Assistant Professor Kristina Deligiannidis
Assistant Professor received an M.D. and completed a psychiatric residence and a chief residency in psychopharmacology research at UMass Medical School. She currently serves as the Director of the Depression Specialty Clinic at UMass Memorial Health Care. She conducts translational research in the causes of depression in women in pregnancy and the postpartum period. Her research interests include psychoneuroendocrinology (hypothalamic-pituitary-adrenal and gonadal axes, gonadal hormones and neuroactive steroids); the neuroimaging and neuroendocrine biomarkers of depression in women during pregnancy and the postpartum period; gender differences in depression; and the use of neuroimaging (e.g., MRS, fcMRI, PET) in depression research. She is active in curriculum development and teaching in the areas of psychopharmacology, evidence-based medicine and women's mental health.
Professor Jean Frazier, Professor
Professor Frazier earned an M.D. from Dartmouth Medical School, completed residencies at the Tufts-New England Medical Center, and did a research fellowship in child psychiatry at the National Institute of Mental Health in Maryland. She serves as a Co-Director of the Child and Adolescent Neurodevelopment Initiative (CANDI) and holds the Robert M. and Shirley S. Siff Chair in Autism at UMass Medical School. She directs a broad research program focused on the understanding, diagnosis and treatment of individuals with neurodevelopment disorders such as early onset bipolar disorder (BPD), schizophrenia and autism. She studies all three diagnostic groups since there is overlap in the clinical symptoms, genetics, and neuroimaging findings of these disorders. One of her aims is to find biomarkers specific to each diagnosis. Her current grant work involves pharmaceutical and pharmacokinetic studies, hormone studies, and neuroimaging.
Associate Professor Carl Fulwiler
Associate Professor Fulwiler received an M.D. from the Washington University School of Medicine in St. Louis and a PhD in Neurobiology from Harvard University. He did research and clinical fellowships in Psychiatry at Harvard and taught at Tufts University before joining UMass Medical School. He currently serves as the Director of the Center for Mental Health Services Research at UMMS and the Director of Clinical Neuroscience at Lemuel Shattuck Hospital. His research focuses on forensic populations, co-occurring mental health and substance addictions, veterans' trauma treatment, and anger management. Specific studies include the pharmacotherapeutic effects of antipsychotic drugs, genetic investigations of certain proteins in Alzheimer's disease brains, and mapping neural markers of aggression.
Professor Jean King
Professor King earned her Ph.D. in neurophysiology from New York University and completed a postdoctoral fellowship at Emory University in Atlanta. She serves as the Vice-Chair of Research for the Department of Psychiatry and the Director of the Center for Comparative NeuroImaging (CCNI) at UMass Medical School. She also holds a Research Professor position in the Department of Biomedical Engineering at Worcester Polytechnic Institute. Her research includes studies on the consequences of childhood stress; the use of brain imaging for diagnosis and treatment of stress-induced disorders; and magnetic imaging focusing on drug responses and addictions, including nicotine, ethanol, cocaine, epilepsy-related drugs, anti-addiction drugs, antipsychotics and anesthetics. She has received grants from both public and private agencies, among them the National Institutes of Health, the National Science Foundation, the Centers for Disease Control, Pfizer Inc, and Rexahn Pharmaceuticals. She is currently working on two NIH grants examining the effects of nicotine administration on brain activity.
Associate Professor Haley Melikian
Associate Professor Melikian holds a Ph.D. in neuroscience from Emory University and completed postdoctoral fellowships at the Howard Hughes Medical Institute at Emory University and at Harvard Medical School. She holds a joint appointment at UMass Medical School between the Department of Psychiatry and the Department of Biochemistry and Molecular Pharmacology. Her research focuses on cellular regulation of cocaine- and antidepressant-sensitive neurotransmitter transporters: the signaling, neurotransmission, and blocking of transporters specific for monoamines (such as dopamine and norepinephrine). She has published articles in Clinical Neuropharmacology, Molecular Pharmacology, Pharmacology & Therapeutics, and the Journal of Neurochemistry, among others. She is currently working on an NIH grant investigating the cellular and molecular mechanisms governing basal, protein kinase C-regulated and amphetamine-regulated dopamine transporter (DAT) trafficking.
Associate Professor Constance Moore
Associate Professor Moore took her Ph.D. in Physics from University College Dublin and completed a fellowship in spectroscopy/neuroscience at Harvard Medical School. Her PhD thesis was on the application of proton Magnetic Resonance Spectroscopy (MRS) in schizophrenia and was one of the first applications of the technique in mental illness. She currently serves as the Associate Director of Translational Imaging at the Center for Comparative NeuroImaging (CCNI) at UMass Medical School. Her research focuses on using imaging techniques, particularly MRI, to measure brain chemistry. She primarily studies mood disorders, with an emphasis on mood disorders in children and adolescents, including how brain chemistry changes with brain development, the effects of medication (especially lithium) on cerebral metabolism, and how cognition and mood are affected by different metabolite concentrations.
Professor Anthony Rothschild
Professor Rothschild received his M.D. from the University of Pennsylvania School of Medicine and completed residencies in psychiatry and psychopharmacology at McLean Hospital in Belmont, Massachusetts. He also completed a clinical fellowship in psychiatry at Harvard Medical School and a research fellowship in neurochemistry at McLean Hospital. He taught at Harvard Medical School before joining UMass Medical School. He currently holds the Irving S. and Betty Brudnick Endowed Chair of Psychiatry at UMMS. He is the Director of the Center for Psychopharmacologic Research and Treatment as well as the Director of the Psychopharmacology Fellowship Program at UMMS. His primary research interests are the neurological bases and pharmacological treatment of depressive and anxiety disorders. A particular focus of his research has been on increasing understanding of pathophysiology and treatment of psychotic depression.
Assistant Professor Nanyin Zhang
Assistant Professor Zhang received a PhD in Biomedical Engineering from the University of Minnesota, and completed a postdoctoral and a research fellowship in the Center of Magnetic Resonance Research (CMRR) at the University of Minnesota. He taught at the University of Minnesota before joining UMass Medical School. His research interests focus on applications of functional magnetic resonance imaging (fMRI) to understand neural responses and brain circuitry at normal conditions and in various mental disorders; applications of fMRI include imaging nicotine addiction in rodents and humans. He has done studies on the biomarkers of nicotine addiction and the effects of nicotine administration on neural response as well as the impact of anesthesia on resting-state functional connectivity. He serves as a reviewer for almost 20 academic journals, including Psychopharmacology and the Journal of Neuroscience. He is currently managing a grant, funded by Takeda Pharmaceuticals North America, that evaluates the effects of a proprietary drug on resting-state functional connectivity in rat brains.