol. Reprod. 42:639 648.
  • Braunhut, S.J., Gudas, L.J., Kurokawa, T., Sasse, J. and D'Amore, P.A. 1989. Expression of fibroblast growth factor by F9 teratocarcinoma cells as a function of differentiation. J. Cell Biol., 108: 2467 2476.
  • Persson, H., Gray, H.D., Godeau, F., Braunhut, S. J. and Bellve’, A.R. 1986. Multiple growth-associated nuclear proteins immunoprecipitated by antisera against human c-myc peptide antigens. Molecular Cell Biol., 6: 942-949.
  • Bellve, A.R., Stewart, T.A., Braunhut, S.J., Ernisse, B.J., Rufo, G.A. 1986. The seminiferous growth factor (SGF): A candidate for regulating cell proliferation during development of the mammalian testes. Proc. Australian Soc. Study Reprod., 8: 10-22.
  • Bellve, A.R., Stewart, T.A., Braunhut, S.J., Ernisse, B.J., Rufo, G.A. 1984. The regulation of cell proliferaton during development of the mammalian testes. Proc. Serono Sym. on Development and Function of the Reproductive Organs. Raven Press, Serono, Israel, 1-24.
  • Braunhut, S.J., Blanc, W., Ramanarayanan, M., Marboe, C. and Mesa-Tajada, R. 1984. Immunocytochemical localization of lyzosome and alpha-1 antichymotrypsin in the term human placenta: An attempt to characterize the Hofbauer cell. J. Histochem. Cytochem. 32: 1204-1210.
  • Friedman, A.H., Orallana, J., Freeman, W.R., Luntz, M.H., Starr, M.B., Tapper, M.L., Spigland, J. Rotterdam, H., Mesa-Tajada, R.R., Braunhut, S.J., Mildvan, D. & Mather, U. 1983. Cytomegalovirus retinitis: A manifestation of the acquired immune deficiency syndrome (AIDS). Brit J. Ophthal. 67: 372-380.
  • Lefkowitch, J.H., Muschel, R., Price, J.B., Marboe, C., Braunhut, SJ., . Identification of copper-associated protein and alpha-1-anti-trypsin in fibrolamellar liver cell carcinoma. Cancer 51: 97-100.
  • D'Amore, P. and Braunhut, S.J. Stimulatory and inhibitory factors in vascular growth control. In Endothelial Cells, Ryan U, ed. CRC Press, Inc., Boca Raton, FL 13 36. 1988.
  • Persson, H., Gray, H.D., Godeau, F., Braunhut, S. J. and Bellve', A.R. Multiple growthassociated nuclear proteins immunoprecipitated by antisera against human c myc peptide antigens. Molecular Cell Biol., 6: 942 949. 1986.
  • Braunhut, S.J., Blanc, W., Ramanarayanan, M., Marboe, C. and Mesa Tajada, R. Immunocytochemical localization of lyzosome and alpha 1 antichymotrypsin in the term human placenta: An attempt to characterize the Hofbauer cell. J. 11istochem. Cytochem. 32: 12041210.1984.
  • Friedman, A.H., Orallana, J., Freeman, W.R., Luntz, M.H., Starr, M.B., Tapper, M.L., Spigland, J. Rotterdam, H., Mesa Tajada, R.R., Braunhut, S.J., Mildvan, D. & Mather, U. Cytomegalovirus retinitis: A manifestation of the acquired immune deficiency syndrome (AIDS). Brit J. Ophthal. 67: 372 380. 1983.
  • Lefkowitch, J.H., Muschel, R., Price, J.B., Marboe, C., Braunhut, SJ., Identification of copperassociated protein and alpha 1 anti trypsin in fibrolamellar liver cell carcinoma. Cancer 51: 97 100. 1983.