36.709 Pharmacogenomic Principles and Applications

Pharmacogenomic Principles and Applications

Course Details
Min Credits 3
Max Credits 3
Course ID 37847
Status Active

Pharmacogenomics utilizes knowledge related to the variability in the human genome to understand and predict the differences in drug response and toxicity of pharmaceutical agents. This includes not only the determination of pharmacologically relevant genes that alter individual pharmacokinetic and pharmacodynamic response but also those polymorphism's and other mutations that predispose a person to development of various diseases. Personalizing therapies based on genotypic information should increase efficacy and decrease toxicity of agents. Current applications covered include anti-cancer and anti-viral therapies and anticoagulation.

Pre/Co-Requisites: Pre-req: 36.707 Drug Metabolism